vetmed

CROHN'S DISEASE AND MAP DIGEST

Updated 11 November 2013
Database maintained by the OIE Reference Laboratory for Paratruberculosis (VRI Brno).
Search profile: (mycobact* OR muramyl* OR peptidoglycan* OR glycan*) AND (autoimmun* OR Crohn*).
Imported from the Web of Science® database (Thomson Reuters).

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Year:   Author:  

Altered Sympathetic-to-Immune Cell Signaling via beta(2)-Adrenergic Receptors in Adjuvant Arthritis NEW
Lorton D, Bellinger DL, Schaller JA, Shewmaker E, Osredkar T, Lubahn C
Clinical & Developmental Immunology none, 2013, Article Number: 764395 DOI: 10.1155/2013/764395 Published: 2013


Protein Tyrosine Phosphatase Non-Receptor Type 22 Modulates NOD2-Induced Cytokine Release and Autophagy NEW
Spalinger MR, Lang S, Vavricka SR, Fried M, Rogler G, Scharl M
Plos One 8, 2013, Article Number: e72384 DOI: 10.1371/journal.pone.0072384 Published: AUG 26 2013


Detection of muramyl dipeptide-sensing pathway defects in monocytes of patients with Crohn's disease using phospho-specific whole blood flow cytometry NEW
Kuuliala K, Lappalainen M, Turunen U, Puolakkainen P, Kemppainen E, Siitonen S, Repo H, Mustonen H
Scandinavian Journal of Clinical & Laboratory Investigation 73, 2013, 494-502


Glycolipid antigens and autoantibodies in autoimmune neuropathies NEW
Willison HJ, Goodyear CS
Trends in Immunology 34, 2013, 453-459


NOD1 and NOD2 receptors: integral members of the innate and adaptive immunity system NEW
Antosz H, Osiak M
Acta Biochimica Polonica 60, 2013, 351-360


Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway NEW
Rickard DJ, Sehon CA, Kasparcova V, Kallal LA, Zeng X, Montoute MN, Chordia T, Poore DD, Li H, Wu ZN, Eidam PM, Haile PA, Yu J, Emery JG, Marquis RW, Gough PJ, Bertin J
Plos One 8, 2013, Article Number: e69619 DOI: 10.1371/journal.pone.0069619 Published: AUG 1 2013


NOD2 Mutations Affect Muramyl Dipeptide Stimulation of Human B Lymphocytes and Interact with Other IBD-Associated Genes NEW
Lin ZW, Hegarty JP, John G, Berg A, Wang Z, Sehgal R, Pastor DM, Wang YH, Harris LR, Poritz LS, Schreiber S, Koltun WA
Digestive Diseases and Sciences 58, 2013, 2599-2607


Identification of a synthetic muramyl peptide derivative with enhanced Nod2 stimulatory capacity NEW
Rubino SJ, Magalhaes JG, Philpott D, Bahr GM, Blanot D, Girardin SE
Innate Immunity 19, 2013, 493-503


Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation NEW
Corridoni D, Kodani T, Rodriguez-Palacios A, Pizarro TT, Xin W, Nickerson KP, McDonald C, Ley KF, Abbott DW, Cominelli F
Proceedings of the National Academy of Sciences of the United States of America 110, 2013, 16999-17004


Genetic Association of Peptidoglycan Recognition Protein Variants with Inflammatory Bowel Disease
Zulfiqar F, Hozo I, Rangarajan S, Mariuzza RA, Dziarski R, Gupta D
Plos One 8, 2013, Article Number: e67393 DOI: 10.1371/journal.pone.0067393 Published: JUN 19 2013


Analysis of Transcriptional Profiles to Discover Biomarker Candidates in Mycobacterium avium subsp paratuberculosis-Infected Macrophages, RAW 264.7
Cha SB, Yoo A, Park HT, Sung KY, Shin MK, Yoo HS
Journal of Microbiology and Biotechnology 23, 2013, 1167-1175


IL-23 Receptor Expression on gamma delta T Cells Correlates with Their Enhancing or Suppressive Effects on Autoreactive T Cells in Experimental Autoimmune Uveitis
Liang DC, Zuo AJ, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun DM
Journal of Immunology 191, 2013, 1118-1125


Muramyl dipeptide responsive pathways in Crohn's disease: from NOD2 and beyond
Salem M, Seidelin JB, Rogler G, Nielsen OH
Cellular and Molecular Life Sciences 70, 2013, 3391-3404


LRRK2 and RIPK2 Variants in the NOD 2-Mediated Signaling Pathway Are Associated with Susceptibility to Mycobacterium leprae in Indian Populations
Marcinek P, Jha AN, Shinde V, Sundaramoorthy A, Rajkumar R, Suryadevara NC, Neela SK, van Tong H, Balachander V, Valluri VL, Thangaraj K, Velavan TP
Plos One 8 , 2013, Article Number: e73103 DOI: 10.1371/journal.pone.0073103 Published: AUG 28 2013


Comparative genomics of Campylobacter concisus isolates reveals genetic diversity and provides insights into disease association
Deshpande NP, Kaakoush NO, Wilkins MR, Mitchell HM
Bmc Genomics 14 , 2013, Article Number: 585 DOI: 10.1186/1471-2164-14-585 Published: AUG 28 2013


Crohn's disease-specific pancreatic autoantibodies are specifically present in ruminants with paratuberculosis: Implications for the pathogenesis of the human disease
Liaskos C, Spyrou V, Roggenbuck D, Athanasiou LV, Orfanidou T, Mavropoulos A, Reinhold D, Rigopoulou EI, Amiridis GS, Billinis C, Bogdanos DP
Autoimmunity 46, 2013, 388-394


Extended haplotype association study in Crohn's disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-kappa B pathway gene, HEATR3
Zhang W, Hui KY, Gusev A, Warner N, Ng SME, Ferguson J, Choi M, Burberry A, Abraham C, Mayer L, Desnick RJ, Cardinale CJ, Hakonarson H, Waterman M, Chowers Y, Karban A, Brant SR, Silverberg MS, Gregersen PK, Katz S, Lifton RP, Zhao H, Nunez G, Pe'er I, Peter I, Cho JH
Genes and Immunity 14, 2013, 310-316


Granulomas of Intestinal Tuberculosis and Crohn's Disease Can Be Differentiated by CD73 Cell Surface Marker Expression: A Pilot Study
Banerjee R, Balaji M, Sasikala M, Anuradha S, Rao GV, Reddy DN
Digestive Diseases and Sciences 58, 2013, 2301-2307


Exacerbation of latent lupus: is the culprit acid-fast bacilli or antitubercular therapy?
Singh H, Ray S, Kaur M, Gupta V, Kumar H, Talapatra P, Mathur R, Arya S, Ghangas N
Clinical Rheumatology 32, 2013, 1233-1236


Microarray Analysis Reveals the Molecular Basis of Antiarthritic Activity of Huo-Luo-Xiao-Ling Dan
Yu H, Lee DYW, Nanjundaiah SM, Venkatesha SH, Berman BM, Moudgil KD
Evidence-Based Complementary and Alternative Medicine none, 2013, Article Number: 524746 DOI: 10.1155/2013/524746 Published: 2013


A central role for inducible heat-shock protein 70 in autoimmune vitiligo
Mosenson JA, Eby JM, Hernandez C, Le Poole IC
Experimental Dermatology 22, 2013, 566-569


Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells
Trinath J, Hegde P, Sharma M, Maddur MS, Rabin M, Vallat JM, Magy L, Balaji KN, Kaveri SV, Bayry J
Blood 122, 2013, 1419-1427


Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
Yang S, Wang BW, Humphries F, Jackson R, Healy ME, Bergin R, Aviello G, Hall B, McNamara D, Darby T, Quinlan A, Shanahan F, Melgar S, Fallon PG, Moynagh PN
Nature Immunology 14, 2013, 927-+


NOD2-Mediated Innate Immune Signaling Regulates the Eicosanoids in Atherosclerosis
Liu HQ, Zhang XY, Edfeldt K, Nijhuis MO, Idborg H, Back M, Roy J, Hedin U, Jakobsson PJ, Laman JD, de Kleijn DP, Pasterkamp G, Hansson GK, Yan ZQ
Arteriosclerosis Thrombosis and Vascular Biology 33, 2013, 2193-2201


N-glycomic biomarkers of biological aging and longevity: A link with inflammaging
Dall'Olio F, Vanhooren V, Chen CC, Slagboom PE, Wuhrer M, Franceschi C
Ageing Research Reviews 12, 2013, 685-698


Anti-IFN-gamma autoantibodies in adults with disseminated nontuberculous mycobacterial infections are associated with HLA-DRB1*16:02 and HLA-DQB1*05:02 and the reactivation of latent varicella-zoster virus infection
Chi CY, Chu CC, Liu JP, Lin CH, Ho MW, Lo WJ, Lin PC, Chen HJ, Chou CH, Feng JY, Fung CP, Sher YP, Li CY, Wang JH, Ku CL
Blood 121, 2013, 1357-1366


Leprosy, a pillar of human genetics of infectious diseases
Gaschignard J, Scurr E, Alcais A
Pathologie Biologie 61, 2013, 120-128


General mechanism for modulating immunoglobulin effector function
Sondermann P, Pincetic A, Maamary J, Lammens K, Ravetch JV
Proceedings of the National Academy of Sciences of the United States of America 110, 2013, 9868-9872


Glucosamine Induces Activated T Cell Apoptosis Through Reduced T Cell Receptor
Chen NH, Cheong KA, Kim CH, Noh M, Lee AY
Scandinavian Journal of Immunology 78, 2013, 17-27


Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis
Macauley MS, Pfrengle F, Rademacher C, Nycholat CM, Gale AJ, von Drygalski A, Paulson JC
Journal of Clinical Investigation 123, 2013, 3074-3083


Recognition of bacterial infection by innate immune sensors
Kumar S, Ingle H, Prasad DVR, Kumar H
Critical Reviews in Microbiology 39, 2013, 229-246


The regulatory power of glycans and their binding partners in immunity
Johnson JL, Jones MB, Ryan SO, Cobb BA
Trends in Immunology 34, 2013, 290-298


Differential Involvement of Th1 and Th17 in Pathogenic Autoimmune Processes Triggered by Different TLR Ligands
Shi GP, Vistica BP, Nugent LF, Tan CY, Wawrousek EF, Klinman DM, Gery I
Journal of Immunology 191, 2013, 415-423


NOD-like receptors mediated activation of eosinophils interacting with bronchial epithelial cells: a link between innate immunity and allergic asthma
Wong CK, Hu SQ, Leung KML, Dong J, He L, Chu YJ, Chu IMT, Qiu HN, Liu KYP , Lam CWK
Cellular & Molecular Immunology 10, 2013, 317-329


Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn's disease patients
MoliCotti P, Scanu AM, Lumbau A, Cannas S, Bua A, Luglie P, Zanetti S
Gut Pathogens 5, 2013, Article Number: 18 DOI: 10.1186/1757-4749-5-18 Published: JUL 10 2013


Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome
Uzel G, Sampaio EP, Lawrence MG, Hsu AP, Hackett M, Dorsey MJ, Noel RJ, Verbsky JW, Freeman AF, Janssen E, Bonilla FA, Pechacek J, Chandrasekaran P, Browne SK, Agharahimi A, Gharib AM, Mannurita SC, Yim JJ, Gambineri E, Torgerson T, Tran DQ, Milner JD, Holland SM
Journal of Allergy and Clinical Immunology 131, 2013, 1611-DOI: 10.1016/j.jaci.2012.11.054 Published: JUN 2013


Exploring the role of Mycobacterium avium subspecies paratuberculosis in the pathogenesis of type 1 diabetes mellitus: a pilot study
Naser SA, Thanigachalam S, Dow CT, Collins MT
Gut Pathogens 5, 2013, Article Number: 14 DOI: 10.1186/1757-4749-5-14 Published: JUN 13 2013


Tumour necrosis factor antagonist and tuberculosis in patients with rheumatoid arthritis: An Asian perspective
To KW, Reino JJG, Yoo DH, Tam LS
Respirology 18, 2013, 765-773


Shaping Intestinal Bacterial Community by TLR and NLR Signaling
Kobayashi KS
Guarino A_Quigley EMM_Walker WA (eds): Probiotic Bacteria and Their Effect on Human Health and Well-Being. World Rev Nutr Diet. Basel_Karger_2013, vol 107, pp 32-42 (DOI:10.1159/000346493)


In silico investigation of novel biological pathways: The role of CD200 in regulation of T cell priming in experimental autoimmune encephalomyelitis
Greaves RB, Read M, Timmis J, Andrews PS, Butler JA, Gerckens BO, Kumar V
Biosystems 112, 2013, 107-121


Cord Factor and Peptidoglycan Recapitulate the Th17-Promoting Adjuvant Activity of Mycobacteria through Mincle/CARD9 Signaling and the Inflammasome
Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, Oland S, Hieny S, Caspar P, Yamasaki S, Lin X, Ting JPY, Trinchieri G, Besra GS, Cerundolo V, Sher A
Journal of Immunology 190, 2013, 5722-5730


Mycobacterial and mouse HSP70 have immuno-modulatory effects on dendritic cells
Spiering R, van der Zee R, Wagenaar J, Van Eden W , Broere F
Cell Stress & Chaperones 18, 2013, 439-446


Effector T-cell responses in non-lymphoid tissues: insights from in vivo imaging
Mueller SN
Immunology and Cell Biology 91, 2013, 290-296


Pathogenesis of immunoglobulin A nephropathy
Novak J, Renfrow MB, Gharavi AG, Julian BA
Current Opinion in Nephrology and Hypertension 22, 2013, 287-294


Autophagy as an innate defense against mycobacteria
Jo EK
Pathogens and Disease 67, 2013, 108-118


Cytokine gene expression in intestinal tuberculosis and Crohn's disease
Pugazhendhi S, Jayakanthan K, Pulimood AB, Ramakrishna BS
International Journal of Tuberculosis and Lung Disease 17, 2013, 662-668


Therapeutic potential of Galectin-9 in human disease
Wiersma VR, de Bruyn M, Helfrich W, Bremer E
Medicinal Research Reviews 33, 2013, E102-E126


Yield and cost effectiveness of mycobacterial infection detection using a simple IGRA-based protocol in UK subjects with inflammatory bowel disease suitable for anti-TNF alpha therapy
Greveson K, Goodhand J, Capocci S, Woodward S, Murray C, Cropley I, Hamilton M, Lipman M
Journal of Crohns & Colitis 7, 2013, 412-418


A Discrete Ubiquitin-Mediated Network Regulates the Strength of NOD2 Signaling
Tigno-Aranjuez JT, Bai XD, Abbott DW
Molecular and Cellular Biology 33, 2013, 146-158


Evidence supporting a role for dormant bacteria in the pathogenesis of spondylarthritis
Berthelot JM, de la Cochetiere MF, Potel G, Le Goff B, Maugars Y
Joint Bone Spine 80, 2013, 135-140


Infliximab for Crohn's Disease: The First 500 Patients Followed Up Through 2009
Seminerio JL, Loftus EV, Colombel JF, Thapa P, Sandborn WJ
Digestive Diseases and Sciences 58, 2013, 797-806


Self-eating and self-defense: autophagy controls innate immunity and adaptive immunity
Liu GW, Bi YJ, Wang RN, Wang XH
Journal of Leukocyte Biology 93, 2013, 511-519


The intermediate filament protein, vimentin, is a regulator of NOD2 activity
Stevens C, Henderson P, Nimmo ER, Soares DC, Dogan B, Simpson KW, Barrett JC, Wilson DC, Satsangi J
Gut 62, 2013, 695-707


The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn's disease
Vasseur F, Sendid B, Broly F, Gower-Rousseau C, Sarazin A, Standaert-Vitse A, Colombel JF, Poulain D, Jouault T
Bmc Medical Genetics 14, 2013, Article Number: 35 DOI: 10.1186/1471-2350-14-35 Published: MAR 18 2013


Glycan Sequence-Dependent Nod2 Activation Investigated by Using a Chemically Synthesized Bacterial Peptidoglycan Fragment Library
Wang N, Huang C , Hasegawa M, Inohara N, Fujimoto Y, Fukase K
Chembiochem 14, 2013, 482-488


p62/SQSTM1 Enhances NOD2-Mediated Signaling and Cytokine Production through Stabilizing NOD2 Oligomerization
Park S, Ha SD, Coleman M, Meshkibaf S, Kim SO
Plos One 8, 2013, Article Number: e57138 DOI: 10.1371/journal.pone.0057138 Published: FEB 20 2013


Nucleotide-Binding Oligomerization Domain 2 Signaling Promotes Hyperresponsive Macrophages and Colitis in IL-10-Deficient Mice
Jamontt J, Petit S, Clark N, Parkinson SJ, Smith P
Journal of Immunology 190, 2013, 2948-2958


Sialoadhesin Ligand Expression Identifies a Subset of CD4(+) Foxp3(-) T Cells with a Distinct Activation and Glycosylation Profile
Kidder D, Richards HE, Ziltener HJ, Garden OA, Crocker PR
Journal of Immunology 190, 2013, 2593-2602


Autophagy and inflammatory diseases
Jones SA, Mills KHG, Harris J
Immunology and Cell Biology 91, 2013, 250-258


NLRP1 and NLRP3 inflammasomes are essential for distinct outcomes of decreased cytokines but enhanced bacterial killing upon chronic Nod2 stimulation
Hedl M, Abraham C
American Journal of Physiology-Gastrointestinal and Liver Physiology 304, 2013, G583-G596


Ubiquitin Regulates Caspase Recruitment Domain-mediated Signaling by Nucleotide-binding Oligomerization Domain-containing Proteins NOD1 and NOD2
Heul AMV, Fowler CA, Ramaswamy S, Piper RC
Journal of Biological Chemistry 288, 2013, 6890-6902


Anti-Tumor Necrosis Factor alpha Prevents Bowel Fibrosis Assessed by Messenger RNA, Histology, and Magnetization Transfer MRI in Rats With Crohn's Disease
Adler J, Rahal K, Swanson SD, Schmiedlin-Ren P, Rittershaus AC, Reingold LJ , Brudi JS, Shealy D, Cai A, McKenna BJ, Zimmermann EM
Inflammatory Bowel Diseases 19, 2013, 683-690


Hypomorphic MGAT5 polymorphisms promote multiple sclerosis cooperatively with MGAT1 and interleukin-2 and 7 receptor variants
Li CF, Zhou RW, Mkhikian H, Newton BL, Yu ZX, Demetriou M
Journal of Neuroimmunology 256, 2013, 71-76


I kappa B kinase alpha (IKK alpha) activity is required for functional maturation of dendritic cells and acquired immunity to infection
Mancino A, Habbeddine M, Johnson E, Luron L, Bebien M, Memet S, Fong C, Bajenoff M, Wu XF, Karin M, Caamano J, Chi HB, Seed M, Lawrence T
Embo Journal 32, 2013, 816-828


The prevalence of disseminated Mycobacterium avium subsp paratuberculosis infection in tissues of healthy ewes from a New Zealand farm with Johne's disease present
Smith SL, West DM, Wilson PR, de Lisle GW, Collett MG, Heuer C, Chambers JP
New Zealand Veterinary Journal 61, 2013, 41-44


Assessment of microbiota and peptidoglycan in perianal fistulas
van Onkelen RS, Mitalas LE, Gosselink MP, van Belkum A, Laman JD, Schouten WR
Diagnostic Microbiology and Infectious Disease 75, 2013, 50-54


Genomics and epigenomics of the human glycome
Zoldos V, Novokmet M, Beceheli I, Lauc G
Glycoconjugate Journal 30, 2013, 41-50


Glycomics using mass spectrometry
Wuhrer M
Glycoconjugate Journal 30, 2013, 11-22


A Genome-Wide siRNA Screen Reveals Positive and Negative Regulators of the NOD2 and NF-kappa B Signaling Pathways
Warner N, Burberry A, Franchi L, Kim YG, McDonald C, Sartor MA, Nunez G
Science Signaling 6, 2013, Article Number: rs3 DOI: 10.1126/scisignal.2003305 Published: JAN 15 2013-..


Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells
Garcia-Vallejo JJ, Ambrosini M, Overbeek A, van Riel WE, Bloem K, Unger WWJ, Chiodo F, Bolscher JG, Nazmi K, Kalay H, van Kooyk Y
Molecular Immunology 53, 2013, 387-397


Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers
Lauc G, Huffman JE, Pucic M, Zgaga L, Adamczyk B, Muzinic A, Novokmet M, Polasek O, Gornik O, Kristic J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, Patrick AL , McKeigue P, Kolcic I, Lukic IK, Swann O, van Leeuwen FN, Ruhaak LR, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJM, Deelder AM, Zeng Q, Wang W, Hastie ND, Gyllensten U, Wilson JF, Wuhrer M, Wright AF, Rudd PM, Hayward C, Aulchenko Y, Campbell H, Rudan I
Plos Genetics 9, 2013, Article Number: e1003225 DOI: 10.1371/journal.pgen.1003225 Published: JAN 2013-..


Recommendations for identifying Crohn's disease patients with poor prognosis
Miheller P, Kiss LS, Juhasz M, Mandel M, Lakatos PL
Expert Review of Clinical Immunology 9, 2013, 65-76


Crohn's as an immune deficiency: from apparent paradox to evolving paradigm
Vinh DC, Behr MA
Expert Review of Clinical Immunology 9, 2013, 17-30


Effects of the probiotic Lactobacillus animalis in murine Mycobacterium avium subspecies paratuberculosis infection
Karunasena E, Kurkure PC, Lackey RD, McMahon KW, Kiernan EP, Graham S, Alabady MS, Campos DL, Tatum OL, Brashears MM
Bmc Microbiology 13, 2013, Article Number: 8 DOI: 10.1186/1471-2180-13-8 Published: JAN 16 2013-..


Anti-Inflammatory and Antiapoptotic Responses to Infection: A Common Denominator of Human and Bovine Macrophages Infected with Mycobacterium avium Subsp paratuberculosis
Abendano N, Juste RA, onso-Hearn M
Biomed Research International 2013, Article Number: 908348 DOI: 10.1155/2013/908348-..


Quantitative real-time PCR and culture examination of Mycobacterium avium subsp paratuberculosis at farm level
Hanifian S, Khani S, Barzegari A, Shayegh J
Veterinary Microbiology 162, 2013, 160-165


Stories of love and hate: innate immunity and host-microbe crosstalk in the intestine
Rosenstiel P
Current Opinion in Gastroenterology 29, 2013, 125-132


Rapid and Sensitive Method To Identify Mycobacterium avium subsp paratuberculosis in Cow's Milk by DNA Methylase Genotyping
Mundo SL, Gilardoni LR, Hoffman FJ, Lopez OJ
Applied and Environmental Microbiology 79, 2013, 1612-1618


Modulation of Endosomal Toll-Like Receptor-Mediated Immune Responses by Synthetic Oligonucleotides
Kandimalla ER, Agrawal S
Nucleic Acid Drugs 249, 2012, 61-93


Free-ranging Rocky Mountain bighorn sheep and an outbreak of inflammatory bowel disease along the Clark Fork River in Plains, Montana
Pierce ES
Virulence 3, 2012, 546-550


Alteration of GI symptoms in a cow with Johne disease by the dietary organosulfur, 2-mercaptoethanol
Click RE
Virulence 3 , 2012, 543-545


Basic Science for the Clinician 59 Polymorphonuclear Cells: Mechanisms in Human Defense and in the Pathogenesis of Autoimmune Disease
Sigal LH
Jcr-Journal of Clinical Rheumatology 18, 2012, 443-449


Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases
Correa RG, Milutinovic S, Reed JC
Bioscience Reports 32, 2012, 597-608


Subversion of Autophagy in Adherent Invasive Escherichia coli-Infected Neutrophils Induces Inflammation and Cell Death
Chargui A, Cesaro A, Mimouna S, Fareh M, Brest P, Naquet P, rfeuille-Michaud A, Hebuterne X, Mograbi B, Vouret-Craviari V, Hofman P
Plos One 7, 2012, Article Number: e51727 DOI: 10.1371/journal.pone.0051727 Published: DEC 14 2012-..


Inflammatory Bowel Disease: Dysfunction of Autophagy?
Scharl M, Rogler G
Digestive Diseases 30, 2012, 12-19


Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y , Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Buning C, Cohain A, Cichon S, D'Amato M, de Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu XL, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW , Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao HY, Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH
Nature 491, 2012, 119-124


RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition
Lipinski S, Grabe N, Jacobs G, Billmann-Born S, Till A, Hasler R, Aden K, Paulsen M, Arlt A, Kraemer L, Hagemann N, Erdmann KS, Schreiber S, Rosenstiel P
Proceedings of the National Academy of Sciences of the United States of America 109, 2012, 21426-21431


Mycobacteria in water, soil, plants and air: a review
Hruska K, Kaevska M
Veterinarni Medicina 57, 2012, 623-679


Identification of IL18RAP/IL18R1 and IL12B as Leprosy Risk Genes Demonstrates Shared Pathogenesis between Inflammation and Infectious Diseases
Liu H, Irwanto A, Tian HQ, Fu X, Yu YX, Yu GQ, Low H, Chu TS, Li Y, Shi BQ, Chen MF, Sun YH, Yuan CY, Lu N, You JB, Bao FF, Li JH, Liu J, Liu HX, Liu DC, Yu XL, Zhang L, Yang Q, Wang N, Niu GY, Ma SS, Zhou Y, Wang C, Chen SM, Zhang XJ, Liu JJ, Zhang FR
American Journal of Human Genetics 91, 2012, 935-941


The nucleotide-binding oligomerization domain-containing-2 ligand muramyl dipeptide enhances phagocytosis and intracellular killing of Escherichia coli K1 by Toll-like receptor agonists in microglial cells
Ribes S, Adam N , Schutze S, Regen T, Redlich S, Janova H, Borisch A, Hanisch UK, Nau R
Journal of Neuroimmunology 252, 2012, 16-23


Mycobacterium paratuberculosis CobT Activates Dendritic Cells via Engagement of Toll-like Receptor 4 Resulting in Th1 Cell Expansion
Byun EH, Kim WS , Kim JS, Won CJ, Choi HG, Kim HJ, Cho SN, Lee K, Zhang T, Hur GM, Shin SJ
Journal of Biological Chemistry 287, 2012, 38609-38624


Molecular mimicry between HSP 65 of Mycobacterium leprae and cytokeratin 10 of the host keratin: Role in pathogenesis of leprosy
Singh I, Yadav AR, Mohanty KK, Katoch K, Bisht D, Sharma P, Sharma B, Gupta UD, Sengupta U
Cellular Immunology 278, 2012, 63-75


Nod2-Induced Autocrine Interleukin-1 Alters Signaling by ERK and p38 to Differentially Regulate Secretion of Inflammatory Cytokines
Hedl M, Abraham C
Gastroenterology 143, 2012, 1530-1543


Tracheobronchial nodules and pulmonary infiltrates in a patient with Crohn's disease
Lu DG, Ji XQ, Zhao Q, Zhang CQ, Li ZF
World Journal of Gastroenterology 18, 2012, 5653-5657


Immune-related GTPase M (IRGM1) regulates neuronal autophagy in a mouse model of stroke
He SY, Wang CD, Dong HY, Xia FC, Zhou H, Jiang XS, Pei CY, Ren H, Li HS , Li R, Xu HW
Autophagy 8, 2012, 1621-1627


Chaperone Activity of Small Heat Shock Proteins Underlies Therapeutic Efficacy in Experimental Autoimmune Encephalomyelitis
Kurnellas MP, Brownell SE, Su L, Malkovskiy AV, Rajadas J, Dolganov G, Chopra S, Schoolnik GK, Sobel RA, Webster J, Ousman SS, Becker RA, Steinman L, Rothbard JB
Journal of Biological Chemistry 287, 2012, 36423-36434


NOD2 Signaling and Role in Pathogenic Mycobacterium Recognition, Infection and Immunity
Deng WY, Xie JP
Cellular Physiology and Biochemistry 30, 2012, 953-963


Respiratory syncytial virus infection augments NOD2 signaling in an IFN-beta-dependent manner in human primary cells
Vissers M, Remijn T, Oosting M, de Jong DJ, Diavatopoulos DA, Hermans PWM, Ferwerda G
European Journal of Immunology 42, 2012, 2727-2735


Uptake and Persistence of Mycobacterium avium subsp paratuberculosis in Human Monocytes
Keown DA, Collings DA, Keenan JI
Infection and Immunity 80, 2012, 3768-3775


Ubiquitination and phosphorylation in the regulation of NOD2 signaling and NOD2-mediated disease
Tigno-Aranjuez JT, Abbott DW
Biochimica et Biophysica Acta-Molecular Cell Research 1823, 2012, 2022-2028


Autophagy Regulates IL-23 Secretion and Innate T Cell Responses through Effects on IL-1 Secretion
de Castro CP, Jones SA, Cheallaigh CN, Hearnden CA, Williams L, Winter J, Lavelle EC, Mills KHG, Harris J
Journal of Immunology 189, 2012, 4144-4153


Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases
Jeong E, Lee JY , Kim SJ, Choi J
Journal of Periodontal Research 47, 2012, 811-816


p40(phox) Expression Regulates Neutrophil Recruitment and Function during the Resolution Phase of Intestinal Inflammation
Conway KL, Goel G, Sokol H, Manocha M, Mizoguchi E, Terhorst C, Bhan AK, Gardet A, Xavier RJ
Journal of Immunology 189, 2012, 3631-3640


Pathway Analysis of a Genome-Wide Association Study of Ileal Crohn's Disease
Lee YH, Song GG
Dna and Cell Biology 31, 2012, 1549-1554


Lactase persistence, NOD2 status and Mycobacterium avium subsp paratuberculosis infection associations to Inflammatory Bowel Disease
Elguezabal N, Chamorro S, Molina E, Garrido JM, Izeta A, Rodrigo L, Juste RA
Gut Pathogens 4, 2012, Article Number: 6 DOI: 10.1186/1757-4749-4-6 Published: JUN 28 2012


Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes
Boisson-Dupuis S, Kong XF, Okada S, Cypowyj S, Puel A, Abel L, Casanova JL
Current Opinion in Immunology 24, 2012, 364-378


Systems Biology Analysis of Gene Expression during In Vivo Mycobacterium avium paratuberculosis Enteric Colonization Reveals Role for Immune Tolerance
Khare S, Lawhon SD, Drake KL, Nunes JES, Figueiredo JF, Rossetti CA, Gull T, Everts RE, Lewin HA, Galindo CL, Garner HR, Adams LG
Plos One 7, 2012, Article Number: e42127 DOI: 10.1371/journal.pone.0042127 Published: AUG 17 2012


The Innate Immune Protein Nod2 Binds Directly to MDP, a Bacterial Cell Wall Fragment
Grimes CL, Ariyananda LD, Melnyk JE, O'Shea EK
Journal of the American Chemical Society 134, 2012, 13535-13537


Role for mycobacterial infection in pathogenesis of primary biliary cirrhosis?
Smyk D, Rigopoulou EI, Zen Y, Abeles RD, Billinis C, Pares A, Bogdanos DP
World Journal of Gastroenterology 18, 2012, 4855-4865


Changed phagocytic activity and pattern of Fc gamma and complement receptors on blood monocytes in sarcoidosis
Dubaniewicz A, Typiak M, Wybieralska M, Szadurska M, Nowakowski S, Staniewicz-Panasik A, Rogoza K, Sternau A, Deeg P, Trzonkowski P
Human Immunology 73, 2012, 788-794


Serum anti-glycan antibody biomarkers for inflammatory bowel disease diagnosis and progression: A systematic review and meta-analysis
Kaul A, Hutfless S, Liu L, Bayless TM, Marohn MR, Li XH
Inflammatory Bowel Diseases 18, 2012, 1872-1884


Decreased RNA expression of interleukin 17A in skin of leprosy
da Motta-Passos I, Malheiro A, Naveca FG, Passos LFD, Cardoso CRD, Cunha MDS, Dos Santos MP, Silva GAV, Fraporti LS, de Paula L
European Journal of Dermatology 22, 2012, 488-494


Deficiency of N-acetylgalactosamine in O-linked oligosaccharides of IgA is a novel biologic marker for Crohn's disease
Inoue T, Iijima H, Tajiri M, Shinzaki S, Shiraishi E, Hiyama S, Mukai A, Nakajima S, Iwatani H, Nishida T, Mizushima T, Yasui T, Isaka Y, Kanto T, Tsujii M, Miyoshi E, Wada Y, Takehara T
Inflammatory Bowel Diseases 18, 2012, 1723-1734


Microbial Dysbiosis in Pediatric Patients with Crohn's Disease
Kaakoush NO, Day AS, Huinao KD, Leach ST, Lemberg DA, Dowd SE, Mitchell HM
Journal of Clinical Microbiology 50, 2012, 3258-3266


Microbiota Separation and C-reactive Protein Elevation in Treatment-naive Pediatric Granulomatous Crohn Disease
Kellermayer R, Mir SAV, Nagy-Szakal D, Cox SB, Dowd SE, Kaplan JL, Sun Y, Reddy S, Bronsky J , Winter HS
Journal of Pediatric Gastroenterology and Nutrition 55, 2012, 243-250


Macrolide Therapy in Chronic Inflammatory Diseases
Kwiatkowska B, Maslinska M
Mediators of Inflammation none, 2012, Article Number: 636157 DOI: 10.1155/2012/636157 Published: 2012


Modulation of inflammation by autophagy: consequences for Crohn's disease
Plantinga TS, Joosten LAB, van der Meer JWM, Netea MG
Current Opinion in Pharmacology 12, 2012, 497-502


Polymorphisms in Autophagy Genes and Susceptibility to Tuberculosis
Songane M, Kleinnijenhuis J, Alisjahbana B, Sahiratmadja E, Parwati I, Oosting M, Plantinga TS, Joosten LAB, Netea MG, Ottenhoff THM, van de Vosse E, van Crevel R
Plos One 7, 2012, Article Number: e41618 DOI: 10.1371/journal.pone.0041618 Published: AUG 6 2012


The c-Jun N-terminal Kinase (JNK)-binding Protein (JNKBP1) Acts as a Negative Regulator of NOD2 Protein Signaling by Inhibiting Its Oligomerization Process
Lecat A, Di Valentin E, Somja J, Jourdan S, Fillet M, Kufer TA, Habraken Y, Sadzot C, Louis E, Delvenne P, Piette J, Legrand-Poels S
Journal of Biological Chemistry 287, 2012, 29213-29226


Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of Fc gamma RIIB and dectin-1
Karsten CM, Pandey MK, Figge J, Kilchenstein R , Taylor PR, Rosas M, McDonald JU, Orr SJ, Berger M, Petzold D, Blanchard V, Winkler A, Hess C, Reid DM, Majoul IV, Strait RT, Harris NL, Kohl G, Wex E, Ludwig R, Zillikens D, Nimmerjahn F, Finkelman FD, Brown GD, Ehlers M, Kohl J
Nature Medicine 18, 2012, 1401-U146


Unusual B cell morphology in inflammatory bowel disease
Defendenti C, Grosso S, Atzeni F, Croce A, Senesi O, Saibeni S, Bollani S, Almasio PL, Bruno S, Sarzi-Puttini P
Pathology Research and Practice 208, 2012, 387-391


Mycobacterium avium subsp paratuberculosis in an Italian Cohort of Type 1 Diabetes Pediatric Patients
Bitti MLM, Masala S, Capasso F, Rapini N, Piccinini S, Angelini F, Pierantozzi A, Lidano R, Pietrosanti S, Paccagnini D, Sechi LA
Clinical & Developmental Immunology none, 2012, Article Number: 785262 DOI: 10.1155/2012/785262 Published: 2012


Practical immunoregulation: Neonatal immune response variation and prophylaxis of experimental food allergy in pigs
Wilkie BN, Rupa P, Schmied J
Veterinary Immunology and Immunopathology 148, 2012, 110-115


Molecular pathogenesis of bovine paratuberculosis and human inflammatory bowel diseases
Momotani E, Romona NM, Yoshihara K, Momotani Y , Hori M, Ozaki H, Eda S, Ikegami M
Veterinary Immunology and Immunopathology 148, 2012, 55-68


Current strategies for eradication of paratuberculosis and issues in public health
Juste RA
Veterinary Immunology and Immunopathology 148, 2012, 16-22


Mycobacterium avium ss paratuberculosis-associated Diseases Piecing the Crohn's Puzzle Together
Gitlin L, Borody TJ, Chamberlin W, Campbell J
Journal of Clinical Gastroenterology 46, 2012, 649-655


Mycobacterium avium Subspecies paratuberculosis in Crohn's Disease The Puzzle Continues
Das KM, Seril DN
Journal of Clinical Gastroenterology 46, 2012, 627-628


Nod2 improves barrier function of intestinal epithelial cells via enhancement of TLR responses
Hiemstra IH, Bouma G, Geerts D, Kraal G, den Haan JMM
Molecular Immunology 52, 2012, 264-272


IgG glycan hydrolysis by endoglycosidase S diminishes the proinflammatory properties of immune complexes from patients with systemic lupus erythematosus: A possible new treatment?
Lood C, Allhorn M, Lood R, Gullstrand B, Olin AI, Ronnblom L, Truedsson L, Collin M, Bengtsson AA
Arthritis and Rheumatism 64, 2012, 2698-2706


The Inositol Phosphatase SHIP-1 Inhibits NOD2-Induced NF-kappa B Activation by Disturbing the Interaction of XIAP with RIP2
Conde C, Rambout X, Lebrun M, Lecat A, Di Valentin E, Dequiedt F, Piette J, Gloire G, Legrand S
Plos One 7, 2012, Article Number: e41005 DOI: 10.1371/journal.pone.0041005 Published: JUL 17 2012


Microarray-based gene expression profiling reveals the mediators and pathways involved in the anti-arthritic activity of Celastrus-derived Celastrol
Yu H, Venkatesha SH, Moudgil KD
International Immunopharmacology 13, 2012, 499-506


T cells specific for lipid antigens
Mori L, De Libero G
Immunologic Research 53, 2012, 191-199


The rhapsody of NLRPs: master players of inflammation ... and a lot more
Zambetti LP, Laudisi F, Licandro G, Ricciardi-Castagnoli P, Mortellaro A
Immunologic Research 53, 2012, 78-90


A novel atherogenic epitope from Mycobacterium tuberculosis heat shock protein 65 enhances atherosclerosis in rabbit and LDL receptor-deficient mice
Zhang Y, Xiong QY, Hu XB, Sun YX, Tan XY, Zhang HY, Lu Y, Liu JJ
Heart and Vessels 27, 2012, 411-418


Pathogen Sensing by Nucleotide-binding Oligomerization Domain-containing Protein 2 (NOD2) Is Mediated by Direct Binding to Muramyl Dipeptide and ATP
Mo JY, Boyle JP , Howard CB, Monie TP, Davis BK, Duncan JA
Journal of Biological Chemistry 287, 2012, 23057-23067


Think Small: Zebrafish as a Model System of Human Pathology
Goldsmith JR, Jobin C
Journal of Biomedicine and Biotechnology -, 2012, Article Number: 817341 DOI: 10.1155/2012/817341 Published: 2012


Tuberculosis as a risk factor for systemic lupus erythematosus: results of a nationwide study in Taiwan
Lin YC, Liang SJ, Liu YH, Hsu WH, Shih CM, Sung FC, Chen W
Rheumatology International 32, 2012, 1669-1673


Nucleotide-Binding Oligomerization Domain 2 (Nod2) Is Dispensable for the Innate Immune Responses of Macrophages against Yersinia enterocolitica
Jeong YJ, Kim CH, Song EJ, Kang MJ, Kim JC, Oh SM, Lee KB, Park JH
Journal of Microbiology 50, 2012, 489-495


Evaluation of Immunogenicity of Purified Cell Wall-Associated 34 kDa Antigen of Mycobacterium avium subsp paratuberculosis Infection
Kavid N, Madani R, Hosseinkhani S, Mosavari N, Golchinfar F, Emami T, Keshavarz R
Hybridoma 31, 2012, 163-167


A commentary on current perspectives on Mycobacterium avium subsp paratuberculosis, Johne's disease and Crohn's disease: A review by Over et al. (2011)
Robertson R, Hill B, Cerf O, Jordan K, Venter P
Critical Reviews in Microbiology 38, 2012, 183-184


Engineering of the Saccharomyces cerevisiae yeast strain with multiple chromosome-integrated genes of human alpha-fetoprotein and its high-yield secretory production, purification, structural and functional characterization
Dudich E, Dudich I, Semenkova L, Benevolensky S , Morozkina E, Marchenko A, Zatcepin S, Dudich D, Soboleva G, Khromikh L, Roslovtceva O, Tatulov E
Protein Expression and Purification 84, 2012, 94-107


Crohn'S Disease Associated Nod2 Variants Show Differential Activation of Nf-Kappa B in Response to Auto-Signalling and Muramyl Dipeptide
Van Limbergen J, Soares F, Russell RK, Girardin S , Griffiths A, Philpott D
Gut 61, 2012, A221-A222


Interferon-gamma release assay versus tuberculin skin test prior to treatment with golimumab, a human anti-tumor necrosis factor antibody, in patients with rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis
Hsia EC, Schluger N, Cush JJ, Chaisson RE, Matteson EL, Xu S, Beutler A, Doyle MK, Hsu B, Rahman MU
Arthritis and Rheumatism 64, 2012, 2068-2077


A novel single nucleotide polymorphism within the NOD2 gene is associated with pulmonary tuberculosis in the Chinese Han, Uygur and Kazak populations
Zhao MY, Jiang F, Zhang WJ, Li FJ, Wei LL, Liu JY, Xue Y, Deng XL, Wu F, Zhang L, Zhang X, Zhang YX, Fan DP, Sun XJ, Jiang TT, Li JC
Bmc Infectious Diseases 12, 2012, Article Number: 91 DOI: 10.1186/1471-2334-12-91 Published: APR 14 2012


Anti-CD20 (rituximab) therapy for anti-IFN-gamma autoantibody-associated nontuberculous mycobacterial infection
Browne SK, Zaman R, Sampaio EP, Jutivorakool K, Rosen LB, Ding L, Pancholi MJ, Yang LM, Priel DL, Uzel G, Freeman AF, Hayes CE, Baxter R, Cohen SH, Holland SM
Blood 119, 2012, 3933-3939


Phenotypic and Transcriptomic Response of Auxotrophic Mycobacterium avium Subsp paratuberculosis leuD Mutant under Environmental Stress
Chen JW, Scaria J, Chang YF
Plos One 7, 2012, Article Number: e37884 DOI: 10.1371/journal.pone.0037884 Published: JUN 4 2012


Induction of matrix metalloproteinases and TLR2 and 6 in murine colon after oral exposure to Mycobacterium avium subsp paratuberculosis
Roderfeld M, Koc A, Rath T, Blocher S, Tschuschner A, Alcineden O, Fischer M, von Gerlach S, Goethe R, Eckelt E, Meens J, Bulte M, Basler T, Roeb E
Microbes and Infection 14, 2012, 545-553


Mycobacterium avium paratuberculosis in Italy: Commensal or emerging human pathogen?
Pistone D, Marone P, Pajoro M, Fabbi M, Vicari N, Daffara S, la Valle C, Gabba S, Sassera D , Verri A, Montagna M, Epis S, Monti C, Strada EG, Grazioli V, Arrigoni N, Giacosa A, Bandi C
Digestive and Liver Disease 44, 2012, 461-465


Occurrence of Mycobacterium avium subsp paratuberculosis in milk at dairy cattle farms: A systematic review and meta-analysis
Okura H, Toft N , Nielsen SS
Veterinary Microbiology 157, 2012, 253-263


Rapid and Sensitive Detection of an Intracellular Pathogen in Human Peripheral Leukocytes with Hybridizing Magnetic Relaxation Nanosensors
Kaittanis C, Boukhriss H, Santra S, Naser SA, Perez JM
Plos One 7, 2012, Article Number: e35326 DOI: 10.1371/journal.pone.0035326 Published: APR 9 2012


The Nucleotide Synthesis Enzyme CAD Inhibits NOD2 Antibacterial Function in Human Intestinal Epithelial Cells
Richmond AL, Kabi A, Homer CR, Marina-Garcia N, Nickerson KP, Nesvizhskii AI, Sreekumar A, Chinnaiyan AM, Nunez G, McDonald C
Gastroenterology 142, 2012, 1483-1492 e6


NMR Characterization of Immunoglobulin G Fc Glycan Motion on Enzymatic Sialylation
Barb AW, Meng L , Gao ZW, Johnson RW, Moremen KW, Prestegard JH
Biochemistry 51, 2012, 4618-4626


Regulation of intracrine production of 1,25-dihydroxyvitamin D and its role in innate immune defense against infection
White JH
Archives of Biochemistry and Biophysics 523, 2012, 58-63


Novel roles for the IgG Fc glycan
Anthony RM, Wermeling F, Ravetch JV
Annals of the New York Academy of Sciences, Book Series 1253, 2012, 170-180


Galectins in acute and chronic inflammation
Liu FT, Yang RY , Hsu DK
Annals of the New York Academy of Sciences, Book Series 1253, 2012, 80-91


Interleukin-2, Interleukin-7, T cell-mediated autoimmunity, and N-glycosylation
Grigorian A, Mkhikian H, Demetriou M
Annals of the New York Academy of Sciences, Book Series 1253, 2012, 49-57


Siglecs as sensors of self in innate and adaptive immune responses
Paulson JC, Macauley MS, Kawasaki N
Annals of the New York Academy of Sciences, Book Series 1253, 2012, 37-48


Glycobiology of immune responses
Rabinovich GA, van Kooyk Y, Cobb BA
Annals of the New York Academy of Sciences, Book Series 2012, 1-15


Clinical utility of anti-glycan antibodies in pediatric crohn's disease in comparison with an adult cohort
Rieder F, Hahn P, Finsterhoelzl L, Schleder S , Wolf A, Dirmeier A, Lopez R, Shen B, Rogler G, Klebl F, Lang TM
Inflammatory Bowel Diseases 18, 2012, 1221-1231


MIP-3 alpha Expression in Macrophages Is NOD Dependent
Hausmann M, Zeitler C, Weber A, Krebs M, Kellermeier S, Rosenstiel P, de Valliere C, Kosovac K, Fried M, Holler E, Rogler G
Digestion 85, 2012, 192-201


Potential T cell epitopes of Mycobacterium tuberculosis that can instigate molecular mimicry against host: implications in autoimmune pathogenesis
Chodisetti SB, Rai PK, Gowthaman U, Pahari S, Agrewala JN
Bmc Nephrology 13, 2012, Article Number: 13 DOI: 10.1186/1471-2172-13-13 Published: MAR 21 2012


Inflammatory lesions of the orbit: a single paediatric rheumatology centre experience
Boulter EL, Eleftheriou D, Sebire NJ, Edelsten C, Brogan PA
Rheumatology 51, 2012, 1070-1075


Dysfunction of Natural Killer T Cells in Patients with Active Mycobacterium tuberculosis Infection
Kee SJ, Kwon YS , Park YW, Cho YN, Lee SJ, Kim TJ, Lee SS, Jang HC, Shin MG, Shin JH, Suh SP, Ryang DW
Infection and Immunity 80, 2012, 2100-2108


IL-23 in Infections, Inflammation, Autoimmunity and Cancer: Possible Role in HIV-1 and AIDS
Yannam GR, Gutti T, Poluektova LY
Journal of Neuroimmune Pharmacology 7, 2012, 95-112


Polymorphisms of NOD2 and the risk of tuberculosis: a validation study in the Chinese population
Pan H, Dai Y, Tang S, Wang J
International Journal of Immunogenetics 39, 2012, 233-240


Yersinia pseudotuberculosis Effector YopJ Subverts the Nod2/RICK/TAK1 Pathway and Activates Caspase-1 to Induce Intestinal Barrier Dysfunction
Meinzer U, Barreau F, Esmiol-Welterlin S, Jung C, Villard C, Leger T, Ben-Mkaddem S, Berrebi D, Dussaillant M, Alnabhani Z, Roy M, Bonacorsi S, Wolf-Watz H, Perroy J, Ollendorff V, Hugot JP
Cell Host & Microbe 11, 2012, 337-351


Crohn's disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy
Scharl M, Mwinyi J, Fischbeck A, Leucht K, Eloranta JJ, Arikkat J, Pesch T, Kellermeier S, Mair A, Kullak-Ublick GA, Truninger K, Noreen F, Regula J, Gaj P, Pittet V, Mueller C, Hofmann C, Fried M, Mccole DF, Rogler G
Inflammatory Bowel Diseases 18, 2012, 900-912


Altered Oligosaccharide Structures Reduce Colitis Induction in Mice Defective in beta-1,4-Galactosyltransferase
Shinzaki S, Iijima H, Fujii H, Kuroki E, Tatsunaka N, Inoue T, Nakajima S, Egawa S, Kanto T, Tsujii M, Morii E, Takeishi S, Asano M, Takehara T, Hayashi N, Miyoshi E
Gastroenterology 142, 2012, 1172-1182


Immuno-inhibitory PD-L1 can be induced by a Peptidoglycan/NOD2 mediated pathway in primary monocytic cells and is deficient in Crohn's patients with homozygous NOD2 mutations
Hewitt RE, Pele LC, Tremelling M, Metz A, Parkes M, Powell JJ
Clinical Immunology 143, 2012, 162-169


Mycobacterium avium paratuberculosis and Crohn's Disease: An association requiring more research
Kuenstner JT
Journal of Crohns & Colitis 6, 2012, 393


Much is still to be learned about pathogenic Mycobacteria Reply
Van Kruiningen HJ
Journal of Crohns & Colitis 6, 2012, 392


Much is still to be learned about pathogenic Mycobacteria
Chamberlin WM
Journal of Crohns & Colitis 6, 2012, 390-391


The image of mass destruction inevitably leads to intellectual mass distraction
Chiodini RJ
Journal of Crohns & Colitis 6 , 2012, 388-389


IBD-what role do Proteobacteria play?
Mukhopadhya I, Hansen R, El-Omar EM, Hold GL
Nature Reviews Gastroenterology & Hepatology 9, 2012, 219-230


Peptidoglycan as Nod1 ligand: fragment structures in the environment, chemical synthesis, and their innate immunostimulation
Fujimoto Y, Pradipta AR, Inohara N, Fukase K
Natural Product Reports 29, 2012, 568-579


Macrophages participate in IL-17-mediated inflammation
Barin JG, Baldeviano GC, Talor MV, Wu L, Ong S, Quader F, Chen P, Zheng DF, Caturegli P, Rose NR, Cihakova D
European Journal of Immunology 42, 2012, 726-736


Role of biological therapy for inflammatory bowel disease in developing countries
Rogler G, Bernstein CN, Sood A, Goh KL, Yamamoto-Furusho JK, Abbas Z, Fried M
Gut 61, 2012, 706-712


Ergothioneine: antioxidant potential, physiological function and role in disease
Cheah IK, Halliwell B
Biochimica et Biophysica Acta-Molecular Basis of Disease 1822, 2012, 784-793


A case of mistaken identity: HSPs are no DAMPs but DAMPERs
Van Eden W, Spiering R, Broere F, van der Zee R
Cell Stress & Chaperones 17, 2012, 281-292


Tumour necrosis factor-mediated macrophage activation in the target organ is critical for clinical manifestation of uveitis
Khera TK, Copland DA, Boldison J, Lait PJP, Szymkowski DE, Dick AD, Nicholson LB
Clinical and Experimental Immunology 168, 2012, 165-177


Preparation, crystallization and preliminary X-ray diffraction studies of the glycosylated form of human interleukin-23
Shirouzono T, Chirifu M, Nakamura C, Yamagata Y, Ikemizu S
Acta Crystallographica Section F-Structural Biology and Crystallization Communications 68 , 2012, 432-435


Association study of CARD8 (p.C10X) and NLRP3 (p.Q705K) variants with rheumatoid arthritis in French and Tunisian populations
Ben Hamad M, Cornelis F, Marzouk S, Chabchoub G, Bahloul Z, Rebai A, Fakhfakh F, Ayadi H, Petit-Teixeira E, Maalej A
International Journal of Immunogenetics 39, 2012, 131-136


Redundant and Antagonistic Functions of Galectin-1,-3, and-8 in the Elicitation of T Cell Responses
Tribulatti MV, Figini MG, Carabelli J, Cattaneo V , Campetella O
Journal of Immunology 188, 2012, 2991-2999


Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer
Rabinovich GA, Croci DO
Immunity 36, 2012, 322-335


Nod2: a key regulator linking microbiota to intestinal mucosal immunity
Biswas A, Petnicki-Ocwieja T, Kobayashi KS
Journal of Molecular Medicine-Jmm 90, 2012, 15-24


Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner
Oomizu S, Arikawa T, Niki T, Kadowaki T, Ueno M, Nishi N, Yamauchi A, Hirashima M
Clinical Immunology 143, 2012, 51-58


Resveratrol has antiinflammatory and antifibrotic effects in the peptidoglycan-polysaccharide rat model of Crohn's disease
Rahal K, Schmiedlin-Ren P, Adler J, Dhanani M, Sultani V, Rittershaus AC, Reingold L, Zhu J, McKenna BJ, Christman GM, Zimmermann EM
Inflammatory Bowel Diseases 18 , 2012, 613-623


Identification and Characterization of a Spore-Like Morphotype in Chronically Starved Mycobacterium avium Subsp Paratuberculosis Cultures
Lamont EA, Bannantine JP, Armien A, Ariyakumar DS , Sreevatsan S
Plos One 7, 2012, Article Number: e30648 DOI: 10.1371/journal.pone.0030648 Published: JAN 24 2012


In vivo priming of IL-17(+) uveitogenic T cells is enhanced by Toll ligand receptor (TLR)2 and TLR4 agonists via gamma delta T cell activation
Zuo AJ, Liang DC, Shao H, Born WK, Kaplan HJ, Sun DM
Molecular Immunology 50, 2012, 125-133


Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors
Deretic V
Current Opinion in Immunology 24, 2012, 21-31


Vitamin D metabolism and signaling in the immune system
White JH
Reviews in Endocrine & Metabolic Disorders 13, 2012, 21-29


Crohn's disease and Mycobacterium avium subsp paratuberculosis: The need for a study is long overdue
Davis WC, Madsen-Bouterse SA
Veterinary Immunology and Immunopathology 145, 2012, 1-6


Innate Immunity: Ignored for Decades, but Not Forgotten
Modlin RL
Journal of Investigative Dermatology 132, 2012, 882-886


Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis
Zhu B, Trikudanathan S, Zozulya AL, Sandoval-Garcia C, Kennedy JK, Atochina O, Norberg T, Castagner B, Seeberger P, Fabry Z, Harn D, Khoury SJ, Guleria I
Clinical Immunology 142, 2012, 351-361


The role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease
Ingersoll SA, Ayyadurai S, Charania MA, Laroui H, Yan YT, Merlin D
American Journal of Physiology-Gastrointestinal and Liver Physiology 302, 2012, G484-G492


Examining host-microbial interactions through the lens of NOD: From plants to mammals
Robertson SJ, Rubino SJ, Geddes K, Philpott DJ
Seminars in Immunology 24, 2012, 9-16


Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients
Castro I, Aguilera S, Brockhausen I, Alliende C, Quest AFG, Molina C, Urzua U, Mandel U, Bahamondes V, Barrera MJ, Sanchez M, Gonzalez S, Hermoso M, Leyton C, Gonzalez MJ
Rheumatology 51, 2012, 482-490


Replication of Crohn's disease-associated AIEC within macrophages is dependent on TNF-alpha secretion
Bringer MA, Billard E, Glasser AL, Colombel JF , rfeuille-Michaud A
Laboratory Investigation 92, 2012, 411-419


Autophagy, nutrition and immunology
Cuervo AM, Macian F
Molecular Aspects of Medicine 33, 2012, 2-13


Adjuvant Immunotherapy of Experimental Autoimmune Encephalomyelitis: Immature Myeloid Cells Expressing CXCL10 and CXCL16 Attract CXCR3(+)CXCR6(+) and Myelin-Specific T Cells to the Draining Lymph Nodes Rather Than the Central Nervous System
O'Connor RA, Li XJ, Blumerman S, Anderton SM, Noelle RJ, Dalton DK
Journal of Immunology 188, 2012, 2093-2101


Biotin sulfone tagged oligomannosides as immunogens for eliciting antibodies against specific mannan epitopes
Despras G, Robert R, Sendid B, Machez E, Poulain D, Mallet JM
Bioorganic & Medicinal Chemistry 20, 2012, 1817-1831


Galectin-1 research in T cell immunity: Past, present and future
Cedeno-Laurent F, Dimitroff CJ
Clinical Immunology 142, 2012, 107-116


Effects of Single Genetic Damage in Carbohydrate-Recognizing Proteins in Mouse Serum N-Glycan Profile Revealed by Simple Glycotyping Analysis
Amano M, Hashimoto R, Nishimura SI
Chembiochem 13, 2012, 451-464


Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion
Thurston TLM, Wandel MP, von Muhlinen N, Foeglein A, Randow F
Nature 482, 2012, 414-U1515


Crohn's disease and the mycobacterioses: A quarter century later. Causation or simple association?
Chiodini RJ, Chamberlin WM, Sarosiek J, McCallum RW
Critical Reviews in Microbiology 38, 2012, 52-93


Chronic Nod2 Stimulation Potentiates Activating Transcription Factor 3 and Paradoxical Superinduction of Epithelial Proinflammatory Chemokines by Mucoactive Ribotoxic Stressors via RNA-Binding Protein Human Antigen R
Park SH, Choi HJ, Do KH, Yang H, Kim J, Moon Y
Toxicological Sciences 125, 2012, 116-125


Oily adjuvants and autoimmunity: now time for reconsideration?
Whitehouse M
Lupus 21, 2012, 217-222


Gastrointestinal infection as a trigger for inflammatory bowel disease
Mann EA, Saeed SA
Current Opinion in Gastroenterology 28, 2012, 24-29


Viral Infection Augments Nod1/2 Signaling to Potentiate Lethality Associated with Secondary Bacterial Infections
Kim YG, Park JH, Reimer T, Baker DP, Kawai T, Kumar H, Akira S, Wobus C, Nunez G
Cell Host & Microbe 9, 16-6-2011, 496-507


The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challenge
Yu H, Lu CW, Tan MT, Moudgil KD
Arthritis Research & Therapy 13, 2011, Article Number: R143 DOI: 10.1186/ar3457 Published: 2011


Inverse vaccination with islet autoantigens to halt progression of autoimmune diabetes
Hinke SA
Drug Development Research 72, 2011, 788-804


Where are the weapons of mass destruction - the Mycobacterium paratuberculosis in Crohn's disease?
Van Kruiningen HJ
Journal of Crohns & Colitis 5, 2011, 638-644


Interaction between Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium avium subspecies paratuberculosis with the enteric glia and microglial cells
Cannas S, MoliCotti P, Bua A, Usai D, Sechi LA, Scanu AM, Blasi E, Zanetti S
Gut Pathogens 3, 2011, Article Number: 19 DOI: 10.1186/1757-4749-3-19 Published: DEC 9 2011


Mycobacterium avium subsp paratuberculosis infection in slaughtered domestic pigs for consumption detected by molecular methods
Miranda C, Matos M, Pires I, Ribeiro P, Alvares S, Vieira-Pinto M, Coelho AC
Food Research International 44, 2011, 3276-3277


Blau syndrome
Punzi L, Gava A , Galozzi P, Sfriso P
Best Practice & Research in Clinical Rheumatology 25, 2011, 703-714


Thalidomide induces mucosal healing in Crohn's disease: Case report
Leite MR, Santos SS, Lyra AC, Mota J, Santana GO
World Journal of Gastroenterology 17, 2011, 5028-5031


Immune-mediated adverse effects of biologicals used in the treatment of rheumatic diseases
Borchers AT, Leibushor N, Cheema GS, Naguwa SM, Gershwin ME
Journal of Autoimmunity 37, 2011, 273-288


Mycobacterium paratuberculosis and autism: Is this a trigger?
Dow CT
Medical Hypotheses 77, 2011, 977-981


TLR-dependent T cell activation in autoimmunity
Mills KHG
Nature Reviews Immunology 11, 2011, 807-822


Immune reconstitution inflammatory syndrome
Breton G
Bulletin de l Academie Nationale de Medecine 195, 2011, 561-575


Nod2 Downregulates TLR2/1 Mediated IL1 beta Gene Expression in Mouse Peritoneal Macrophages
Dahiya Y, Pandey RK, Sodhi A
Plos One 6, 2011, Issue 11


Interaction between glycans and the immune system: do glycans play a role in Crohn's disease pathogenesis?
Baram L, Spektor L, Elad H, Halpern Z, Guzner-Gur H, Dotan I
Immunology 135, 2011, 156


Peptidoglycan Recognition Protein Pglyrp2 Protects Mice from Psoriasis-like Skin Inflammation by Promoting Regulatory T Cells and Limiting Th17 Responses
Park SY, Gupta D, Hurwich R, Kim CH, Dziarski R
Journal of Immunology 187, 2011, 5813-5823


Biologics and Infections: Lessons from Tumor Necrosis Factor Blocking Agents
Wallis RS
Infectious Disease Clinics of North America 25, 2011, 895-+


Association of Toll-like receptor 10 and susceptibility to Crohn's disease independent of NOD2
Abad C, Gonzalez-Escribano MF, az-Gallo LM, Lucena-Soto JM, Marquez JL, Leo E, Crivell C, Gomez-Garcia M, Martin J, Nunez-Roldan A, Garcia-Lozano JR
Genes and Immunity 12, 2011, 635-642


Correlation of Mycobacterium avium subsp paratuberculosis counts in gastrointestinal tract, muscles of the diaphragm and the masseter of dairy cattle and potential risk for consumers
Pribylova R, Slana I, Kralik P, Kralova A, Babak V, Pavlik I
International Journal of Food Microbiology 151, 2011, 314-318


Intracellular bacteria can cause EAE in SJL mice or modify self-specific T cell repertoire
Nicolo C, Di Sante G, Migliara G, Valentini MG, Piermattei A, Delogu G, Ria F
Journal of the Neurological Sciences 311, 2011, 103-106


Impaired Dendritic Cell Proinflammatory Cytokine Production in Psoriatic Arthritis
Wenink MH, Santegoets KCM, Butcher J, van Bon L, Lamers-Karnebeek FGM, van den Berg WB, van Riel PLCM, McInnes IB, Radstake TRDJ
Arthritis and Rheumatism 63, 2011, 3313-3322


Food Safety Concerns Regarding Paratuberculosis
Collins MT
Veterinary Clinics of North America-Food Animal Practice 27, 2011, 631-+


Antibodies Recognizing Mycobacterium avium paratuberculosis Epitopes Cross-React with the Beta-Cell Antigen ZnT8 in Sardinian Type 1 Diabetic Patients
Masala S, Paccagnini D, Cossu D, Brezar V, Pacifico A, Ahmed N, Mallone R, Sechi LA
Plos One 6, 2011,


Primary treatment of Crohn's disease: combined antibiotics taking center stage
Chamberlin W, Borody TJ, Campbell J
Expert Review of Clinical Immunology 7, 2011, 751-760


Comparison of two decontamination procedures, three culture media, and real time-PCR assay for the detection of Mycobacterium avium subsp paratuberculosis (MAP) from artificially contaminated raw sausage
Akineden O, Fernandez-Silva JA, Weirich S, Abdulmawjood A, Bulte M
Archiv fur Lebensmittelhygiene 62, 2011, 150-156


H. pylori exploits and manipulates innate and adaptive immune cell signaling pathways to establish persistent infection
Muller A, Oertli M, Arnold IC
Cell Communication and Signaling 9, 2011,


Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
Rivas MA, Beaudoin M, Gardet A, Stevens C, Sharma Y, Zhang CK, Boucher G, Ripke S, Ellinghaus D, Burtt N, Fennell T, Kirby A, Latiano A, Goyette P, Green T, Halfvarson J, Haritunians T, Korn JM, Kuruvilla F, Lagace C, Neale B, Lo KS, Schumm P, Torkvist L, Dubinsky MC, Brant SR, Silverberg MS, Duerr RH, Altshuler D, Gabriel S, Lettre G, Franke A, D'Amato M, McGovern DPB, Cho JH, Rioux JD, Xavier RJ, Daly MJ
Nature Genetics 43, 2011, 1066-1U50


Involvement of Mycobacterium avium subspecies Paratuberculosis in TNF-alpha Production from Macrophage: Possible Link Between MAP and Immune Response in Crohn's Disease
Nakase H, Tamaki H, Matsuura M, Chiba T, Okazaki K
Inflammatory Bowel Diseases 17, 2011, Pages: E140-E142 DOI: 10.1002/ibd.21750 Published: NOV 2011


Autophagy and cytokines
Harris J
Cytokine 56, 2011, 140-144


Tlr2: A Crossroads Between Infections and Autoimmunity?
Borrello S, Nicolo C, Delogu G, Pandolfi F, Ria F
International Journal of Immunopathology and Pharmacology 24, 2011, 549-556


High prevalence of Mycobacterium avium subspecies paratuberculosis ('Indian bison type') in animal attendants suffering from gastrointestinal complaints who work with goat herds endemic for Johne's disease in India
Singh AV, Singh SV, Singh PK, Sohal JS, Singh MK
International Journal of Infectious Diseases 15, 2011, E677-E683


Human C-type Lectin Domain Family 4, Member C (CLEC4C/BDCA-2/CD303) Is a Receptor for Asialo-galactosyl-oligosaccharides
Riboldi E, Daniele R, Parola C, Inforzato A, Arnold PL, Bosisio D, Fremont DH, Bastone A, Colonna M, Sozzani S
Journal of Biological Chemistry 286, 2011, 35329-35333


Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response
Kleinnijenhuis J, Oosting M, Plantinga TS, van der Meer JWM, Joosten LAB, Crevel RV , Netea MG
Immunology 134, 2011, 341-348


Galectins and microenvironmental niches during hematopoiesis
Rabinovich GA, Vidal M
Current Opinion in Hematology 18, 2011, 443-451


Coupling pathogen recognition to innate immunity through glycan-dependent mechanisms
Davicino RC, Elicabe RJ, Di Genaro MS, Rabinovich GA
International Immunopharmacology 11, 2011, 1457-1463


Identification of Inhibitors of NOD1-Induced Nuclear Factor-kappa B Activation
Khan PM, Correa RG, Divlianska DB, Peddibhotla S, Sessions EH, Magnuson G, Brown B, Suyama E, Yuan HB, Mangravita-Novo A, Vicchiarelli M, Su Y, Vasile S, Smith LH, Diaz PW, Reed JC, Roth GP
Acs Medicinal Chemistry Letters 2, 2011, 780-785


Immunomodulation and Regeneration of Islet Beta Cells by Cytokines in Autoimmune Type 1 Diabetes
Singh B, Nikoopour E, Huszarik K, Elliott JF, Jevnikar AM
Journal of Interferon and Cytokine Research 31, 2011, 711-719


Intestinal tuberculosis: a diagnostic challenge - case report and review of the literature
Giouleme O, Paschos P, Katsaros M, Papalexi F, Karabatsou S, Masmanidou M, Koliouskas D
European Journal of Gastroenterology & Hepatology 23, 2011, 1074-1077


Rapid growing mycobacteria and TNF-alpha blockers: case report of a fatal lung infection with Mycobacterium abscessus in a patient treated with infliximab, and literature review
Besada E
Clinical and Experimental Rheumatology 29, 2011, 705-707


From gut microflora imbalance to mycobacteria infection: is there a relationship with chronic intestinal inflammatory diseases?
Tomasello G, Bellavia M, Palumbo VD, Gioviale MC , Damiani P, Lo Monte AI
Annali Italiani di Chirurgia 82, 2011, 361-368


Differential Effects of Peptidoglycan Recognition Proteins on Experimental Atopic and Contact Dermatitis Mediated by Treg and Th17 Cells
Park SY, Gupta D, Kim CH, Dziarski R
Plos One 6, 2011, Issue: 9, Article Number: e24961,DOI: 10.1371/journal.pone.0024961,Published: SEP 16 2011


MAP3738c and MptD are specific tags of Mycobacterium avium subsp paratuberculosis infection in type I diabetes mellitus
Cossu A, Rosu V , Paccagnini D, Cossu D, Pacifico A, Sechi LA
Clinical Immunology 141, 2011, 49-57


Evaluation of the role of erythropoietin and methotrexate in multiple sclerosis
Dasgupta S, Mazumder B, Ramani YR, Bhattacharyya SP, Das MK
Indian Journal of Pharmacology 43, 2011, 512-515


Increased Levels of Anti-Glycan Antibodies in Patients with Cystic Fibrosis
Hirche TO, Stein J, Hirche H, Hausmann J, Wagner TO, Behrens F, Schroder O
European Journal of Medical Research 16, 2011, 385-390


Fecal Detection of Mycobacterium avium Paratuberculosis Using the IS900 DNA Sequence in Crohn's Disease and Ulcerative Colitis Patients and Healthy Subjects
Tuci A, Tonon F , Castellani L, Sartini A, Roda G, Marocchi M, Caponi A, Munarini A, Rosati G, Ugolini G, Fuccio L, Scagliarini M, Bazzoli F, Belluzzi A
Digestive Diseases and Sciences 56, 2011, 2957-2962


The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease
Billmann-Born S, Lipinski S, Bock J, Till A, Rosenstiel P, Schreiber S
European Journal of Cell Biology 90, 2011, 593-602


Intracellular sensors of extracellular bacteria
Clarke TB, Weiser JN
Immunological Reviews 243, 2011, 9-25


The machinery of Nod-like receptors: refining the paths to immunity and cell death
Saleh M
Immunological Reviews 243, 2011, 235-246


NKT Cells Are Required for Complete Freund's Adjuvant-Mediated Protection from Autoimmune Diabetes
Lee IF, van den Elzen P, Tan RS, Priatel JJ
Journal of Immunology 187, 2011, 2898-2904


Cutting Edge: Crohn's Disease-Associated Nod2 Mutation Limits Production of Proinflammatory Cytokines To Protect the Host from Enterococcus faecalis-Induced Lethality
Kim YG, Shaw MH , Warner N, Park JH, Chen F, Ogura Y, Nunez G
Journal of Immunology 187, 2011, 2849-2852


Vitamin D3: a helpful immuno-modulator
Di Rosa M, Malaguarnera M, Nicoletti F, Malaguarnera L
Immunology 134, 2011, 123-139


Genetics of infectious diseases: hidden etiologies and common pathways
Orlova M, Di Pietrantonio T, Schurr E
Clinical Chemistry and Laboratory Medicine 49, 2011, 1427-1437


Genetic susceptibility to infections
Ott SJ, Schreiber S
Internist 52, 2011, 1053-+


L-Ala-gamma-D-Glu-meso-diaminopimelic Acid (DAP) Interacts Directly with Leucine-rich Region Domain of Nucleotide-binding Oligomerization Domain 1, Increasing Phosphorylation Activity of Receptor-interacting Serine/Threonine-protein Kinase 2 and Its Interaction with Nucleotide-binding Oligomerization Domain 1
Laroui H, Yan YT, Narui Y, Ingersoll SA, Ayyadurai S, Charania MA, Zhou F, Wang BH, Salaita K, Sitaraman SV, Merlin D
Journal of Biological Chemistry 286, 2011, 31003-31013


Increased expression of distinct galectins in multiple sclerosis lesions
Stancic M, van Horssen J, Thijssen VL, Gabius HJ, van der Valk P, Hoekstra D, Baron W
Neuropathology and Applied Neurobiology 37, 2011, 654-671


ATG16L1 polymorphisms are associated with NOD2-induced hyperinflammation
Plantinga TS, Joosten LAB, Netea MG
Autophagy 7, 2011, 1074-1075


Nod-like receptors in intestinal homeostasis, inflammation, and cancer
Werts C, Rubino S, Ling A, Girardin SE, Philpott DJ
Journal of Leukocyte Biology 90, 2011, 471-482


Cooperative Regulation of NOTCH1 Protein-Phosphatidylinositol 3-Kinase (PI3K) Signaling by NOD1, NOD2, and TLR2 Receptors Renders Enhanced Refractoriness to Transforming Growth Factor-beta (TGF-beta)- or Cytotoxic T-lymphocyte Antigen 4 (CTLA-4)-mediated Impairment of Human Dendritic Cell Maturation
Ghorpade DS, Kaveri SV, Bayry J, Balaji KN
Journal of Biological Chemistry 286, 2011, 31347-31360


Nod2 is essential for temporal development of intestinal microbial communities
Rehman A, Sina C, Gavrilova O, Hasler R, Ott S, Baines JF, Schreiber S, Rosenstiel P
Gut 60, 2011, 1354-1362


Down-Regulated NOD2 by Immunosuppressants in Peripheral Blood Cells in Patients with SLE Reduces the Muramyl Dipeptide-Induced IL-10 Production
Yu SL, Wong CK, Wong PTY, Chen DP, Szeto CC, Li EK, Tam LS
Plos One 6, 2011, Article Number: e23855 DOI: 10.1371/journal.pone.0023855 Published: AUG 19 2011


beta 2-Adrenergic agonists bias TLR-2 and NOD2 activated dendritic cells towards inducing an IL-17 immune response
Manni M, Granstein RD, Maestroni G
Cytokine 55, 2011, 380-386


Distinct Roles for Nod2 Protein and Autocrine Interleukin-1 beta in Muramyl Dipeptide-induced Mitogen-activated Protein Kinase Activation and Cytokine Secretion in Human Macrophages
Hedl M, Abraham C
Journal of Biological Chemistry 286, 2011, 26440-26449


Macrophages from IBD patients exhibit defective tumour necrosis factor-alpha secretion but otherwise normal or augmented pro-inflammatory responses to infection
Campos N, Magro F, Castro AR, Cabral J, Rodrigues P, Silva R, Appelberg R, Rodrigues S, Lopes S, Macedo G, Sarmento A
Immunobiology 216, 2011, 961-970


NOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease
Strober W, Watanabe T
Mucosal Immunology 4, 2011, 484-495


Mycobacterium bovis Bacillus Calmette-Guerin Killed by Extended Freeze-Drying Reduces Colitis in Mice
Lagranderie M, Kluge C, Kiefer-Biasizzo H, Abolhassani M, Nahori MA, Fitting C, Huerre M, Bandeira A, Bercovier H, Marchal G
Gastroenterology 141, 2011, 642-U750


Cutaneous Mycobacterial Spindle Cell Pseudotumor: A Potential Mimic of Soft Tissue Neoplasms
Yeh I, George E , Jokinen CH
American Journal of Dermatopathology 33, 2011, E66-E69


Association between NOD2/CARD15 polymorphisms and coronary artery disease: a case-control study
Galluzzo S, Patti G, Dicuonzo G, Di Sciascio G, Tonini G, Ferraro E, Spoto C, Campanale R, Zoccoli A, Angeletti S
Human Immunology 72, 2011, 636-640


Autolytic Mycobacterium leprae Hsp65 fragments may act as biological markers for autoimmune diseases
Parada CA, Portaro F, Marengo EB, Klitzke CF, Vicente EJ, Faria M, Sant'Anna OA, Fernandes BL
Microbial Pathogenesis 51, 2011, 268-276


NOD2 Deficiency Results in Increased Susceptibility to Peptidoglycan-Induced Uveitis in Mice
Rosenzweig HL, Galster K, Vance EE, Ensign-Lewis J, Nunez G, Davey MP, Rosenbaum JT
Investigative Ophthalmology & Visual Science 52, 2011, 4106-4112


Exploring the Zoonotic Potential of Mycobacterium avium Subspecies paratuberculosis through Comparative Genomics
Wynne JW, Bull TJ, Seemann T, Bulach DM, Wagner J, Kirkwood CD, Michalski WP
Plos One 6, 2011, Article Number: e22171 DOI: 10.1371/journal.pone.0022171 Published: JUL 22 2011


The role of bacteria and pattern-recognition receptors in Crohn's disease
Man SM, Kaakoush NO, Mitchell HM
Nature Reviews Gastroenterology & Hepatology 8, 2011, 152-168


Mycobacterium avium Subspecies paratuberculosis in Children with Early-onset Crohn's Disease: A Longitudinal Follow-up Study
Wagner J, Sim W , Bishop RF, Catto-Smith AG, Cameron DJS, Kirkwood CD
Inflammatory Bowel Diseases 17, 2011, 1825-1826


Antimicrobial Peptide Response to Blood Translocation of Bacterial DNA in Crohn's Disease Is Affected by NOD2/CARD15 Genotype
Gutierrez A, Holler E, Zapater P, Sempere L, Jover R, Perez-Mateo M, Schoelmerich J, Such J, Wiest R, Frances R
Inflammatory Bowel Diseases 17, 2011, 1641-1650


NKT Cell Ligand Recognition Logic: Molecular Basis for a Synaptic Duet and Transmission of Inflammatory Effectors
Joyce S, Girardi E, Zajonc DM
Journal of Immunology 187, 1-8-2011, 1081-1089


Bacteria as Trigger for Chronic Gastrointestinal Disorders
Marteau P, Chaput U
Digestive Diseases 29, 2011, 166-171


Functional Expression of NOD2 in Freshly Isolated Human Peripheral Blood gamma delta T Cells
Marischen L, Wesch D, Oberg HH, Rosenstiel P, Trad A, Shomali M, Grotzinger J, Janssen O, Tchikov V, Schutze S, Kabelitz D
Scandinavian Journal of Immunology 74, 2011, 126-134


Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide
Fernandez EM, Valenti V, Rockel C, Hermann C, Pot B, Boneca IG, Grangette C
Gut 60, 2011, 1050-1059


Regulation of Mycobacterium-Specific Mononuclear Cell Responses by 25-Hydroxyvitamin D-3
Nelson CD, Nonnecke BJ, Reinhardt TA, Waters WR , Beitz DC, Lippolis JD
Plos One 6, 2011, Article Number: e21674 Published: JUN 28 2011


Oral administration of Lactococcus lactis delivered heat shock protein 65 attenuates atherosclerosis in low-density lipoprotein receptor-deficient mice
Hou J, Lu Y, Liu HY, Ma YJ, Xing Y, Zhang Y, Li TM, Cao RY, Jin L, Wu J, Zong L, Liu JJ
Vaccine 29, 2011, 4102-4109


Mycobacterium avium subsp paratuberculosis in powdered infant milk: F57 competitive real time PCR
Hruska K, Slana I, Kralik P, Pavlik I
Veterinarni Medicina 56, 2011, 226-230


NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease
Glubb DM, Gearry RB, Barclay ML, Roberts RL, Pearson J, Keenan JI, McKenzie J, Bentley RW
World Journal of Gastroenterology 17, 2011, 2829-2837


IFN-gamma Inhibits Gastric Carcinogenesis by Inducing Epithelial Cell Autophagy and T-Cell Apoptosis
Tu SP, Quante M, Bhagat G, Takaishi S, Cui GL, Yang XD, Muthuplani S, Shibata W, Fox JG , Pritchard DM, Wang TC
Cancer Research 71, 15-6-2011, 4247-4259


Adalimumab for the Treatment of Immune-Mediated Diseases: An Update on Old and Recent Indications
Murdaca G, Colombo BM, Puppo F
Drugs of Today 47, 2011, 277-288


Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing Non-integrin (DC-SIGN) Recognizes a Novel Ligand, Mac-2-binding Protein, Characteristically Expressed on Human Colorectal Carcinomas
Nonaka M, Ma BY, Imaeda H, Kawabe K, Kawasaki N, Hodohara K, Kawasaki N, Andoh A, Fujiyama Y, Kawasaki T
Journal of Biological Chemistry 286, 24-6-2011, 22403-22413


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Rosenfeld GA, Bressler B
Canadian Journal of Gastroenterology 25, 2011, 298


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Kuenstner JT
Canadian Journal of Gastroenterology 25, 2011, 297-298


Defective innate immunity in inflammatory bowel disease: a Crohn's disease exclusivity?
Marks DJB
Current Opinion in Gastroenterology 27, 2011, 328-334


Leprosy susceptibility: genetic variations regulate innate and adaptive immunity, and disease outcome
Cardoso CC, Pereira AC, Marques CD, Moraes MO
Future Microbiology 6, 2011, 533-549


Characterization of the Mycobacterium avium subsp paratuberculosis laminin-binding/histone-like protein (Lbp/Hlp) which reacts with sera from patients with Crohn's disease
Lefrancois LH, Pujol C, Bodier CC, Teixeira-Gomez AP, Drobecq H, Rosso ML, Raze D, Dias AA, Hugot JP, Chacon O, Barletta RG, Locht C, Pessolani MCV, Biet F
Microbes and Infection 13, 2011, 585-594


Interferon-gamma release assays for diagnosis of latent tuberculosis infection: evidence in immune-mediated inflammatory disorders
Smith R, Cattamanchi A, Steingart KR, Denkinger C, Dheda K, Winthrop KL, Pai M
Current Opinion in Rheumatology 23, 2011, 377-384


Experimental infection of a bovine model with human isolates of Mycobacterium avium subsp paratuberculosis
Allen AJ, Park KT, Barrington GM, Lahmers KK, Abdellrazeq GS, Rihan HM, Sreevatsan S, Davies C, Hamilton MJ, Davis WC
Veterinary Immunology and Immunopathology 141, 2011, 258-266


Synthesis of biotinylated muramyl tripeptides with NOD2-stimulating activity
Gisch N, Buske B, Heine H, Lindner B, Zahringer U
Bioorganic & Medicinal Chemistry Letters 21, 2011, 3362-3366


Polymerase chain reaction-restriction fragment length polymorphism of the rpoB gene for identification of Mycobacterium avium subsp paratuberculosis and differentiation of Mycobacterium avium subspecies
Whang J, Lee BS , Choi GE, Cho SN, Kil PY, Collins MT, Shin SJ
Diagnostic Microbiology and Infectious Disease 70, 2011, 65-71


Serum Antibodies to Mycobacterium avium Subspecies paratuberculosis Combined with Anti-Saccharomyces cerevisiae Antibodies in Crohn's Disease Patients: Prevalence and Diagnostic Role
Biet F, Gendt L , Anton E, Ballot E, Hugot JP, Johanet C
Digestive Diseases and Sciences 56, 2011, 1794-1800


Peculiar antibody reactivity to human connexin 37 and its microbial mimics in patients with Crohn's disease
Koutsoumpas A, Polymeros D, Tsiamoulos Z, Smyk D, Karamanolis G, Triantafyllou K, Rigopoulou EI, Forbes A, Vergani D, Bogdanos DP, Ladas SD
Journal of Crohns & Colitis 5, 2011, 101-109


Vitamin D and Inflammatory Bowel Disease
Ardizzone S, Cassinotti A, Bevilacqua M, Clerici M, Porro GB
Vitamins and the Immune System 86, 2011, 367-377


Emerging Pathogenic Bacteria: Mycobacterium avium subsp paratuberculosis in Foods
Kim JH, Griffiths MW
Korean Journal for Food Science of Animal Resources 31, 2011, 147-157


Antibacterial effects of vitamin D
Hewison M
Nature Reviews Endocrinology 7, 2011, 336-344


NLRP3 Inflammasome Plays a Key Role in the Regulation of Intestinal Homeostasis
Hirota SA, Ng J , Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, MacDonald JA, Beck PL
Inflammatory Bowel Diseases 17, 2011, 1359-1372


Increased frequencies of T helper type 17 cells in tuberculous pleural effusion
Wang TT, Lv MM, Qian Q, Nie YZ, Yu LK, Hou YY
Tuberculosis 91, 2011, 231-237


Caspase-1-Processed Cytokines IL-1 beta and IL-18 Promote IL-17 Production by gamma delta and CD4 T Cells That Mediate Autoimmunity
Lalor SJ, Dungan LS, Sutton CE, Basdeo SA, Fletcher JM, Mills KHG
Journal of Immunology 186, 2011, 5738-5748


Characterization of Changes in Serum Anti-Glycan Antibodies in Crohn's Disease - a Longitudinal Analysis
Rieder F, Lopez R, Franke A, Wolf A, Schleder S, Dirmeier A, Schirbel A, Rosenstiel P, Dotan N, Schreiber S, Rogler G, Klebl F
Plos One 6, 2011, Article Number: e18172


Gender and the hygiene hypothesis
Clough S
Social Science & Medicine 72, 2011, 486-493


Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands
Magalhaes JG, Lee J, Geddes K, Rubino S, Philpott DJ, Girardin SE
European Journal of Immunology 41, 2011, 1445-1455


Persistent enteric mycobacterial infection enhances sensitivity to acute mucosal injury
Johnson CS, Wannemuehler MJ, Hostetter JM
Experimental Biology and Medicine 236, 2011, 36-43


Highly Specific and Quick Detection of Mycobacterium avium subsp paratuberculosis in Feces and Gut Tissue of Cattle and Humans by Multiple Real-Time PCR Assays
Imirzalioglu C, Dahmen H, Hain T, Billion A, Kuenne C, Chakraborty T, Domann E
Journal of Clinical Microbiology 49, 2011, 1843-1852


Presence of intestinal Mycobacterium avium subspecies paratuberculosis (MAP) DNA is not associated with altered MMP expression in ulcerative colitis
Rath T, Roderfeld M, Blocher S, Rhode A, Basler T, Akineden O, Abdulmawjood A, Halwe JM, Goethe R, Bulte M, Roeb E
Bmc Gastroenterology 11, 2011, Article Number: 34


Dual roles of NOD2 in TLR4-mediated signal transduction and -induced inflammatory gene expression in macrophages
Tsai WH, Huang DY, Yu YH, Chen CY, Lin WW
Cellular Microbiology 13, 2011, 717-730


Celastrus-derived Celastrol Suppresses Autoimmune Arthritis by Modulating Antigen-induced Cellular and Humoral Effector Responses
Venkatesha SH, Yu H, Rajaiah R, Tong L, Moudgil KD
Journal of Biological Chemistry 286, 2011, 15138-15146


Nicotine-Induced Differential Modulation of Autoimmune Arthritis in the Lewis Rat Involves Changes in Interleukin-17 and Anti-Cyclic Citrullinated Peptide Antibodies
Yu H, Yang YH, Rajaiah R, Moudgil KD
Arthritis and Rheumatism 63, 2011, 981-991


Current perspectives on Mycobacterium avium subsp paratuberculosis, Johne's disease, and Crohn's disease: a Review
Over K, Crandall PG, O'Bryan CA, Ricke SC
Critical Reviews in Microbiology 37, 2011, 141-156


Detection of Mycobacterium avium subsp paratuberculosis (MAP)-specific IS900 DNA and Antibodies Against MAP Peptides and Lysate in the Blood of Crohn's Disease Patients
Di Sabatino A, Paccagnini D, Vidali F, Rosu V, Biancheri P, Cossu A, Zanetti S, Corazza GR, Sechi LA
Inflammatory Bowel Diseases 17, 2011, 1254-1255


Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes
Duerr CU, Salzman NH, Dupont A, Szabo A, Normark BH, Normark S, Locksley RM, Mellroth P, Hornef MW
Mucosal Immunology 4, 2011, 325-334


Association of Mycobacterium avium subsp paratuberculosis with Multiple Sclerosis in Sardinian Patients
Cossu D, Cocco E, Paccagnini D, Masala S, Ahmed N, Frau J, Marrosu MG, Sechi LA
Plos One 6, 2011, Article Number: e18482 Published: APR 13 2011


Antibodies to Myelin P0 and Ceramide Perpetuate Neuropathy in Long Standing Treated Leprosy Patients
Raju R, Devi SK , Mehervani C, Kumar AS, Meena AK, Reddy PP, Pranay P, Jain S, rchelos-Gracia JJ, Suneetha S, Suneetha LM
Neurochemical Research 36, 2011, 766-773


Crohn disease A current perspective on genetics, autophagy and immunity
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Autophagy 7, 2011, 355-374


Genome-wide association studies and susceptibility to infectious diseases
Newport MJ, Finan C
Briefings in Functional Genomics 10, 2011, 98-107


A comparison of an interferon-gamma release assay and tuberculin skin test in refractory inflammatory disease patients screened for latent tuberculosis prior to the initiation of a first tumor necrosis factor alpha inhibitor
Kwakernaak AJ, Houtman PM, Weel JFL, Spoorenberg JPL, Jansen TLTA
Clinical Rheumatology 30, 2011, 505-510


Association of CARD8 with inflammatory bowel disease in Koreans
Yang SK, Kim H, Hong M, Lim J, Choi E, Ye BD, Park SK, Song K
Journal of Human Genetics 56, 2011, 217-223


Genome-Wide Expression Profiling Identifies an Impairment of Negative Feedback Signals in the Crohn's Disease-Associated NOD2 Variant L1007fsinsC
Billmann-Born S, Till A, Arlt A, Lipinski S, Sina C, Latiano A, Annese V, Hasler R, Kerick M, Manke T, Seegert D, Hanidu A, Schafer H, van Heel D, Li J, Schreiber S, Rosenstiel P
Journal of Immunology 186, 2011, 4027-4038


Can an Immunohistochemistry Method Differentiate Intestinal Tuberculosis from Crohn's Disease in Biopsy Specimens?
Ince AT, Gunes P, Senates E, Sezikli M, Tiftikci A, Ovunc O
Digestive Diseases and Sciences 56, 2011, 1165-1170


Whole-Genome association analysis of susceptibility to paratuberculosis in Holstein cattle
Kirkpatrick BW, Shi X, Shook GE, Collins MT
Animal Genetics 42, 2011, 149-160


Mycobacterium avium subsp paratuberculosis in Dairy Products, Meat, and Drinking Water
Gill CO, Saucier L, Meadus WJ
Journal of Food Protection 74, 2011, 480-499


The role of bacteria and pattern-recognition receptors in Crohn's disease
Man SM, Kaakoush NO, Mitchell HM
Nature Reviews Gastroenterology & Hepatology 8, 2011, 152-168


Infection, immunoregulation, and cancer
Rook GAW, Dalgleish A
Immunological Reviews 240, 2011, 141-159


Human genetic susceptibility to intracellular pathogens
Vannberg FO, Chapman SJ, Hill AVS
Immunological Reviews 240, 2011, 105-116


Interferon-inducible protein-10 as a marker to detect latent and active tuberculosis in rheumatoid arthritis
Chen DY, Shen GH, Chen YM, Chen HH, Lin CC, Hsieh CW, Lan JL
International Journal of Tuberculosis and Lung Disease 15, 2011, 192-199


Nod2 Suppresses Borrelia burgdorferi Mediated Murine Lyme Arthritis and Carditis through the Induction of Tolerance
Petnicki-Ocwieja T, DeFrancesco AS, Chung E, Darcy CT, Bronson RT, Kobayashi KS, Hu LT
Plos One 6, 2011,


gamma delta T cell Receptor Ligands and Modes of Antigen Recognition
Champagne E
Archivum Immunologiae et Therapiae Experimentalis 59, 2011, 117-137


Growth of M. avium Subspecies Paratuberculosis in Culture Is Enhanced by Nicotinic Acid, Nicotinamide, and alpha and beta Nicotinamide Adenine Dinucleotide
Greenstein RJ, Su LY, Brown ST
Digestive Diseases and Sciences 56, 2011, 368-375


TLR2 deficiency by compromising p19 (IL-23) expression limits T-h 17 cell responses to Mycobacterium tuberculosis
Teixeira-Coelho M, Cruz A, Carmona J, Sousa C, Ramos-Pereira D, Saraiva AL, Veldhoen M, Pedrosa J, Castro AG, Saraiva M
International Immunology 23, 2011, 89-96


A Novel Motif in the Crohn's Disease Susceptibility Protein, NOD2, Allows TRAF4 to Down-regulate Innate Immune Responses
Marinis JM, Homer CR, McDonald C, Abbott DW
Journal of Biological Chemistry 286, 2011, 1938-1950


Hsp70 vaccination-induced antibodies recognize B cell epitopes in the cell wall of Mycobacterium avium subspecies paratuberculosis
Santema W, van Kooten P, Hoek A, Leeflang M, Overdijk M, Rutten V, Koets A
Vaccine 29, 2011, 1364-1373


NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M-bovis BCG in human macrophages
Brooks MN, Rajaram MVS, Azad AK, Amer AO, Valdivia-Arenas MA, Park JH, Nunez G, Schlesinger LS
Cellular Microbiology 13, 2011, 402-418


Interleukin-27 and Interferon-gamma Are Involved in Regulation of Autoimmune Arthritis
Rajaiah R, Puttabyatappa M, Polumuri SK, Moudgil KD
Journal of Biological Chemistry 286, 2011, 2817-2825


Differentiation of Crohn's disease from intestinal tuberculosis in India in 2010
Pulimood AB, Amarapurkar DN, Ghoshal U, Phillip M , Pai CG, Reddy DN, Nagi B, Ramakrishna BS
World Journal of Gastroenterology 17, 2011, 433-443


Multiplex suspension array for human anti-carbohydrate antibody profiling
Pochechueva T, Chinarev A, Spengler M, Korchagina E, Heinzelmann-Schwarz V, Bovin N, Rieben R
Analyst 136, 2011, 560-569


Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins
Sioud M, Mobergslien A, Boudabous A, Floisand Y
International Journal of Oncology 38, 2011, 385-390


Detection of Mycobacterium avium ssp paratuberculosis in cheese, milk powder and milk using IS900 and f57-based qPCR assays
Donaghy JA, Johnston J, Rowe MT
Journal of Applied Microbiology 110, 2011, 479-489


Association of Mycobacterium avium subspecies paratuberculosis With Crohn Disease in Pediatric Patients
Lee A, Griffiths TA, Parab RS, King RK, Dubinsky MC, Urbanski SJ, Wrobel I, Rioux KP
Journal of Pediatric Gastroenterology and Nutrition 52, 2011, 170-174


Leprosy as a genetic disease
Alter A, Grant A, Abel L, Alcais A, Schurr E
Mammalian Genome 22, 2011, 19-31


Immunogenicity of Mycobacterium avium subsp. paratuberculosis proteins in Crohn's disease patients
Bach H, Ko HH, Raizman EA, Attarian R, Cho BA, Biet F, Enns R, Bressler B
Scandinavian Journal of Gastroenterology 46, 2011, 30-39


Autophagy in immunity and inflammation
Levine B, Mizushima N, Virgin HW
Nature 469, 2011, 323-335


DNA vaccines: an historical perspective and view to the future
Liu MA
Immunological Reviews 239, 2011, 62-84


MECHANISMS OF DISEASE Immunodeficiency and Genetic Defects of Pattern-Recognition Receptors
Netea MG, van der Meer JWM
New England Journal of Medicine 364, 2011, 60-70


PTPN22 gene polymorphisms in autoimmune diseases with special reference to systemic lupus erythematosus disease susceptibility
Pradhan V, Borse V, Ghosh K
Journal of Postgraduate Medicine 56, 2010, 239-U85


Repetitive Pertussis Toxin Promotes Development of Regulatory T Cells and Prevents Central Nervous System Autoimmune Disease
Weber MS, Benkhoucha M, Lehmann-Horn K, Hertzenberg D, Sellner J, Santiago-Raber ML, Chofflon M, Hemmer B, Zamvil SS, Lalive PH
Plos One 5, 2010, Article Number: e16009 Published: DEC 30 2010


C-type lectins, fungi and Th17 responses
Vautier S, Sousa MD, Brown GD
Cytokine & Growth Factor Reviews 21, 2010, 405-412


Tim3 binding to galectin-9 stimulates antimicrobial immunity
Jayaraman P, Sada-Ovalle I, Beladi S, Anderson AC , Dardalhon V, Hotta C, Kuchroo VK, Behar SM
Journal of Experimental Medicine 207, 2010, 2343-2354


Bacterial Induction of Proinflammatory Cytokines in Inflammatory Bowel Disease
Klapproth JMA, Sasaki M
Inflammatory Bowel Diseases 16, 2010, 2173-2179


Human IRGM gene to be or not to be
Bekpen C, Xavier RJ, Eichler EE
Seminars in Immunopathology 32, 2010, 437-444


Autoimmunity as a Predisposition for Infectious Diseases
Maddur MS, Vani J, Lacroix-Desmazes S, Kaveri S, Bayry J
Plos Pathogens 6, 2010, Article Number: e1001077 Published: NOV 2010


Complications of Tumor Necrosis Factor-alpha Blockade in Chronic Granulomatous Disease-Related Colitis
Uzel G, Orange JS, Poliak N, Marciano BE, Heller T, Holland SM
Clinical Infectious Diseases 51, 2010, 1429-1434


Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses
Tigno-Aranjuez JT, Asara JM, Abbott DW
Genes & Development 24, 2010, 2666-2677


Golimumab and certolizumab: The two new anti-tumor necrosis factor kids on the block
Mittal M, Raychaudhuri SP
Indian Journal of Dermatology Venereology & Leprology 76, 2010, 602-609


Paucity of mycobacteria in mucosal bowel biopsies from adults and children with early inflammatory bowel disease
Ricanek P, Lothe SM, Szpinda I, Jorde AT, Brackmann S, Perminow G, Jorgensen KK, Rydning A, Vatn MH, Tonjum T
Journal of Crohns & Colitis 4, 2010, 561-566


Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria
Singh SB, Ornatowski W, Vergne I, Naylor J, Delgado M, Roberts E, Ponpuak M, Master S, Pilli M, White E, Komatsu M, Deretic V
Nature Cell Biology 12, 2010, 1154-1165


Genetic association between bovine NOD2 polymorphisms and infection by Mycobacterium avium subsp paratuberculosis in Holstein-Friesian cattle
Ruiz-Larranaga O, Garrido JM, Iriondo M, Manzano C, Molina E, Koets AP, Rutten VPMG, Juste RA, Estonba A
Animal Genetics 41, 2010, 652-655


Infectious Causes of Appendicitis
Lamps LW
Infectious Disease Clinics of North America 24, 2010, 995-+


Influences of Intestinal Bacteria in Human Inflammatory Bowel Disease
Vanderploeg R, Panaccione R, Ghosh S, Rioux K
Infectious Disease Clinics of North America 24, 2010, 977-+


CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunity
Vaitaitis GM, Wagner DH
Molecular Immunology 47, 2010, 2303-2313


The protein Nod2: An innate receptor more complex than previously assumed
Lecat A, Piette J, Legrand-Poels S
Biochemical Pharmacology 80, 2010, 2021-2031


Th1-driven immune reconstitution disease in Mycobacterium avium-infected mice
Barber DL, Mayer-Barber KD, Antonelli LRV, Wilson MS, White S, Caspar P, Hieny S, Sereti I, Sher A
Blood 116, 2010, 3485-3493


Function of NOD-like receptors in immunity and disease
Dagenais M, Dupaul-Chicoine J, Saleh M
Current Opinion in Investigational Drugs 11, 2010, 1246-1255


Nod1 and Nod2 Regulation of Inflammation in the Salmonella Colitis Model
Geddes K, Rubino S, Streutker C, Cho JH, Magalhaes JG, Le Bourhis L, Selvanantham T, Girardin SE, Philpott DJ
Infection and Immunity 78, 2010, 5107-5115


Eating the enemy in Crohn's disease An old theory revisited
Caprilli R, Lapaquette P, rfeuille-Michaud A
Journal of Crohns & Colitis 4, 2010, 377-383


Chronic yersiniosis due to defects in the TLR5 and NOD2 recognition pathways
Netea MG, van der Leij F, Drenth JPH, Joosten LAB , Morsche RT, Verweij P, de Jong D, Kullberg BJ, van der Meer JWM
Netherlands Journal of Medicine 68, 2010, 310-315


Inhibitory effects of alprazolam on the development of acute experimental autoimmune encephalomyelitis in stressed rats
Nunez-Iglesias MJ, Novio S, meida-Dias A, Freire-Garabal M
Pharmacology Biochemistry and Behavior 97, 2010, 350-356


Research on Mycobacterium avium during the period 1995 to 2009
Kaevska M, Hruska K
Veterinarni Medicina 55, 2010, 473-482


Crohn's Disease Susceptibility Gene Interactions, a NOD to the Newcomer ATG16L1
Cadwell K
Gastroenterology 139, 2010, 1448-1450


Mycobacterium avium paratuberculosis and the etiology of Crohn's disease: A review of the controversy from the clinician's perspective
Rosenfeld G, Bressler B
Canadian Journal of Gastroenterology 24, 2010, 619-624


Immunodeficiency secondary to anticytokine autoantibodies
Browne SK, Holland SM
Current Opinion in Allergy and Clinical Immunology 10, 2010, 534-541


ATG16L1 and NOD2 Interact in an Autophagy-Dependent Antibacterial Pathway Implicated in Crohn's Disease Pathogenesis
Homer CR, Richmond AL, Rebert NA, Achkar JP, McDonald C
Gastroenterology 139, 2010, 1630-+


The innate immune system in the intestine
Uematsu S, Fujimoto K
Microbiology and Immunology 54 , 2010, 645-657


Detection of Mycobacterium avium subsp. paratuberculosis in Drinking Water and Biofilms by Quantitative PCR
Beumer A, King D, Donohue M, Mistry J, Covert T, Pfaller S
Applied and Environmental Microbiology 76, 2010, 7367-7370


Solid-phase synthesis of a pentavalent GalNAc-containing glycopeptide (Tn antigen) representing the nephropathy-associated IgA hinge region
Bolscher JGM, Brevoord J, Nazmi K, Ju TZ, Veerman ECI, van Wijk JAE, Cummings RD, van Die I
Carbohydrate Research 345, 2010, 1998-2003


The Involvement of Heat-Shock Proteins in the Pathogenesis of Autoimmune Arthritis: A Critical Appraisal
Huang MN, Yu H, Moudgil KD
Seminars in Arthritis and Rheumatism 40, 2010, 164-175


The Role of Bacteria in the Pathogenesis of Inflammatory Bowel Disease
Friswell M, Campbell B, Rhodes J
Gut and Liver 4, 2010, 295-306


Protein interaction network and signaling pathways activated by muramyl peptides
Meshcheryakova EA, Andronova TM, Ivanov VT
Russian Journal of Bioorganic Chemistry 36, 2010, 535-549


Pre-illness changes in dietary habits and diet as a risk factor for inflammatory bowel disease: A case-control study
Maconi G, Ardizzone S, Cucino C, Bezzio C, Russo AG, Porro GB
World Journal of Gastroenterology 16, 2010, 4297-4304


Differential induction of inflammatory cytokines by dendritic cells treated with novel TLR-agonist and cytokine based cocktails: targeting dendritic cells in autoimmunity
Jensen SS, Gad M
Journal of Inflammation-London 7, 2010,


Molecular Characterisation of Indian Strains of Mycobacterium avium subspecies paratuberculosis by Pulsed-Field Gel Electrophoresis
Tripathi BN, Stevenson K
Journal of Applied Animal Research 37, 2010, 247-251


Invited review: Modeling within-herd transmission of Mycobacterium avium subspecies paratuberculosis in dairy cattle: A review
Marce C, Ezanno P, Weber MF, Seegers H, Pfeiffer DU, Fourichon C
Journal of Dairy Science 93, 2010, 4455-4470


High prevalence of viable Mycobacterium avium subspecies paratuberculosis in Crohn's disease
Mendoza JL, San-Pedro A, Culebras E, Cies R, Taxonera C, Lana R, Urcelay E, de la Torre F, Picazo JJ, az-Rubio M
World Journal of Gastroenterology 16, 2010, 4558-4563


Association of NOD1 (CARD4) insertion/deletion polymorphism with susceptibility to IBD: A meta-analysis
Lu WG, Zou YF, Feng XL, Yuan FL, Gu YL, Li X, Li CW, Jin C, Li JP
World Journal of Gastroenterology 16, 2010, 4348-4356


Synthesis of biologically active biotinylated muramyl dipeptides
Grimes CL, Podolsky DK, O'Shea EK
Bioorganic & Medicinal Chemistry Letters 20, 2010, 6061-6063


Expression of NRAMP1 and iNOS in Mycobacterium avium subsp. paratuberculosis naturally infected cattle
Delgado F, Estrada-Chavez C, Romano M, Paolicchi F, Blanco-Viera F, Capellino F , Chavez-Gris G, Pereira-Suarez AL
Comparative Immunology Microbiology and Infectious Diseases 33, 2010, 389-400


Atypical mycobacteria: showerheads, anti-TNF therapy and Crohn's disease
Desai AA, Marks DJB
Expert Review of Clinical Immunology 6, 2010, 695-699


IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes
Seite JF, Cornec D, Renaudineau Y, Youinou P, Mageed RA, Hillion S
Blood 116, 2010, 1698-1704


Intracellular pH of Mycobacterium avium subsp paratuberculosis following exposure to antimicrobial compounds monitored at the single cell level
Gaggia F, Nielsen DS, Biavati B, Siegumfeldt H
International Journal of Food Microbiology 141, Suppl. 1, 2010, S188-S192


Rapid detection methods for viable Mycobacterium avium subspecies paratuberculosis in milk and cheese
Botsaris G, Slana I, Liapi M, Dodd C, Economides C, Rees C, Pavlik I
International Journal of Food Microbiology 141 , Suppl. 1, 2010, S87-S90


Mycobacterium avium subsp paratuberculosis viability determination using F57 quantitative PCR in combination with propidium monoazide treatment
Kralik P, Nocker A, Pavlik I
International Journal of Food Microbiology 141, Suppl. 1, 2010, S80-S86


Epitopes of Mycobacterium avium ssp paratuberculosis 70 kDa heat-shock protein activate bovine helper T cells in outbred cattle
Hoek A, Rutten VPMG, van der Zee R, Davies CJ, Koets AP
Vaccine 28, 2010, 5910-5919


Pulmonary Infectious Complications of Tumor Necrosis Factor Blockade
Wallis RS, Schluger NW
Infectious Disease Clinics of North America 24, 2010, 681-+


Gut bacterium of Dendrobaena veneta (Annelida: Oligochaeta) possesses antimycobacterial activity
Fiolka MJ, Zagaja MP, Piersiak TD, Wrobel M, Pawelec J
Journal of Invertebrate Pathology 105, 2010, 63-73


Abnormalities in the Handling of Intracellular Bacteria in Crohn's Disease
Lapaquette P, rfeuille-Michaud A
Journal of Clinical Gastroenterology 44, 2010, S26-S29


A novel immunoregulatory function for IL-23: Inhibition of IL-12-dependent IFN-gamma production
Sieve AN, Meeks KD, Lee S, Berg RE
European Journal of Immunology 40, 2010, 2236-2247


Peptidoglycan Recognition Proteins Protect Mice from Experimental Colitis by Promoting Normal Gut Flora and Preventing Induction of Interferon-gamma
Saha S, Jing XF , Park SY, Wang SY, Li XN, Gupta D, Dziarski R
Cell Host & Microbe 8, 2010, 147-162


Vitamin D and host resistance to infection? Putting the cart in front of the horse
Bruce D, Ooi JH , Yu SH, Cantorna MT
Experimental Biology and Medicine 235, 2010, 921-927


Serum Anti-Glycan Antibodies Predict Complicated Crohn's Disease Behavior: A Cohort Study
Rieder F, Schleder S, Wolf A, Dirmeier A, Strauch U, Obermeier F, Lopez R, Spector L, Fire E, Yarden J, Rogler G, Dotan N, Klebl F
Inflammatory Bowel Diseases 16, 2010, 1367-1375


Association of the NOD2 Genotype with Bacterial Translocation via Altered Cell-cell Contacts in Crohn's Disease Patients
Kosovac K, Brenmoehl J, Holler E, Falk W, Schoelmerich J, Hausmann M, Rogler G
Inflammatory Bowel Diseases 16, 2010, 1311-1321


Crohn's disease as an immunodeficiency
Hayee B, Rahman FZ, Sewell G, Smith AM, Segal AW
Expert Review of Clinical Immunology 6, 2010, 585-596


Mycobacteria in Crohn's disease: how innate immune deficiency may result in chronic inflammation
Lalande JD, Behr MA
Expert Review of Clinical Immunology 6, 2010, 633-641


Vitamin D, NOD2, autophagy and Crohn's disease
Verway M, Behr MA, White JH
Expert Review of Clinical Immunology 6, 2010, 505-508


A Novel Heat-Shock Protein Coinducer Boosts Stress Protein Hsp70 to Activate T Cell Regulation of Inflammation in Autoimmune Arthritis
Wieten L, van der Zee R, Spiering R, Wagenaar-Hilbers J, van Kooten P, Broere F, Van Eden W
Arthritis and Rheumatism 62, 2010, 1026-1035


Identification of Drosophila Yin and PEPT2 as Evolutionarily Conserved Phagosome-associated Muramyl Dipeptide Transporters
Charriere GM, Ip WKE, Dejardin S, Boyer L, Sokolovska A, Cappillino MP, Cherayil BJ, Podolsky DK, Kobayashi KS, Silverman N, Lacy-Hulbert A, Stuart LM
Journal of Biological Chemistry 285, 2010, 20147-20154


Caspase Recruitment Domain-containing Protein 8 (CARD8) Negatively Regulates NOD2-mediated Signaling
von Kampen O, Lipinski S, Till A, Martin SJ, Nietfeld W, Lehrach H, Schreiber S, Rosenstiel P
Journal of Biological Chemistry 285, 2010, 19921-19926


NOD2/CARD15: geographic differences in the Spanish population and clinical applications in Crohn's disease
de Acosta MB, Mendoza JL, Lana R, Munoz JED, Diaz-Rubio M
Revista Espanola de Enfermedades Digestivas 102, 2010, 321-326


Comparison of the Moonlighting Actions of the Two Highly Homologous Chaperonin 60 Proteins of Mycobacterium tuberculosis
Cehovin A, Coates ARM, Hu YM, Riffo-Vasquez Y, Tormay P, Botanch C, Altare F, Henderson B
Infection and Immunity 78, 2010, 3196-3206


Immunization with pVAXhsp65 Decreases Inflammation and Modulates Immune Response in Experimental Encephalomyelitis
Zorzella-Pezavento SFG, Chiuso-Minicucci F, Franca TGD, Ishikawa LLW, Martins DR, Silva CL, Sartori A
Neuroimmunomodulation 17, 2010, 287-297


Analysis of the association between BTNL2 polymorphism and tuberculosis in Chinese Han population
Lian YY, Yue J, Han M, Liu JF, Liu LR
Infection Genetics and Evolution 10, 2010, 517-521


The Pathogen Recognition Receptor NOD2 Regulates Human FOXP3(+) T Cell Survival
Rahman MK, Midtling EH, Svingen PA, Xiong YN, Bell MP, Tung J, Smyrk T, Egan LJ, Faubion WA
Journal of Immunology 184, 2010, 7247-7256


The Thioamides Methimazole and Thiourea Inhibit Growth of M. avium Subspecies paratuberculosis in Culture
Greenstein RJ, Su LY, Brown ST
Plos One 5, 2010, Article Number: e11099 Published: JUN 14 2010


Polymorphisms in the gene encoding bovine interleukin-10 receptor alpha are associated with Mycobacterium avium ssp. paratuberculosis infection status
Verschoor CP, Pant SD, You QM, Schenkel FS, Kelton DF, Karrow NA
Bmc Genetics 11, 2010, Article No. 23-Published: APR 15 2010


A large-scale study of differential gene expression in monocyte-derived macrophages infected with several strains of Mycobacterium avium subspecies paratuberculosis
Kabara E, Kloss CC, Wilson M, Tempelman RJ, Sreevatsan S, Janagama H, Coussens PM
Briefings in Functional Genomics 9, 2010, 220-237


How tumour necrosis factor blockers interfere with tuberculosis immunity
Harris J, Keane J
Clinical and Experimental Immunology 161, 2010, 1-9


Histopathology and TB-PCR kit analysis in differentiating the diagnosis of intestinal tuberculosis and Crohn's disease
Jin XJ, Kim JM, Kim HK, Kim L, Choi SJ, Park IS, Han JY, Chu YC, Song JY, Kwon KS, Kim EJ
World Journal of Gastroenterology 16, 2010, 2496-2503


The Role of TLR2, TRL3, TRL4, and TRL9 Signaling in the Pathogenesis of Autoimmune Disease in a Retinal Autoimmunity Model
Fang JZ, Fang D , Silver PB, Wen F, Li B, Ren XR, Lin Q, Caspi RR, Su SB
Investigative Ophthalmology & Visual Science 51, 2010, 3092-3099


The clinical spectrum and immunobiology of parainfectious neuromyelitis optica (Devic) syndromes
Sellner J, Hemmer B, Muhlau M
Journal of Autoimmunity 34, 2010, 371-379


Lack of association between the occurrence of Crohn's disease and occupational exposure to dairy and beef cattle herds infected with Mycobacterium avium subspecies paratuberculosis
Qual DA, Kaneene JB, Varty TJ, Miller R, Thoen CO
Journal of Dairy Science 93, 2010, 2371-2376


Mycobacterium marinum infection complicated by anti-tumour necrosis factor therapy
Ramos JM, Garcia-Sepulcre MF, Rodriguez JC, Padilla S, Gutierrez F
Journal of Medical Microbiology 59, 2010, 617-621


iTRAQ-based proteomic identification of leucine-rich alpha-2 glycoprotein as a novel inflammatory biomarker in autoimmune diseases
Serada S, Fujimoto M, Ogata A, Terabe F, Hirano T, Iijima H, Shinzaki S, Nishikawa T, Ohkawara T, Iwahori K, Ohguro N, Kishimoto T, Naka T
Annals of the Rheumatic Diseases 69, 2010, 770-774


Mycobacterium tuberculosis heat shock proteins and autoimmunity in sarcoidosis
Dubaniewicz A
Autoimmunity Reviews 9, 2010, 419-424


Recognition of Borrelia burgdorferi by NOD2 Is Central for the Induction of an Inflammatory Reaction
Oosting M, Berende A, Sturm P, ter Hofstede HJM, de Jong DJ, Kanneganti TD, van der Meer JWM, Kullberg BJ, Netea MG, Joosten LAB
Journal of Infectious Diseases 201, 2010, 1849-1858


Non tuberculous anti-TNF associated opportunistic infections
Marie I, Guglielmino E
Revue de Medecine Interne 31, 2010, 353-360


The Path to Crohn's Disease: Is Mucosal Pathology a Secondary Event?
Behr MA
Inflammatory Bowel Diseases 16, 2010, 896-902


MDP-NOD2 Stimulation Induces HNP-1 Secretion, Which Contributes to NOD2 Antibacterial Function
Yamamoto-Furusho JK, Barnich N, Hisamatsu T, Podolsky DK
Inflammatory Bowel Diseases 16, 2010, 736-742


Mycobacteria-Induced Suppression of Autoimmunity in the Central Nervous System
Lee J, Sandor M , Heninger E, Fabry Z
Journal of Neuroimmune Pharmacology 5, 2010, 210-219


Worms to the Rescue: Can Worm Glycans Protect from Autoimmune Diseases?
Kuijk LM, van Die I
Iubmb Life 62, 2010, 303-312


Genetic deficiency of Irgm1 (LRG-47) suppresses induction of experimental autoimmune encephalomyelitis by promoting apoptosis of activated CD4(+) T cells
Xu HW, Wu ZY, Fang F, Guo L, Chen D, Chen JX, Stern D, Taylor GA, Jiang H, Yan SS
Faseb Journal 24, 2010, 1583-1592


Dimeric Le(a) (Le(a)-on-Le(a)) status of beta-haptoglobin in sera of colon cancer, chronic inflammatory disease and normal subjects
Park SY, Yoon SJ, Hakomori SI, Kim JM, Kim JY, Bernert B, Ullman T, Itzkowitz SH, Kim JH
International Journal of Oncology 36, 2010, 1291-1297


Th17 Polarized Cells from Nonobese Diabetic Mice Following Mycobacterial Adjuvant Immunotherapy Delay Type 1 Diabetes
Nikoopour E, Schwartz JA, Huszarik K, Sandrock C, Krougly O, Lee-Chan E, Singh B
Journal of Immunology 184, 2010, 4779-4788


Paradigm redux-Mycobacterium avium subspecies paratuberculosis-macrophage interactions show clear variations between bovine and human physiological body temperatures
Lamont EA, Sreevatsan S
Microbial Pathogenesis 48, 2010, 143-149


Role of interleukin-12 family cytokines in the cellular response to mycobacterial disease
Mendez-Samperio P
International Journal of Infectious Diseases 14, 2010, E366-E371


Redundant and Pathogenic Roles for IL-22 in Mycobacterial, Protozoan, and Helminth Infections
Wilson MS, Feng CG, Barber DL, Yarovinsky F, Cheever AW, Sher A, Grigg M, Collins M, Fouser L, Wynn TA
Journal of Immunology 184, 2010, 4378-4390


Nod proteins link bacterial sensing and autophagy
Travassos LH, Carneiro LAM, Girardin S, Philpott DJ
Autophagy 6, 2010, 409-411


Gene-based vaccines: Recent developments
Liu MA
Current Opinion in Molecular Therapeutics 12, 2010, 86-93


Mycobacterium avium subsp paratuberculosis Detection in Individual and Bulk Tank Milk Samples from Bovine Herds and Caprine Flocks
Favila-Humara LC, Chavez-Gris GG, Carrillo-Casas EM, Hernandez-Castro R
Foodborne Pathogens and Disease 7, 2010, 351-355


Genomewide Association Study of Leprosy
Greenstein RJ, Brown ST
New England Journal of Medicine 362, 2010, 1447


Mycobacterium Tuberculosis, Autoimmunity, and Vitamin D
Shapira Y, gmon-Levin N, Shoenfeld Y
Clinical Reviews in Allergy & Immunology 38, 2010, 169-177


Can Lupus Flares be Associated with Tuberculosis Infection?
Ribeiro FM, Szyper-Kravitz M, Klumb EM, Lannes G, Ribeiro FRE, Albuquerque EMM, Shoenfeld Y
Clinical Reviews in Allergy & Immunology 38, 2010, 163-168


Severe Sporotrichoid Fishtank Granuloma Following Infliximab Therapy for Crohn's Disease
Ben Said B, Kanitakis J, Graber I, Berard F, Nicolas JF, Saurin JC, Augey F
Inflammatory Bowel Diseases 16, 2010, 375-376


Common Polymorphisms in the NOD2 Gene Region Are Associated with Leprosy and Its Reactive States
Berrington WR, Macdonald M, Khadge S, Sapkota BR, Janer M, Hagge DA, Kaplan G, Hawn TR
Journal of Infectious Diseases 201, 2010, 1422-1435


Gene modulation and immunoregulatory roles of Interferon gamma
Saha B, Prasanna SJ, Chandrasekar B, Nandi D
Cytokine 50, 2010, 1-14


Attitudes of Canadian dairy farmers toward a voluntary Johne's disease control program
Sorge U, Kelton D, Lissemore K, Godkin A, Hendrick S, Wells S
Journal of Dairy Science 93, 2010, 1491-1499


CpG-B Oligodeoxynucleotides Inhibit TLR-Dependent and -Independent Induction of Type I IFN in Dendritic Cells
Liu YC, Gray RC , Hardy GAD, Kuchtey J, Abbott DW, Emancipator SN, Harding CV
Journal of Immunology 184, 2010, 3367-3376


Presence, characterization, and genotype profiles of Mycobacterium avium subspecies paratuberculosis from unpasteurized individual and pooled milk, commercial pasteurized milk, and milk products in India by culture, PCR, and PCR-REA methods
Shankar H, Singh SV, Singh PK, Singh AV, Sohal JS, Greenstein RJ
International Journal of Infectious Diseases 14, 2010, E121-E126


Th17 cytokines and vaccine-induced immunity
Lin YY, Slight SR, Khader SA
Seminars in Immunopathology 32, 2010, 79-90


Recognition of commensal microbes: if innate responses are NOD in balance
Rogler G
Expert Review of Clinical Immunology 6, 2010, 205-210


The role of infection in the aetiology of inflammatory bowel disease
Hansen R, Thomson JM, El-Omar EM, Hold GL
Journal of Gastroenterology 45, 2010, 266-276


Analysis of publications on paratuberculosis from 1995 to 2009 with emphasis on the period from 2005 to 2009
Kaevska M, Hruska K
Veterinarni Medicina 55, 2010, 43-54


NOD2-associated diseases: Bridging innate immunity and autoinflammation
Borzutzky A, Fried A, Chou J, Bonilla FA, Kim S, Dedeoglu F
Clinical Immunology 134, 2010, 251-261


Mycobacterium avium subsp Paratuberculosis (MAP) as a Modifying Factor in Crohn's Disease
Sibartie S, Scully P, Keohane J, O'Neill S, O'Mohony J, O'Hanlon D, Kirwan WO, O'Mahony L, Shanahan F
Inflammatory Bowel Diseases 16, 2010, 296-304


Association of the Novel Serologic Anti-glycan Antibodies Anti-laminarin and Anti-chitin with Complicated Crohn's Disease Behavior
Rieder F, Schleder S, Wolf A, Dirmeier A, Strauch U, Obermeier F, Lopez R, Spector L, Fire E, Yarden J, Rogler G, Dotan N, Klebl F
Inflammatory Bowel Diseases 16, 2010, 263-274


Transient role of CD4(+)CD25(+) regulatory T cells in mycobacterial infection in mice
Ozeki Y, Sugawara I, Udagawa T, Aoki T, Osada-Oka M, Tateishi Y, Hisaeda H, Nishiuchi Y, Harada N, Kobayashi K, Matsumoto S
International Immunology 22, 2010, 179-189


Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches
Barreau F, Madre C, Meinzer U, Berrebi D, Dussaillant M, Merlin F, Eckmann L, Karin M, Sterkers G, Bonacorsi S, Lesuffleur T, Hugot JP
Gut 59, 2010, 207-217


Mechanisms of probiotic actions - A review
Oelschlaeger TA
International Journal of Medical Microbiology 300, 2010, 57-62


Th1 and Th17 cells Adversaries and collaborators
Damsker JM, Hansen AM, Caspi RR
Year in Immunology 2 1183, 2010, 211-221


Galectins: regulators of acute and chronic inflammation
Liu FT, Rabinovich GA
2010, 158-182


Long-Term Antibiotic Treatment for Crohn's Disease: Systematic Review and Meta-Analysis of Placebo-Controlled Trials
Feller M, Huwiler K, Schoepfer A, Shang AJ, Furrer H, Egger M
Clinical Infectious Diseases 50, 2010, 473-480


Emerging Bacterial Pathogens in Meat and Poultry: An Overview
Mor-Mur M, Yuste J
Food and Bioprocess Technology 3, 2010, 24-35


Optimisation of culture of Mycobacterium avium subspecies paratuberculosis from blood samples
Bower K, Begg DJ, Whittington RJ
Journal of Microbiological Methods 80, 2010, 93-99


Neonatal BCG Immunization Followed by DNAhsp65 Boosters: Highly Immunogenic but not Protective Against Tuberculosis - a Paradoxical Effect of the Vector?
Pelizon AC, Martins DR, Zorzella-Pezavento SFG, Seger J, Justulin LA, da Fonseca DM, Santos RR, Masson AP, Silva CL, Sartori A
Scandinavian Journal of Immunology 71, 2010, 63-69


Crohn's Disease: an Immune Deficiency State
Marks DJB, Rahman FZ, Sewell GW, Segal AW
Clinical Reviews in Allergy & Immunology 38, 2010, 20-31


Tolerogenic Dendritic Cells in the Control of Autoimmune Neuroinflammation: An Emerging Role of Protein-Glycan Interactions
Ilarregui JM, Rabinovich GA
Neuroimmunomodulation 17 , 2010, 157-160


Identification of seroreactive proteins in the culture filtrate antigen of Mycobacterium avium ssp paratuberculosis human isolates to sera from Crohn's disease patients
Shin AR, Kim HJ , Cho SN, Collins MT, Manning EJB, Naser SA, Shin SJ
Fems Immunology and Medical Microbiology 58, 2010, 128-137


Direct and Indirect Induction by 1,25-Dihydroxyvitamin D-3 of the NOD2/CARD15-Defensin beta 2 Innate Immune Pathway Defective in Crohn Disease
Wang TT, Dabbas B, Laperriere D, Bitton AJ, Soualhine H, Tavera-Mendoza LE, Dionne S, Servant MJ, Bitton A, Seidman EG, Mader S, Behr MA, White JH
Journal of Biological Chemistry 285, 2010, 2237-2241


Molecular identification of Mycobacterium avium subspecies paratuberculosis in an Italian patient with Hashimoto's thyroiditis and Melkersson-Rosenthal syndrome
D'Amore M, Lisi S, Sisto M, Cucci L, Dow CT
Journal of Medical Microbiology 59, 2010, 137-139


Regulation of type 1 diabetes, tuberculosis, and asthma by parasites
Liu ZG, Liu Q, Bleich D, Salgame P, Gause WC
Journal of Molecular Medicine-Jmm 88, 2010, 27-38


How the Noninflammasome NLRs Function in the Innate Immune System
Ting JPY, Duncan JA, Lei Y
Science 327, 2010, 286-290


Strain diversity within Mycobacterium avium subspecies paratuberculosis-A review
Sohal JS, Singh SV, Singh AV, Singh PK
Indian Journal of Experimental Biology 48, 2010, 7-16


NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, Ferguson DJP, Campbell BJ, Jewell D, Simmons A
Nature Medicine 16, 2010, 90-U128


A NOD for autophagy
Netea MG, Joosten LAB
Nature Medicine 16, 2010, 28-30


Reduced transcript stabilization restricts TNF-alpha expression in RAW264.7 macrophages infected with pathogenic mycobacteria: evidence for an involvement of lipomannan
Basler T, Holtmann H, Abel J, Eckstein T, Baumer W, Valentin-Weigand P, Goethe R
Journal of Leukocyte Biology 87, 2010, 173-183


Yeasts: Neglected Pathogens
Poulain D, Sendid B, Standaert-Vitse A, Fradin C , Jouault T, Jawhara S, Colombel JF
Digestive Diseases 27, 2009, 104-110


Bacterial Flora in Inflammatory Bowel Disease
Marteau P
Digestive Diseases 27, 2009, 99-103


Galectin-2 Suppresses Contact Allergy by Inducing Apoptosis in Activated CD8(+) T Cells
Loser K, Sturm A, Voskort M, Kupas V, Balkow S, Auriemma M, Sternemann C, Dignass AU, Luger TA, Beissert S
Journal of Immunology 182, 2009, 5419-5429


Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders
Fukata M, Vamadevan AS, Abreu MT
Seminars in Immunology 21, 2009, 242-253


Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10
Ilarregui JM, Croci DO, Bianco GA, Toscano MA, Salatino M, Vermeulen ME, Geffner JR, Rabinovich GA
Nat.Immunol. 10, 2009, 981-991


Autophagy in Immunity Against Mycobacterium tuberculosis: a Model System to Dissect Immunological Roles of Autophagy
Deretic V, Delgado M, Vergne I, Master S, De Haro S, Ponpuak M, Singh S
Autophagy in Infection and Immunity 335, 2009, 169-188


Linking Chronic Infection and Autoimmune Diseases: Mycobacterium avium Subspecies paratuberculosis, SLC11A1 Polymorphisms and Type-1 Diabetes Mellitus
Paccagnini D, Sieswerda L, Rosu V, Masala S, Pacifico A, Gazouli M, Ikonomopoulos J, Ahmed N, Zanetti S, Sechi LA
Plos One 4, 2009, Issue 9, Article Number e7109


Isolation of Mycobacterium avium Subspecies paratuberculosis Reactive CD4 T Cells from Intestinal Biopsies of Crohn's Disease Patients
Olsen I, Tollefsen S, Aagaard C, Reitan LJ, Bannantine JP, Andersen P, Sollid LM, Lundin KEA
Plos One 4, 2009, Issue 5, Article Number e5641


Specific Immunoassays Confirm Association of Mycobacterium avium Subsp paratuberculosis with Type-1 but Not Type-2 Diabetes Mellitus
Rosu V, Ahmed N , Paccagnini D, Gerlach G, Fadda G, Hasnain SE, Zanetti S, Sechi LA
Plos One 4, 2009, Issue 2, Article Number e4386


Administration of Mycobacterium leprae rHsp65 Aggravates Experimental Autoimmune Uveitis in Mice
Marengo EB, Commodaro AG, Peron JPS, de Moraes LV , Portaro FCV, Belfort R, Rizzo LV, Sant'Anna OA
Plos One 4, 2009, Issue 11, Article Number e7912


Evidence for Impaired CARD15 Signalling in Crohn's Disease without Disease Linked Variants
Seidelin JB, Broom OJ, Olsen J, Nielsen OH
Plos One 4, 2009, Issue 11, Article Number e7794


A Common Genetic Fingerprint in Leprosy and Crohn's Disease?
Schurr E, Gros P
New England Journal of Medicine 361, 2009, 2666-2668


The TNF superfamily in 2009: new pathways, new indications, and new drugs
Tansey MG, Szymkowski DE
Drug Discovery Today 14, 2009, 1082-1088


Alternatively activated macrophages in infection and autoimmunity
Fairweather D, Cihakova D
Journal of Autoimmunity 33, 2009, 222-230


Self heat-shock protein 65-mediated regulation of autoimmune arthritis
Durai M, Huang MN, Moudgil KD
Journal of Autoimmunity 33, 2009, 208-213


Nucleotide oligomerization domain-2 interacts with 2 '-5 '-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells
Dugan JW, Albor A, David L, Fowlkes J, Blackledge MT, Martin TM, Planck SR, Rosenzweig HL, Rosenbaum JT, Davey MP
Molecular Immunology 47, 2009, 560-566


Influence of polymorphisms in porcine NOD2 on ligand recognition
Jozaki K, Shinkai H, Tanaka-Matsuda M, Morozumi T, Matsumoto T, Toki D, Okumura N, Eguchi-Ogawa T, Kojima-Shibata C, Kadowaki H, Suzuki E, Wada Y, Uenishi H
Molecular Immunology 47, 2009, 247-252


Genomewide Association Study of Leprosy
Zhang FR, Huang W, Chen SM, Sun LD, Liu H, Li Y, Cui Y, Yan XX, Yang HT, Yang RD, Chu TS, Zhang C, Zhang L, Han JW, Yu GQ, Quan C, Yu YX, Zhang Z, Shi BQ, Zhang LH, Cheng H, Wang CY, Lin Y, Zheng HF, Fu XA, Zuo XB, Wang Q, Long H, Sun YP, Cheng YL, Tian HQ, Zhou FS, Liu HX, Lu WS, He SM, Du WL, Shen M, Jin QY, Wang Y, Low HQ, Erwin T, Yang NH, Li JY, Zhao X, Jiao YL, Mao LG, Yin G, Jiang ZX, Wang XD, Yu JP, Hu ZH, Gong CH, Liu YQ, Liu RY, Wang DM, Wei D, Liu JX, Cao WK, Cao HZ, Li YP, Yan WG, Wei SY, Wang KJ, Hibberd ML, Yang S, Zhang XJ, Liu JJ
New England Journal of Medicine 361, 2009, 2609-2618


Uveitis in a Patient Treated with Bacille-Calmette-Guerin Possible Antigenic Mimicry of Mycobacterial and Retinal Antigens
Garip A, edrichs-Mohring M, Thurau SR, Deeg CA, Wildner G
Ophthalmology 116, 2009, 2457-2462


A case of acute and necrotizing cutaneous Mycobacterium marinum infection in a patient treated with infliximab for Crohn's disease
Guyot A, Begon E, Abramowitz L, Landry J, Marinho E, Descamps V, Crickx B
Annales de Dermatologie et de Venereologie 136, 2009, 806-810


Intranasal Immunization Promotes Th17 Immune Responses
Zygmunt BM, Rharbaoui F, Groebe L, Guzman CA
Journal of Immunology 183, 2009, 6933-6938


NOD2 Ligation Subverts IFN-alpha Production by Liver Plasmacytoid Dendritic Cells and Inhibits Their T Cell Allostimulatory Activity via B7-H1 Up-Regulation
Castellaneta A, Sumpter TL, Chen LP, Tokita D, Thomson AW
Journal of Immunology 183, 2009, 6922-6932


A New Avenue to Investigate: the Autophagic Process. from Crohn'S Disease to Chlamydia
Pena AS, Karimi O, Crusius JBA
Drugs of Today 45, 2009, 113-117


Occurrence of Mycobacterium avium subspecies paratuberculosis across host species and European countries with evidence for transmission between wildlife and domestic ruminants
Stevenson K, Alvarez J, Bakker D, Biet F, De Juan L, Denham S, Dimareli Z, Dohmann K, Gerlach GF, Heron I, Kopecna M, May L, Pavlik I, Sharp JM, Thibault VC, Willemsen P, Zadoks RN, Greig A
Bmc Microbiology 9, 2009, Article Number: 212 Published: OCT 7 2009


Nod2 Mutation Enhances NF-kappaB Activity and Bacterial Killing Activity of Macrophages
Tsay TB, Chang CJ, Chen PH, Hsu CM, Chen LW
Inflammation 32, 2009, 372-378


MDP-Induced Selective Tolerance to TLR4 Ligands: Impairment in NOD2 Mutant Crohn's Disease Patients
Canto E, Moga E , Ricart E, Garcia-Bosch O, Garcia-Planella E, Juarez C, Vidal S
Inflammatory Bowel Diseases 15, 2009, 1686-1696


Mycobacterium avium Subspecies paratuberculosis in Children with Early-Onset Crohn's Disease
Kirkwood CD, Wagner J, Boniface K, Vaughan J, Michalski WP, Catto-Smith AG, Cameron DJS, Bishop RF
Inflammatory Bowel Diseases 15, 2009, 1643-1655


Effects of interactions of antibacterial drugs with each other and with 6-mercaptopurine on in vitro growth of Mycobacterium avium subspecies paratuberculosis
Krishnan MY, Manning EJB, Collins MT
Journal of Antimicrobial Chemotherapy 64, 2009, 1018-1023


Low prevalence of NOD2 SNPs in Behcet's disease suggests protective association in Caucasians
Kappen JH, Wallace GR, Stolk L, Rivadeneira F, Uitterlinden AG, van Daele PLA, Laman JD, Kuijpers RWAM, Baarsma GS, Stanford MR, Fortune F, Madanat W, van Hagen PM, van Laar JAM
Rheumatology 48, 2009, 1375-1377


Internalization-dependent recognition of Mycobacterium avium ssp paratuberculosis by intestinal epithelial cells
Pott J, Basler T, Duerr CU, Rohde M, Goethe R, Hornef MW
Cellular Microbiology 11, 2009, 1802-1815


Autoimmune T cell responses to antigenic peptides presented by bronchoalveolar lavage cell HLA-DR molecules in sarcoidosis
Wahlstrom J, Dengjel J, Winqvist O, Targoff I, Persson B, Duyar H, Rammensee HG, Eklund A, Weissert R, Grunewald J
Clinical Immunology 133, 2009, 353-363


The Common Mycobacterial Antigens and their Importance in the Treatment of Disease
Stanford J, Stanford C, Stansby G, Bottasso O, Bahr G, Grange J
Current Pharmaceutical Design 15, 2009, 1248-1260


Mycobacterium avium subsp paratuberculosis and M-a. avium Detected by Culture, IS900 and IS901 Highly Sensitive PCR in Bulk Tank Milk from Dairy Herds in the Czech Republic between 2002 and 2004
Slana I, Bartos M, Roubal P, Babak V, Pavlik I
Czech Journal of Food Sciences 27, 2009, 372-378


Therapy- and Non-Therapy-Dependent Infectious Complications in Inflammatory Bowel Disease
Epple HJ
Digestive Diseases 27, 2009, 555-559


Crohn Disease and Mycobacterial Infection in Children: An Intriguing Relationship
Chiappini E, de Martino M, Mangiantini F, Lionetti P
Journal of Pediatric Gastroenterology and Nutrition 49, 2009, 550-558


The Methodological Soundness of Literature Reviews Addressing Three Potential Zoonotic Public Health Issues
Waddell L, Rajic A, Sargeant J, Parker S, Deckert A, McEwen S
Zoonoses and Public Health 56, 2009, 477-489


Production of and applications for a polyclonal IgY diagnostic reagent specific for Mycobacterium avium subsp paratuberculosis
Shin SJ, Lee SS , Manning EJB, Collins MT
Journal of Microbiology 47, 2009, 600-609


Psoriasis - as an autoimmune disease caused by molecular mimicry
Valdimarsson H, Thorleifsdottir RH, Sigurdardottir SL, Gudjonsson JE, Johnston A
Trends in Immunology 30, 2009, 494-501


The determinants of susceptibility/resistance to adjuvant arthritis in rats
Kim EY, Moudgil KD
Arthritis Research & Therapy 11, 2009, Issue 4, Article No. 239


Infectious Serologies and Autoantibodies in Inflammatory Bowel Disease Insinuations at a True Pathogenic Role
Lidar M, Langevitz P, Barzilai O, Ram M, Porat-Katz BS, Bizzaro N, Tonutti E, Maieron R, Chowers Y, Bar-Meir S, Shoenfeld Y
Contemporary Challenges in Autoimmunity 1173, 2009, 640-648


Il-32: A Newly-Discovered Proinflammatory Cytokine
Felaco P, Castellani ML, De Lutiis MA, Felaco M, Pandolfi F, Salini V, De Amicis D, Vecchiet J, Tete S, Ciampoli C, Conti F, Cerulli G, Caraffa A, Antinolfi P, Cuccurullo C, Perrella A, Theoharides TC, Conti P, Toniato E, Kempuraj D, Shaik YB
Journal of Biological Regulators and Homeostatic Agents 23, 2009, 141-147


MAIL Regulates Human Monocyte IL-6 Production
Seshadri S, Kannan Y, Mitra S, Parker-Barnes J, Wewers MD
Journal of Immunology 183, 2009, 5358-5368


PepT1 Oligopeptide Transporter (SLC15A1) Gene Polymorphism in Inflammatory Bowel Disease
Zucchelli M, Torkvist L, Bresso F, Halfvarson J, Hellquist A, Anedda F, Assadi G, Lindgren GB, Svanfeldt M, Janson M, Noble CL, Pettersson S, Loppalainen M , Paavola-Sakki P, Halme L, Farkkila M, Turunen U, Satsangi J, Kontula K, Lofberg R, Kere J, D'Amato M
Inflammatory Bowel Diseases 15, 2009, 1562-1569


The Role of Infection in Inflammatory Bowel Disease: Initiation, Exacerbation and Protection
Lidar M, Langevitz P, Shoenfeld Y
Israel Medical Association Journal 11, 2009, 558-563


Engagement of TLR2 Does not Reverse the Suppressor Function of Mouse Regulatory T Cells, but Promotes Their Survival
Chen Q, Davidson TS, Huter EN, Shevach EM
Journal of Immunology 183, 2009, 4458-4466


Role of Nod2 in the development of Crohn's disease
Yamamoto S, Ma XJ
Microbes and Infection 11, 2009, 912-918


Adaptive Regulation at the Cell Surface by N-Glycosylation
Dennis JW, Lau KS, Demetriou M, Nabi IR
Traffic 10, 2009, 1569-1578


Links between Autophagy, Innate Immunity, Inflammation and Crohn's Disease
Deretic V
Digestive Diseases 27, 2009, 246-251


Environmental Factors Affecting Inflammatory Bowel Disease: Have We Made Progress?
Lakatos PL
Digestive Diseases 27, 2009, 215-225


Disease Behavior in Adult Patients: Are There Predictors for Stricture or Fistula Formation?
Dotan I
Digestive Diseases 27, 2009, 206-211


A close look at human IgG sialylation and subclass distribution after lectin fractionation
Stadlmann J, Weber A, Pabst M, Anderle H, Kunert R, Ehrlich HJ, Schwarz HP, Altmann F
Proteomics 9, 2009, 4143-4153


Short communication: Progression of Johne's disease curtailed by a probiotic
Click RE, Van Kampen CL
Journal of Dairy Science 92, 2009, 4846-4851


New insights into the pathogenesis of Crohn's disease: are they relevant for therapeutic options?
Vavricka SR, Rogler G
Swiss Medical Weekly 139, 2009, 527-534


Contamination of food products with Mycobacterium avium paratuberculosis: a systematic review4
Eltholth MM, Marsh VR, Van Winden S, Guitian FJ
Journal of Applied Microbiology 107, 2009, 1061-1071


Debugging the intestinal microbiota in IBD
Dessein R, Rosenstiel P, Chamaillard M
Gastroenterologie Clinique et Biologique 33, 2009, S131-S136


Prevalence and distribution of paratuberculosis (Johne's disease) in cattle herds in Ireland
Good M, Clegg T , Sheridan H, Yearsely D, O'Brien T, Egan J, Mullowney P
Irish Veterinary Journal 62, 2009, 597-606


DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses
Lipinski S, Till A, Sina C, Arlt A, Grasberger H, Schreiber S, Rosenstiel P
Journal of Cell Science 122, 2009, 3522-3530


Aberrant TGF-beta signaling reduces T regulatory cells in ICAM-1-deficient mice, increasing the inflammatory response to Mycobacterium tuberculosis
Windish HP, Lin PL, Mattila JT, Green AM, Onuoha EO, Kane LP, Flynn JL
Journal of Leukocyte Biology 86, 2009, 713-725


NOD-Like Receptors-Pivotal Guardians of the Immunological Integrity of Barrier Organs
Rosenstiel P, Schreiber S
Target Pattern Recognition in Innate Immunity 653, 2009, 35-47


Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa
Khader SA, Gaffen SL, Kolls JK
Mucosal Immunology 2 , 2009, 403-411


ITCH K63-Ubiquitinates the NOD2 Binding Protein, RIP2, to Influence Inflammatory Signaling Pathways
Tao MF, Scacheri PC, Marinis JM, Harhaj EW, Matesic LE, Abbott DW
Current Biology 19, 2009, 1255-1263


Peptidoglycan from lactobacilli inhibits interleukin-12 production by macrophages induced by Lactobacillus casei through Toll-like receptor 2-dependent and independent mechanisms
Shida K, Kiyoshima-Shibata J, Kaji R, Nagaoka M, Nanno M
Immunology 128, 2009, e858-e869


A component of polysaccharide peptidoglycan complex on Lactobacillus induced an improvement of murine model of inflammatory bowel disease and colitis-associated cancer
Matsumoto S, Hara T, Nagaoka M, Mike A, Mitsuyama K, Sako T, Yamamoto M, Kado S, Takada T
Immunology 128, 2009, e170-e180


NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation
Hruz P, Zinkernagel AS, Jenikova G, Botwin GJ, Hugot JP, Karin M, Nizet V, Eckmann L
Proceedings of the National Academy of Sciences of the United States of America 106, 2009, 12873-12878


Increased NOD2-mediated recognition of N-glycolyl muramyl dipeptide
Coulombe F, Divangahi M, Veyrier F, de LL, Gleason JL, Yang Y, Kelliher MA, Pandey AK, Sassetti CM, Reed MB, Behr MA
J Exp.Med 206, 3-8-2009, 1709-1716


NOD-Like Receptors: Role in Innate Immunity and Inflammatory Disease
Chen G, Shaw MH , Kim YG, Nunez G
Annual Review of Pathology-Mechanisms of Disease 4, 2009, 365-398


Evolution and Function of Innate Immune Receptors - Insights from Marine Invertebrates
Rosenstiel P, Philipp EER, Schreiber S, Bosch TCG
Journal of Innate Immunity 1, 2009, 291-300


'One Health', from science to policy: examples from the Israeli experience
Klement E, Shpigel N, Balicer RD, Baneth G, Grotto I, Davidovitch N
Veterinaria Italiana 45, 2009, 45-53


Modulation of muramyl dipeptide stimulation of cytokine production by blood components
van der Meer JHM, Netea MG, Dinarello CA
Clinical and Experimental Immunology 156, 2009, 428-433


Multiple regulatory and effector roles of autophagy in immunity
Deretic V
Current Opinion in Immunology 21, 2009, 53-62


Commensal bacteria, traditional and opportunistic pathogens, dysbiosis and bacterial killing in inflammatory bowel diseases
Packey CD, Sartor RB
Current Opinion in Infectious Diseases 22, 2009, 292-301


Combined Polymorphisms in Genes Encoding the Inflammasome Components NALP3 and CARD8 Confer Susceptibility to Crohn's Disease in Swedish Men
Schoultz I, Verma D, Halfvarsson J, Torkvist L, Fredrikson M, Sjoqvist U, Lordal M, Tysk C, Lerm M, Soderkvist P, Soderholm JD
American Journal of Gastroenterology 104, 2009, 1180-1188


Where Are All the Mycobacterium avium Subspecies paratuberculosis in Patients with Crohn's Disease?
Pierce ES
Plos Pathogens 5, 2009, Article Number: e1000234 Published: MAR 2009


Siglecs as targets for therapy in immune-cell-mediated disease
O'Reilly MK, Paulson JC
Trends in Pharmacological Sciences 30, 2009, 240-248


Interleukin-25 Inhibits Interleukin-12 Production and Th1 Cell-Driven Inflammation in the Gut
Caruso R, Sarra M, Stolfi C, Rio A, Fina D, Fantini MC, Pallone F, MacDonald TT, Monteleone G
Gastroenterology 136, 2009, 2270-2279


Novel Anti-Glycan Antibodies Related to Inflammatory Bowel Disease Diagnosis and Phenotype
Seow CH, Stempak JM, Xu W, Lan H, Griffiths AM, Greenberg GR, Steinhart AH, Dotan N, Silverberg MS
American Journal of Gastroenterology 104, 2009, 1426-1434


Can infections protect against autoimmunity?
Gaisford W, Cooke A
Current Opinion in Rheumatology 21, 2009, 391-396


Anti glycans antibodies establish an unexpected link between C. albicans and Crohn disease
Sendid B, Jouault T, Vitse A, Fradin C, Colombel JF, Poulain D
M S-Medecine Sciences 25, 2009, 473-481


Autophagy, Immunity, and Microbial Adaptations
Deretic V, Levine B
Cell Host & Microbe 5, 2009, 527-549


Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2
Bertrand MJM, Doiron K, Labbe K, Korneluk RG, Barker PA, Saleh M
Immunity 30, 2009, 789-801


Toll-like receptors in control of immunological autophagy
Delgado MA, Deretic V
Cell Death and Differentiation 16, 2009, 976-983


Mannose-binding lectin and innate immunity
Ip WKE, Takahashi K, Ezekowitz RA, Stuart LM
Immunological Reviews 230, 2009, 9-21


Infection and type 1 diabetes mellitus - A two edged sword?
Goldberg E, Krause I
Autoimmunity Reviews 8, 2009, 682-686


Autoimmune disease in the era of the metagenome
Proal AD, Albert PJ, Marshall T
Autoimmunity Reviews 8, 2009, 677-681


The Kinase Activity of Rip2 Determines Its Stability and Consequently Nod1-and Nod2-mediated Immune Responses
Nembrini C, Kisielow J, Shamshiev AT, Tortola L , Coyle AJ, Kopf M, Marsland BJ
Journal of Biological Chemistry 284, 2009, 19183-19188


Immunohistochemical detection of NOD1 and NOD2 in the healthy murine and canine eye
Scurrell E, Stanley R, Schoniger S
Veterinary Ophthalmology 12, 2009, 269-275


Autophagy genes in immunity
Virgin HW, Levine B
Nature Immunology 10, 2009, 461-470


Crohn's disease-associated Nod2 mutants reduce IL10 transcription
Philpott DJ, Girardin SE
Nature Immunology 10, 2009, 455-457


Anti-TNF immunotherapy reduces CD8(+) T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans
Bruns H, Meinken C, Schauenberg P, Harter G, Kern P, Modlin RL, Antoni C, Stenger S
Journal of Clinical Investigation 119, 2009, 1167-1177


Anti-TNF immunotherapy and tuberculosis reactivation: another mechanism revealed
Miller EA, Ernst JD
Journal of Clinical Investigation 119, 2009, 1079-1082


Differentiating Intestinal Tuberculosis From Crohn's Disease: A Diagnostic Challenge
Almadi MA, Ghosh S, Aljebreen AM
American Journal of Gastroenterology 104, 2009, 1003-1012


Heat-shock proteins can promote as well as regulate autoimmunity
Rajaiah R, Moudgil KD
Autoimmunity Reviews 8, 2009, 388-393


TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA
Chockalingam A, Brooks JC, Cameron JL, Blum LK, Leifer CA
Immunology and Cell Biology 87, 2009, 209-217


Association between Mycobacterium avium subsp paratuberculosis DNA in blood and cellular and humoral immune response in inflammatory bowel disease patients and controls
Juste RA, Elguezabal N, Pavon A, Garrido JM, Geijo M, Sevilla I, Cabriada JL, Tejada A, Garcia-Campos F, Casado R, Ochotorena I, Izeta A
International Journal of Infectious Diseases 13, 2009, 247-254


Genomic Comparison of PE and PPE Genes in the Mycobacterium avium Complex
Mackenzie N, Alexander DC, Turenne CY, Behr MA, De Buck JM
Journal of Clinical Microbiology 47, 2009, 1002-1011


No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis
Jaen O, Petit-Teixeira E, Kirsten H, Ahnert P, Semerano L, Pierlot C, Cornelis F, Boissier MC, Falgarone G
Arthritis Research & Therapy 11, 2009, Article Number: R5


NOD1 Expression in the Eye and Functional Contribution to IL-1 beta-Dependent Ocular Inflammation in Mice
Rosenzweig HL, Galster KT, Planck SR, Rosenbaum JT
Investigative Ophthalmology & Visual Science 50, 2009, 1746-1753


Nucleotide Oligomerization Domain-2 (NOD2)-Induced Uveitis: Dependence on IFN-gamma
Rosenzweig HL, Kawaguchi T, Martin TM, Planck SR, Davey MP, Rosenbaum JT
Investigative Ophthalmology & Visual Science 50, 2009, 1739-1745


Clathrin- and Dynamin-Dependent Endocytic Pathway Regulates Muramyl Dipeptide Internalization and NOD2 Activation
Marina-Garcia N, Franchi L, Kim YG, Hu YJ, Smith DE, Boons GJ, Nunez G
Journal of Immunology 182, 2009, 4321-4327


Mycobacterium avium subspecies paratuberculosis suppresses expression of IL-12p40 and NOS genes induced by signalling through CD40 in bovine monocyte-derived macrophages
Sommer S, Pudrith CB, Colvin CJ, Coussens PM
Veterinary Immunology and Immunopathology 128, 2009, 44-52


Modulatory Effects of Tuberculosis Vaccines on Experimental Autoimmune Encephalomyelitis
Zorzella-Pezavento SFG
Journal of Venomous Animals and Toxins Including Tropical Diseases 15, 2009, 180


The Contribution of y delta T Cells to the Pathogenesis of EAE and MS
Blink SE, Miller SD
Current Molecular Medicine 9, 2009, 15-22


Pancreatic Autoantibodies Are Associated with Reactivity to Microbial Antibodies, Penetrating Disease Behavior, Perianal Disease, and Extraintestinal Manifestations, But Not with NOD2/CARD15 or TLR4 Genotype in a Hungarian IBD Cohort
Lakatos PL, Altorjay I, Szamosi T, Palatka K, Vitalis Z, Tumpek J, Sipka S, Udvardy M, Dinya T, Lakatos L, Kovacs A, Molnar T, Tulassay Z, Miheller P, Barta Z, Stocker W, Papp J, Veres G, Papp M
Inflammatory Bowel Diseases 15, 2009, 365-374


QuantiFERON-TB Gold and the TST are both useful for latent tuberculosis infection screening in autoimmune diseases
Bartalesi F, Vicidomini S, Goletti D, Fiorelli C, Fiori G, Melchiorre D, Tortoli E, Mantella A, Benucci M, Girardi E, Cerinic MM, Bartoloni A
European Respiratory Journal 33, 2009, 586-593


PGLYRP-2 and Nod2 Are Both Required for Peptidoglycan-Induced Arthritis and Local Inflammation
Saha S, Qi J, Wang SY, Wang MH, Li XN, Kim YG, Nunez G, Gupta D, Dziarski R
Cell Host & Microbe 5, 2009, 137-150


Identification of the most active interleukin-32 isoform
Choi JD, Bae SY , Hong JW, Azam T, Dinarello CA, Her E, Choi WS, Kim BK, Lee CK, Yoon DY, Kim SJ, Kim SH
Immunology 126, 2009, 535-542


Autoimmune lymphoproliferative syndrome-like syndrome presented as lupus-like syndrome with mycobacterial joint infection evolved into the lymphoma
Hong YH, Lee CK
Rheumatology International 29, 2009, 569-573


Recent advances in DNA vaccines for autoimmune diseases
Silva CL, Bonato VLD, dos Santos RR, Zarate-Blades CR, Sartori A
Expert Review of Vaccines 8, 2009, 239-252


Expression, Regulation, and Signaling of the Pattern-Recognition Receptor Nucleotide-Binding Oligomerization Domain 2 in Rheumatoid Arthritis Synovial Fibroblasts
Ospelt C, Brentano F, Jungel A, Rengel Y, Kolling C, Michel BA, Gay RE, Gay S
Arthritis and Rheumatism 60, 2009, 355-363


Differences in distribution of single nucleotide polymorphisms among intracellular pattern recognition receptors in pigs
Kojima-Shibata C, Shinkai H, Morozumi T, Jozaki K , Toki D, Matsumoto T, Kadowaki H, Suzuki E, Uenishi H
Immunogenetics 61, 2009, 153-160


Mycobacterial coxitis masked by concomitant staphylococcal infection after infliximab for Crohn's disease
Dhawan SS, Finks AL, Wang BWE
Joint Bone Spine 76, 2009, 107-108


Toll-like receptor-induced granulocyte-macrophage colony-stimulating factor secretion is impaired in Crohn's disease by nucleotide oligomerization domain 2-dependent and -independent pathways
Brosbol-Ravnborg A, Hvas CL, Agnholt J, Dahlerup JF, Vind I, Till A, Rosenstiel P, Hollsberg P
Clinical and Experimental Immunology 155, 2009, 487-495


Hyperexpression of NOD2 in intestinal mast cells of Crohn's disease patients: Preferential expression of inflammatory cell-recruiting molecules via NOD2 in mast cells
Okumura S, Yuki K, Kobayashi R, Okamura S, Ohmori K, Saito H, Ra C, Okayama Y
Clinical Immunology 130, 2009, 175-185


NOD2 Plays an Important Role in the Inflammatory Responses of Microglia and Astrocytes to Bacterial CNS Pathogens
Chauhan VS, Sterka DG, Furr SR, Young AB, Marriott I
Glia 57, 2009, 414-423


Alteration of N-glycosylation in the kidney in a mouse model of systemic lupus erythematosus: relative quantification of N-glycans using an isotope-tagging method
Hashii N, Kawasaki N, Itoh S, Nakajima Y, Kawanishi T, Yamaguchi T
Immunology 126, 2009, 336-345


Discovery of Stable and Variable Differences in the Mycobacterium avium subsp paratuberculosis Type I, II, and III Genomes by Pan-Genome Microarray Analysis
Castellanos E, Aranaz A, Gould KA, Linedale R, Stevenson K, Alvarez J, Dominguez L, De Juan L, Hinds J, Bull TJ
Applied and Environmental Microbiology 75, 2009, 676-686


Mycobacterium avium subspecies paratuberculosis and its relationship with Crohn's disease
Mendoza JL, Lana R, Diaz-Rubio M
World Journal of Gastroenterology 15, 2009, 417-422


Bacteria and Primary Biliary Cirrhosis
Bogdanos DP, Vergani D
Clinical Reviews in Allergy & Immunology 36, 2009, 30-39


Insertion and Deletion Events That Define the Pathogen Mycobacterium avium subsp paratuberculosis
Alexander DC, Turenne CY, Behr MA
Journal of Bacteriology 191, 2009, 1018-1025


The role of interferon gamma in regulation of CD4(+) T-cells and its clinical implications
Chen JZ, Liu XS
Cellular Immunology 254, 2009, 85-90


Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens
Curtis MM, Way SS
Immunology 126, 2009, 177-185


TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4
Ito T, Schaller M, Hogaboam CM, Standiford TJ, Sandor M, Lukacs NW, Chensue SW, Kunkel SL
Journal of Clinical Investigation 119, 2009, 33-46


Mycobacterium avium paratuberculosis Invades Human Small-Intestinal Goblet Cells and Elicits Inflammation
Golan L, Livneh-Kol A, Gonen E, Yagel S, Rosenshine I, Shpigel NY
Journal of Infectious Diseases 199, 2009, 350-354


Evaluation of immune responses and protective efficacy in a goat model following immunization with a coctail of recombinant antigens and a polyprotein of Mycobacterium avium subsp paratuberculosis
Kathaperumal K, Kumanan V, McDonough S, Chen LH, Park SU, Moreira MAS, Akey B, Huntley J, Chang CF, Chang YF
Vaccine 27, 2009, 123-135


Role of the NOD2 Genotype in the Clinical Phenotype of Blau Syndrome and Early-Onset Sarcoidosis
Okafuji I, Nishikomori R, Kanazawa N, Kambe N, Fujisawa A, Yamazaki S, Saito M, Yoshioka T, Kawai T, Sakai H, Tanizaki H, Heike T, Miyachi Y, Nakahata T
Arthritis and Rheumatism 60, 2009, 242-250


Tolerization With Hsp65 Induces Protection Against Adjuvant-Induced Arthritis by Modulating the Antigen-Directed Interferon-gamma, Interleukin-17, and Antibody Responses
Satpute SR, Rajaiah R, Polumuri SK, Moudgil KD
Arthritis and Rheumatism 60, 2009, 103-113


Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit
Henckaerts L, Nielsen KR, Steffensen R, Van Steen K, Mathieu C, Giulietti A, Wouters PJ, Milants I, Vanhorebeek I, Langouche L, Vermeire S, Rutgeerts P, Thiel S, Wilmer A, Hansen TK, Van den Berghe G
Critical Care Medicine 37, 2009, 192-201


Intestinal bacteria and inflammatory bowel disease
Macfarlane S, Steed H, Macfarlane GT
Critical Reviews in Clinical Laboratory Sciences 46, 2009, 25-54


Autophagy and pattern recognition receptors in innate immunity
Delgado M, Singh S, De Haro S, Master S, Ponpuak M, Dinkins C, Ornatowski W, Vergne I, Deretic V
Immunological Reviews 227, 2009, 189-202


PrFont34Bin0BinSub0Frac0Def1Margin0Margin0Jc1Indent1440Lim0Lim1 zkusm Function of Nod-like receptors in microbial recognition and host defense
Franchi L, Wamer N, Viani K, Nunez G
Immunological Reviews 227, 2009, 106-128


Quantitative Dynamic Models of Arthritis Progression in the Rat
Earp J, DuBois D, Almon R, Jusko W
Pharmaceutical Research 26, 2009, 196-203


Immune Reconstitution Inflammatory Syndrome: A Reappraisal
French MA
Clinical Infectious Diseases 48, 2009, 101-107


Macrophage migration inhibitory factor stimulates interleukin-17 expression and production in lymph node cells
Stojanovic I, Cvjeticanin T, Lazaroski S, Stosic-Grujicic S, Miljkovic D
Immunology 126, 2009, 74-83


New Serological Markers for Inflammatory Bowel Disease Are Associated With Earlier Age at Onset, Complicated Disease Behavior, Risk for Surgery, and NOD2/CARD15 Genotype in a Hungarian IBD Cohort
Papp M, Altorjay I, Dotan N, Palatka K, Foldi I, Tumpek J, Sipka S, Udvardy M, Dinya T, Lakatos L, Kovacs A, Molnar T, Tulassay Z, Miheller P, Norman GL, Szamosi T, Papp J, Lakatos PL
American Journal of Gastroenterology 103, 2008, 665-681


Glyco-biomarkers: Potential determinants of cellular physiology and pathology
Alavi A, Axford JS
Disease Markers 25, 2008, 193-205


Interplay Between Effector Th17 and Regulatory T Cells
Awasthi A, Murugaiyan G, Kuchroo VK
Journal of Clinical Immunology 28, 2008, 660-670


NOD2 engagement induces proinflammatory cytokine production, but not apoptosis, in leukocytes isolated from patients with Crohn's disease
Bodar E, Netea MG, de Jong DJ, Kullberg BJ, Joosten LAB, van der Meer JWM
European Cytokine Network 19, 2008, 185-189


Genetic and Metabolic Regulation of N-glycan GlcNAc Branching and Autoimmunity
Demetriou M
Glycobiology 18, 2008, 31


Lectin-epithelial interactions in the human colon
Rhodes JM, Campbell BJ, Yu LG
Biochemical Society Transactions 36, 2008, 1482-1486


The impact of treatment with tumour necrosis factor-alpha antagonists on the course of chronic viral infections: a review of the literature
Domm S, Cinatl J, Mrowietz U
British Journal of Dermatology 159, 2008, 1217-1228


Nucleic Acid from Saliva and Salivary Cells for Noninvasive Genotyping of Crohn's Disease Patients
Hong JW, Leung E, Fraser A, Krissansen GW
Genetic Testing 12, 2008, 587-589


Identification of a receptor required for the anti-inflammatory activity of IVIG
Anthony RM, Wermeling F, Karlsson MCI, Ravetch JV
Proceedings of the National Academy of Sciences of the United States of America 105, 2008, 19571-19578


In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner
Albert H, Collin M, Dudziak D, Ravetch JV, Nimmerjahn F
Proceedings of the National Academy of Sciences of the United States of America 105, 2008, 15005-15009


Systemic lupus erythematosus association with tuberculosis - Critical review
Pereira JCB
Revista Portuguesa de Pneumologia 14, 2008, 843-855


Qa-1/HLA-E-restricted regulatory CD8+ T cells and self-nonself discrimination: An essay on peripheral T-cell regulation
Jiang H, Chess L
Human Immunology 69, 2008, 721-727


Potential Pathogenic Role of Mycobacterium avium Subspecies paratuberculosis in Crohn's Disease
Shafran I, Burgunder P
Inflammatory Bowel Diseases 14, 2008, 1753-1755


Mycobacterium avium paratuberculosis in children with early onset Crohn's disease
Kirkwood CD, Wagner J, Boniface K, Vaughan J, Michalski WP, Catto-Smith AG, Cameron DJS, Bishop RF
Journal of Gastroenterology and Hepatology 23, 2008, A299


Transcriptional analysis of diverse strains Mycobacterium avium subspecies paratuberculosis in primary bovine monocyte derived macrophages
Zhu XC, Tu ZJ, Coussens PM, Kapur V, Janagama H, Naser S, Sreevatsan S
Microbes and Infection 10, 2008, 1274-1282


Applications of flow cytometry for the study of primary immune deficiencies
Oliveira JB, Notarangelo LD, Fleisher TA
Current Opinion in Allergy and Clinical Immunology 8, 2008, 499-509


Combined Multilocus Short-Sequence-Repeat and Mycobacterial Interspersed Repetitive Unit-Variable-Number Tandem-Repeat Typing of Mycobacterium avium subsp paratuberculosis Isolates
Thibault VC, Grayon M, Boschiroli ML, Willery E, lix-Beguec C, Stevenson K, Biet F, Supply P
Journal of Clinical Microbiology 46, 2008, 4091-4094


Nod2-Dependent Th2 Polarization of Antigen-Specific Immunity
Magalhaes JG, Fritz JH, Le Bourhis L, Sellge G, Travassos LH, Selvanantham T, Girardin SE, Gommerman JL, Philpott DJ
Journal of Immunology 181, 2008, 7925-7935


Tumor Necrosis Factor Blockers Influence Macrophage Responses to Mycobacterium tuberculosis
Harris J, Hope JC, Keane J
Journal of Infectious Diseases 198, 2008, 1842-1850


Experimental induction of salt-sensitive hypertension is associated with lymphocyte proliferative response to HSP70
Parra G, Quiroz Y, Salazar J, Bravo Y, Pons H, Chavez M, Johnson RJ, Rodriguez-Iturbe B
Kidney International 74, 2008, S55-S59


Cows, Crohn's and more: Is Mycobacterium paratuberculosis a superantigen?
Dow CT
Medical Hypotheses 71, 2008, 858-861


Recurrent pericarditis: Infectious or autoimmune?
Brucato A, Maestroni S, Cumetti D, Thiella G, Alaria G, Brambilla G, Imazio M, Doria A, Palmieri G, Adler Y
Autoimmunity Reviews 8, 2008, 44-47


Infections as triggers and complications of systemic lupus erythematosus
Doria A, Canova M, Tonon M, Zen M, Rampudda E, Bassi N, Atzeni F, Zampieri S, Ghirardello A
Autoimmunity Reviews 8, 2008, 24-28


Innate immune signalling at intestinal mucosal surfaces: a fine line between host protection and destruction
Cario E
Current Opinion in Gastroenterology 24, 2008, 725-732


Bacterial infection alters the kinetics and function of iNKT cell responses
Choi HJ, Xu HL, Geng YB, Colmone A, Cho H, Wang CR
Journal of Leukocyte Biology 84, 2008, 1462-1471


Structural and Functional Aspects of Lipid Binding by CD1 Molecules
Silk JD, Salio M, Brown J, Jones EY, Cerundolo V
Annual Review of Cell and Developmental Biology 24, 2008, 369-395


Current Mycobacterium: what's on tomorrow's menu?
Behr MA
Microbes and Infection 10, 2008, 968-972


Clinical and Pathological Similarities Between Paratuberculosis and Crohn'S Disease. ?A Possible Zoonotic Link?
Calderon J, Gongora A
Revista Mvz Cordoba 13, 2008, 1226-1239


Inflammatory bowel disease (IBD) serological markers
Benkhadra F, Humbel RL
Immuno-Analyse & Biologie Specialisee 23, 2008, 202-211


Mycobacterium avium subspecies induce differential expression of pro-inflammatory mediators in a murine macrophage model: Evidence for enhanced pathogenicity of Mycobacterium avium subspecies paratuberculosis
Basler T, Geffers R, Weiss S, Valentin-Weigand P , Goethe R
Immunobiology 213, 2008, 879-888


Reconciling id, ego, and superego within interleukin-23
Tato CM, Cua DJ
Immunological Reviews 226, 2008, 103-111


Causality and gastrointestinal infections: Koch, Hill, and Crohn's
Lowe AM, Yansouni CP, Behr MA
Lancet Infectious Diseases 8, 2008, 720-726


Does a mycobacterial infection cause Crohn's disease?
Kathryn S
Lancet Infectious Diseases 8, 2008, 671


The molecular basis of NOD2 susceptibility mutations in Crohn's disease
Strober W, Kitani A, Fuss I, Asano N, Watanabe T
Mucosal Immunology 1, 2008, S5-S9


How interferon-gamma keeps autoimmune diseases in check
Kelchtermans H, Billiau A, Matthys P
Trends in Immunology 29, 2008, 479-486


Autophagy, an immunologic magic bullet: Mycobacterium tuberculosis phagosome maturation block and how to bypass it
Deretic V
Future Microbiology 3, 2008, 517-524


Antigen-specific regulatory T cells in bovine paratuberculosis
de Almeida DE, Colvin CJ, Coussens PA
Veterinary Immunology and Immunopathology 125, 2008, 234-245


Is Mycobacterium paratuberculosis or Any Other Infectious Agent Involved in the Pathogenesis of IBD?
Van Kruiningen HJ
Inflammatory Bowel Diseases 14, 2008, S88-S89


Impact of glycans on T-cell tolerance to glycosylated self-antigens
Purcell AW, van Driel IR, Gleeson PA
Immunology and Cell Biology 86, 2008, 574-579


Green Tea Protects Rats against Autoimmune Arthritis by Modulating Disease-Related Immune Events
Kim HR, Rajaiah R, Wu QL, Satpute SR, Tan MT, Simon JE, Berman BM, Moudgil KD
Journal of Nutrition 138, 2008, 2111-2116


Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival
Cruickshank SM, Wakenshaw L, Cardone J, Howdle PD , Murray PJ, Carding SR
World Journal of Gastroenterology 14, 2008, 5834-5841


Aberrant Innate Immune Responses in TLR-ligand Activated HLA-B27 Transgenic Rat Cells
Qian BF, Tonkonogy SL, Sartor RB
Inflammatory Bowel Diseases 14 , 2008, 1358-1365


Tumour necrosis factor antagonists: structure, function, and tuberculosis risks
Walls RS
Lancet Infectious Diseases 8, 2008, 601-611


Innate immunity and intestinal microbiota in the development of Type 1 diabetes
Wen L, Ley RE, Volchkov PY, Stranges PB, Avanesyan L, Stonebraker AC, Hu CY, Wong FS, Szot GL, Bluestone JA, Gordon JI, Chervonsky AV
Nature 455, 2008, 1109-1U10


MEKK4 sequesters RIP2 to dictate NOD2 signal specificity
Clark NM, Marinis JM, Cobb BA, Abbott DW
Current Biology 18, 2008, 1402-1408


Biotin sulfone as a new tool for synthetic oligosaccharide immobilization: Application to multiple analysis profiling and surface plasmonic analysis of anti-Candida albicans antibody reactivity against alpha and beta (1 -> 2) oligomannosides
Collot M, Sendid B, Fievez A, Savaux C, Standaert-Vitse A, Tabouret M, Drucbert AS, Danze PM, Poulain D, Mallet JM
Journal of Medicinal Chemistry 51, 2008, 6201-6210


Immunogenicity and protective efficacy of DNA vaccines encoding MAP0586c and MAP4308c of Mycobacterium avium subsp paratuberculosis secretome
Roupie V, Leroy B, Rosseels V, Piersoel V, Noel-Georis I, Romano M, Govaerts M, Letesson JJ, Wattiez R, Huygen K
Vaccine 26, 2008, 4783-4794


Nucleotide oligomerization domains 1 and 2: Regulation of expression and function in preadipocytes
Stroh T, Batra A, Glauben R, Fedke I, Erben U, Kroesen A, Heimesaat MM, Bereswill S, Girardin S, Zeitz M, Siegmund B
Journal of Immunology 181, 2008, 3620-3627


Regulation of autoimmune arthritis by self-heat-shock proteins
Moudgil KD, Durai M
Trends in Immunology 29, 2008, 412-418


The dynamics of articular leukocyte trafficking and the immune response to self heat-shock protein 65 influence arthritis susceptibility
Mia MY, Kim EY, Satpute SR, Moudgil KD
Journal of Clinical Immunology 28, 2008, 420-431


Cross-tolerization between Nod1 and Nod2 signaling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages
Kim YG, Park JH , Daignault S, Fukase K, Nunez G
Journal of Immunology 181, 2008, 4340-4346


Roles of galectins in inflammatory bowel disease
Hokama A, Mizoguchi E, Mizoguchi A
World Journal of Gastroenterology 14, 2008, 5133-5137


New serological biomarkers of inflammatory bowel disease
Li XH, Conklin L, Alex P
World Journal of Gastroenterology 14, 2008, 5115-5124


Muramyldipeptide modulates CXCL-8 release of BEAS-2B cells via NOD2
Farkas L, Stoelcker B, Jentsch N, Heitzer S, Pfeifer M, Schulz C
Scandinavian Journal of Immunology 68, 2008, 315-322


Abnormalities in the handling of intracellular bacteria in Crohn's disease: a link between infectious etiology and host genetic susceptibility
Glasser AL, rfeuille-Michaud A
Archivum Immunologiae et Therapiae Experimentalis 56, 2008, 237-244


Severe ileocolitis refractory to standard medical treatment: a diagnostic dilemma
Hofer A, Schmiedel S, Lohse AW, Burchard GD
Internist 49, 2008, 1115-1119


Immunization with a DNA vaccine cocktail induces a Th1 response and protects mice against Mycobacterium avium subsp paratuberculosis challenge
Park SU, Kathaperumal K, McDonough S, Akey B, Huntley J, Bannantine JP, Chang YF
Vaccine 26, 2008, 4329-4337


Antibodies to proteinase 3 prime human oral, lung, and kidney epithelial cells to secrete proinflammatory cytokines upon stimulation with agonists to various toll-like receptors, NOD1, and NOD2
Uehara A, Hirabayashi Y, Takada H
Clinical and Vaccine Immunology 15, 2008, 1060-1066


Mycobacterium avium subspecies paratuberculosis and Crohn's disease granulomas
Toracchio S, El-Zimaity HMT, Urmacher C, Katz S, Graham DY
Scandinavian Journal of Gastroenterology 43, 2008, 1108-1111


Humoral immune responses of type 1 diabetes patients to Mycobacterium avium subsp paratuberculosis lend support to the infectious trigger hypothesis
Sechi LA, Rosu V, Pacifico A, Fadda G, Ahmed N, Zanetti S
Clinical and Vaccine Immunology 15, 2008, 320-326


NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes
Beynon V, Cotofana S, Brand S, Lohse P, Mair A, Wagner S, Mussack T, Ochsenkuhn T, Folwaczny M, Folwaczny C, Glas J, Torok HP
Inflammatory Bowel Diseases 14, 2008, 1033-1040


Beta-PIX and Rac1 GTPase mediate trafficking and negative regulation of NOD2
Eitel J, Krull M, Hocke AC, N'Guessan PD, Zahlten J, Schmeck B, Slevogt H, Hippenstiel S, Suttorp N, Opitz B
Journal of Immunology 181, 2008, 2664-2671


Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: Summary of a symposium
Purohit V, Bode JC, Bode C, Brenner DA, Choudhry MA, Hamilton F, Kang YJ, Keshavarzian A, Rao R, Sartor RB, Swanson C, Turner JR
Alcohol 42, 2008, 349-361


Scenario analysis of changes in consumption of dairy products caused by a hypothetical causal link between Mycobacterium avium subspecies paratuberculosis and Crohn's disease
Groenendaal H, Zagmutt FJ
Journal of Dairy Science 91, 2008, 3245-3258


Risk of infection by biologics
Holle JU, Schinke S, Gross WL
Zeitschrift fur Rheumatologie 67, 2008, 295-304


Pathogenic agents in inflammatory bowel diseases
de Chambrun GP, Colombel JF, Poulain D, rfeuille-Michaud A
Current Opinion in Gastroenterology 24, 2008, 440-447


Toll-like receptor 2 and nucleotide-binding oligomerization domain-2 play divergent roles in the recognition of gut-derived lactobacilli and bifidobacteria in dendritic cells
Zeuthen LH, Fink LN, Frokiaer H
Immunology 124, 2008, 489-502


TLR-activated B cells suppress T cell-mediated autoimmunity
Lampropoulou V, Hoehlig K, Roch T, Neves P, Gomez EC, Sweenie CH, Hao Y, Freitas AA, Steinhoff U, Anderton SM, Fillatreau S
Journal of Immunology 180, 2008, 4763-4773


Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via cryopyrin/NLRP3 independently of Nod2
Marina-Garcia N, Franchi L, Kim YG, Miller D, McDonald C, Boons GJ, Nunez G
Journal of Immunology 180, 2008, 4050-4057


Partial overlap of anti-mycobacterial, and anti-Saccharomyces cerevisiae mannan antibodies in Crohn's disease
Muller S, Schaffer T, Schoepfer AM, Hilty A, Bodmer T, Seibold F
World Journal of Gastroenterology 14, 2008, 3650-3661


Tuberculosis reactivation during immunosuppressive therapy in rheumatic diseases: diagnostic and therapeutic strategies
Keane J, Bresnihan B
Current Opinion in Rheumatology 20, 2008, 443-449


Association of SLC11A1 promoter polymorphisms with the incidence of autoimmune and inflammatory diseases: A meta-analysis
O'Brien BA, Archer NS, Simpson AM, Torpy FR, Nassif NT
Journal of Autoimmunity 31, 2008, 42-51


Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis
Joosten LAB, Heinhuis B, bdollahi-Roodsaz S, Ferwerda G, LeBourhis L, Philpott DJ, Nahori MA, Popa C, Morre SA, van der Meer JWM, Girardin SE, Netea MG, van den Berg WB
Proceedings of the National Academy of Sciences of the United States of America 105, 2008, 9017-9022


Mycobacterial interaction with innate receptors: TLRs, C-type lectins, and NLRs
Jo EK
Current Opinion in Infectious Diseases 21, 2008, 279-286


Sensing intracellular pathogens - NOD-like receptors
Rietdijk ST, Burwell T, Bertin J, Coyle AJ
Current Opinion in Pharmacology 8, 2008, 261-266


Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells
Gerosa F, Baldani-Guerra B, Lyakh LA, Batoni G, Esin S, Winkler-Pickett RT, Consolaro MR, De Marchi M, Giachino D, Robbiano A, Astegiano M, Sambataro A, Kastelein RA, Carra G, Trinchieri G
Journal of Experimental Medicine 205, 2008, 1447-1461


Inhibition of Nod2 signaling and target gene expression by curcumin
Huang S, Zhao L , Kim K, Lee DS, Hwang DH
Molecular Pharmacology 74, 2008, 274-281


Role of the innate immune system in autoimmune inflammatory demyelination
O'Brien K, Fitzgerald DC, Naiken K, Alugupalli KR , Rostami AM, Gran B
Current Medicinal Chemistry 15, 2008, 1105-1115


A NOD2-NALP1 complex mediates caspase-1-dependent IL-1 beta secretion in response to Bacillus anthracis infection and muramyl dipeptide
Hsu LC, Ali SR, McGillivray S, Tseng PH, Mariathasan S, Humke EW, Eckmann L, Powell JJ, Nizet V, Dixit VM, Karin M
Proceedings of the National Academy of Sciences of the United States of America 105, 2008, 7803-7808


Incidence of Mycobacterium avium subspecies paratuberculosis in a population-based cohort of patients with Crohn's disease and control subjects
Bentley RW, Keenan JI, Gearry RB, Kennedy MA, Barclay ML, Roberts RL
American Journal of Gastroenterology 103, 2008, 1168-1172


Correlation between rpoB gene mutation in Mycobacterium avium subspecies paratuberculosis and clinical rifabutin and rifampicin resistance for treatment of Crohn's disease
Beckler DR, Elwasila S, Ghobrial G, Valentine JF, Naser SA
World Journal of Gastroenterology 14, 2008, 2723-2730


In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease
Pulimood AB, Peter S, Rook GWA, Donoghue HD
American Journal of Clinical Pathology 129, 2008, 846-851


Protein-glycan interactions in the control of innate and adaptive immune responses
van Kooyk Y, Rabinovich GA
Nature Immunology 9, 2008, 593-601


The adjuvant effect in infection and autoimmunity
Rose NR
Clinical Reviews in Allergy & Immunology 34, 2008, 279-282


The nexus between atopic disease and autoimmunity: a review of the epidemiological and mechanistic literature
Rabin RL, Levinson AI
Clinical and Experimental Immunology 153 , 2008, 19-30


Monocyte-derived dendritic cells from Crohn patients show differential NOD2/CARD15-dependent immune responses to bacteria
Salucci V, Rimoldi M, Penati C, Sampietro GM, van Duist MM, Matteoli G, Saibeni S, Vecchi M, Ardizzone S, Porro GB, Rescigno M
Inflammatory Bowel Diseases 14, 2008, 812-818


Method for inhibiting angiogenesis for treating angiogenesis associated disorders e.g. osteoarthritis and Crohn's disease, involves administering bis(thiohydrazide amide) derivative to subject
Barsoum J, Foley K
2008, patent


New 5-substituted isoindoline compounds are TNF alpha inhibitors useful to treat, manage or prevent e.g. cancer, Crohn's disease, heart failure, osteoarthritis, stroke, gingivitis, pain, HIV, parasitic disease, hepatitis and asthma
Muller GW, Chen RSC, Ruchelman AL
2008, patent


Gene polymorphisms of the NOD-2/CARD-15 gene and the risk of gastric cancer in Germany
Wex T, Ebert MPA, Kropf S, Dierkes J, Schuttler K, Rocken C, Hocker M, Malfertheiner P
Anticancer Research 28, 2008, 757-762


Bacterial triggers and autoimmune rheumatic diseases
Girschick HJ, Guilherme L, Inman RD, Latsch K, Rihl M, Sherer Y, Shoenfeld Y, Zeidler H, Arienti S, Doria A
Clinical and Experimental Rheumatology 26, 2008, S12-S17


Antibodies against mycobacteria may define a more severe Crohn's disease phenotype and are partly cross-reactive with yeast mannan but are unlikely to be responsible for the induction of anti-Saccharomyces cerevisiae seropositivity
Muller S, Schaffer T, Schoepfer AM, Hilty A, Bodmee T, Seibold F
Swiss Medical Weekly 138 , 2008, 56S


New global map of Crohn's disease: Genetic environmental and socioeconomic correlations
Economou M, Pappas G
Inflammatory Bowel Diseases 14, 2008, 709-720


Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen
Leber JH, Crimmins GT, Raghavan S, Meyer-Morse NP, Cox JS, Portnoy DA
Plos Pathogens 4, 2008, Article Number: 6 Published: JAN 2008


The phosphatidylinositol 3-kinase/Akt pathway negatively regulates Nod2-mediated NF-kappa B pathway
Zhao L, Lee JY, Hwang DH
Biochemical Pharmacology 75, 2008, 1515-1525


The effect of NOD2 activation on TLR2-mediated cytokine responses is dependent on activation dose and NOD2 genotype
Borm MEA, van Bodegraven AA, Mulder CJJ, Kraal G, Bouma G
Genes and Immunity 9, 2008, 274-278


Presentation of lipid antigens to T cells
Mori L, De Libero G
Immunology Letters 117, 2008, 1-8


Genetic resistance of mice to Mycobacterium paratuberculosis is influenced by Slc11a1 at the early but not at the late stage of infection
Roupie V, Rosseels V, Piersoel V, Zinniel DK, Barletta RG, Huygen K
Infection and Immunity 76, 2008, 2099-2105


Intensity of intestinal infection with multiple worm species is related to regulatory cytokine output and immune hyporesponsiveness
Turner JD, Jackson JA, Faulkner H, Behnke J, Else KJ, Kamgno J, Boussinesq M, Bradley JE
Journal of Infectious Diseases 197, 2008, 1204-1212


Regulation of autoimmune arthritis by the pro-inflammatory cytokine interferon-gamma
Kim EY, Chi HH, Bouziane M, Gaur A, Moudgil KD
Clinical Immunology 127, 2008, 98-106


NOD2, the gene responsible for familial granulomatous uveitis, in a mouse model of uveitis
Rosenzweig HL, Martin TM, Jann MM, Planck SR, Davey MP, Kobayashi K, Flavell RA, Rosenbaum JT
Investigative Ophthalmology & Visual Science 49, 2008, 1518-1524


The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals
Hitotsumatsu O, Ahmad RC, Tavares R, Wang M, Philpott D, Turer EE, Lee BL, Shiffin N, Advincula R, Malynn BA, Werts C, Ma A
Immunity 28, 2008, 381-390


Effectiveness of Mycobacterium paratuberculosis isolation from raw milk by means of direct isolation of DNA and classic culture
Szteyn J, Wismiewska-Laszczych A, Rusmynska A
Polish Journal of Veterinary Sciences 11, 2008, 25-28


Immune responses in mice to Mycobacterium avium subsp paratuberculosis following vaccination with a novel 74F recombinant polyprotein
Chen LH, Kathaperumal K, Huang CJ, McDonough SP, Stehman S, Akey B, Huntley J, Bannantine JP, Chang CF, Chang YF
Vaccine 26, 2008, 1253-1262


Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity
Hruz P, Eckmann L
Current Opinion in Gastroenterology 24, 2008, 108-114


Presence and characterization of Mycobacterium avium subspecies para tuberculosis from clinical and suspected cases of Crohn's disease and in the healthy human population in India
Singh AV, Singh SV, Makharia GK, Singh PK, Sohal JS
International Journal of Infectious Diseases 12, 2008, 190-197


High genetic diversity among Mycobacterium avium subsp paratuberculosis strains from German cattle herds shown by combination of IS900 restriction fragment length polymorphism analysis and mycobacterial interspersed repetitive unit-variable-number tandem-repeat typing
Mobius P, Luyven G, Hotzel H, Kohler H
Journal of Clinical Microbiology 46, 2008, 972-981


Characterization of Mycobacterium avium subspecies paratuberculosis disseminated infection in dairy cattle and its association with antemortem test results
Antognoli MC, Garry FB, Hirst HL, Lombard JE, Dennis MM, Gould DH, Salman MD
Veterinary Microbiology 127, 2008, 300-308


Variable responses of formyl peptide receptor haplotypes toward bacterial peptides
Gripentrog JM, Mills JS, Saari GJ, Miettinen HM
Immunogenetics 60, 2008, 83-93


Detection of Mycobacterium avium subspecies paratuberculosis from patients with Crohn's disease using nucleic acid-based techniques: A systematic review and meta-analysis
Abubakar I, Myhill D, Aliyu SH, Hunter PR
Inflammatory Bowel Diseases 14, 2008, 401-410


Crohn's disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross-tolerance to intestinal stimuli
Kullberg BJ, Ferwerda G, de Jong DJ, Drenth JPH, Joosten LAB, van der Meer JWM, Netea MG
Immunology 123, 2008, 600-605


A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion
Till A, Rosenstiel P, Braeutigam K, Sina C, Jacobs G, Oberg HH, Seegert D, Chakraborty T, Schreiber S
Journal of Cell Science 121, 2008, 487-495


Muramyl dipeptide enhances the response to endotoxin to cause multiple organ injury in the anesthetized rat
Murch O, Abdelrahman M, Kapoor A, Thiemermann C
Shock 29, 2008, 388-394


Selective Th2 pattern of cytokine secretion in Mycobacterium avium subsp paratuberculosis infected Crohn's disease
Ren Z, Turton J , Borody T, Pang G, Clancy R
Journal of Gastroenterology and Hepatology 23, 2008, 310-314


Intracellular NOD-like receptors in innate immunity, infection and disease
Franchi L, Park JH, Shaw MH, Marina-Garcia N, Chen G, Kim YG, Nunez G
Cellular Microbiology 10, 2008, 1-8


Macrophage and T cell dynamics during the development and disintegration of mycobacterial Granulomas
Egen JG, Rothfuchs AG, Feng CG, Winter N, Sher A, Germain RN
Immunity 28, 2008, 271-284


Evidence for the involvement of infectious agents in the pathogenesis of Crohns disease
De Hertogh G, Aerssens J, Geboes KP, Geboes K
World Journal of Gastroenterology 14, 2008, 845-852


Muramyl dipeptide-induced differential gene expression in NOD2 mutant and wild-type Crohn's disease patient-derived dendritic cells
Zelinkova Z, van Beelen AJ, de Kort F, Moerland PD, van Themaat EVL, Velde AAT, van Deventer SJ, de Jong EC, Hommes DW
Inflammatory Bowel Diseases 14, 2008, 186-194


Is alpha-dystroglycan the missing link in the mechanism of enterocyte uptake and translocation of Mycobacterium avium para tuberculosis?
Warth A
Medical Hypotheses 70, 2008, 369-374


Acquired autoimmunity after viral vaccination is caused by molecular mimicry and antigen complimentarity in the presence of an immunologic adjuvant and specific HLA patterns
Waisbren BA
Medical Hypotheses 70, 2008, 346-348


Novel CARD15/NOD2 mutations in Finnish patients with Crohn's disease and their relation to phenotypic variation in vitro and in vivo
Loppalainen M, Paavola-Sakki P, Halme L, Turunen U, Farkkila M, Repo H, Kontula K
Inflammatory Bowel Diseases 14, 2008, 176-185


Abnormal O-glycosylation of CD43 may account for some features of Wiskott-Aldrich syndrome
Khan S, Holding S, Dore PC, Sewell WAC
Medical Hypotheses 70, 2008, 269-272


Lipopentapeptide induces a strong host humoral response and distinguishes Mycobacterium avium subsp paratuberculosis from M-avium subsp avium
Biet F, Bay S, Thibault VC, Euphrasie D, Grayon M, Ganneau C, Lanotte P, Daffe M, Gokhale R, Etienne G, Reyrat JM
Vaccine 26, 2008, 257-268


Engagement of NOD2 has a dual effect on proIL-1 beta mRNA transcription and secretion of bioactive IL-1 beta
Ferwerda G, Krarner M, de Jong D, Piccini A, Joosten LA, DevesaGiner I, Girardin SE, Adema GJ, van der Meer JWM, Kullberg BJ, Rubartelli A, Netea MG
European Journal of Immunology 38, 2008, 184-191


Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis
Watanabe T, Asano N, Murray PJ, Ozato K, Tailor P, Fuss IJ, Kitani A, Strober W
Journal of Clinical Investigation 118, 2008, 545-559


Innate immunity in inflammatory bowel disease: a disease hypothesis
Marks DJB, Segal AW
Journal of Pathology 214, 2008, 260-266


Mycobacterium marinum infection complicating Crohn's disease, treated with infliximab
Fallon JC, Patchett S, Gulmann C, Murphy GM
Clinical and Experimental Dermatology 33, 2008, 43-45


Mycobacterium avium subspecies paratuberculosis bacteremia in type 1 diabetes mellitus: An infectious trigger?
Sechi LA, Paccagnini D, Salza S, Pacifico A, Ahmed N, Zanetti S
Clinical Infectious Diseases 46, 2008, 148-149


The evidence for Mycobacterium paratuberculosis in Crohn's disease
Behr MA, Kapur V
Current Opinion in Gastroenterology 24, 2008, 17-21


TAK1 is a central mediator of NOD2 signaling in epidermal cells
Kim JY, Omori E , Matsumoto K, Nunez G, Ninomiya-Tsuji J
Journal of Biological Chemistry 283, 2008, 137-144


NLR proteins: integral members of innate immunity and mediators of inflammatory diseases
Wilmanski JM, Petnicki-Ocwieja T, Kobayashi KS
Journal of Leukocyte Biology 83, 2008, 13-30


Sympathetic nervous modulation of the skin innate and adaptive immune response to peptidoglycan but not lipopolysaccharide: Involvement of beta-adrenoceptors and relevance in inflammatory diseases
Manni M, Maestroni GJM
Brain Behavior and Immunity 22, 2008, 80-88


Comparison of 13 single-round and nested PCR assays targeting IS900, ISMav2, f57 and locus 255 for detection of Mycobacterium avium subsp paratuberculosis
Mobius P, Hotzel H, Rassbach A, Kohler H
Veterinary Microbiology 126, 2008, 324-333


Diagnostic system for detection of Mycobacterium avium subsp paratuberculosis
Stephan R
Journal fur Verbraucherschutz und Lebensmittelsicherheit-Journal of Consumer Protection and Food Safety 2, 2007, 222-227


Functional characterization of two novel 5 ' untranslated exons reveals a complex regulation of NOD2 protein expression
Rosenstiel P, Huse K, Franke A, Hampe J, Reichwald K, Platzer C, Roberts RG, Mathew CG, Platzer M, Schreiber S
Bmc Genomics 8, 2007, Article Number: 472 Published: DEC 20 2007


Nod-like receptors: Cytosolic watchdogs for immunity against pathogens
Sirard JC, Vignal C, Dessein R, Chamaillard M
Plos Pathogens 3, 2007, 1829-1836


Scenario and economic analysis of a hypothetical link between MAP and Crohn's disease
Groenendaal H, Zagmutt FZ
Journal of Dairy Science 90, 2007, 671-672


Splicing of NOD2 (CARD 15) RNA transcripts
Leung E, Hong JW, Fraser A, Krissansen GW
Molecular Immunology 44, 2007, 284-294


The role of microbes in Crohn's disease
Eckburg PB, Relman DA
Clinical Infectious Diseases 44, 2007, 256-262


Multispecific myeloid defensins
Lehrer RI
Current Opinion in Hematology 14, 2007, 16-21


Chronic inflammation: importance of NOD2 and NALP3 in interleukin-1 beta generation
Ferrero-Miliani L, Nielsen OH, Andersen PS, Girardin SE
Clinical and Experimental Immunology 147, 2007, 227-235


Polymorphisms in genes related to bacterial lipopolysaccharide/peptidoglycan signaling and gastric precancerous lesions in a population at high risk for gastric cancer
Kato I, Canzian F, Plummer M, Franceschi S, van Doorn LJ, Vivas J, Lopez G, Lu YH, Gioia-Patricola L, Severson RK, Schwartz AG, Munoz N
Digestive Diseases and Sciences 52, 2007, 254-261


Innate recognition of intracellular bacteria
Delbridge LM, O'Riordan MXD
Current Opinion in Immunology 19, 2007, 10-16


One-step, nanoparticle-mediated bacterial detection with magnetic relaxation
Kaittanis C, Naser SA, Perez JM
Nano Letters 7, 2007, 380-383


Inflammatory bowel disease genetics: Nod2
Cho JH, Abraham C
Annual Review of Medicine 58, 2007, 401-416


Genetics of the innate immune response in inflammatory bowel disease
Van Limbergen J, Russell RK, Nimmo ER, Ho GT, Arnott ID, Wilson DC, Satsangi J
Inflammatory Bowel Diseases 13, 2007, 338-355


Field testing of an enhanced direct-fecal polymerase chain reaction procedure, bacterial culture of feces, and a serum enzyme-linked immunosorbent assay for detecting Mycobacterium avium subsp paratuberculosis infection in adult dairy cattle
Scott HM, Fosgate GT, Libal MC, Sneed LW, Erol E, Angulo AB, Jordan ER
American Journal of Veterinary Research 68, 2007, 236-245


Johne's disease
Hayton AJ
Cattle Practice 15, 2007, 79-87


Survey of ground beef for the detection of Mycobacterium avium paratuberculosis
Jaravata CV, Smith WL, Rensen GJ, Ruzante J, Cullor JS
Foodborne Pathogens and Disease 4, 2007, 103-106


Efficacy of spheroplastic and cell-wall competent vaccines for Mycobacterium avium subsp paratuberculosis in experimentally-challenged baby goats
Hines ME, Stiver S, Giri D, Whittington L, Watson C, Johnson J, Musgrove J, Pence M, Hurley D, Baldwin C, Gardner IA, Aly S
Veterinary Microbiology 120, 2007, 261-283


A case-control study of drinking water and dairy products in Crohn's disease- Further investigation of the possible role of mycobacterium avium paratuberculosis
Abubakar I, Myhill DJ, Hart AR, Lake IR, Harvey I, Rhodes JM, Robinson R, Lobo AJ, Probert CSJ, Hunter PR
American Journal of Epidemiology 165, 2007, 776-783


Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo
Cartwright N, Murch O, McMaster SK, Paul-Clark MJ, van Heel DA, Ryffel B, Quesniaux VFJ, Evans TW, Thiemermann C, Mitchell JA
American Journal of Respiratory and Critical Care Medicine 175, 2007, 595-603


Development of a new, combined rapid method using phage and PCR for detection and identification of viable Mycobacterium paratuberculosis bacteria within 48 hours
Stanley EC, Mole RJ, Smith RJ, Glenn SM, Barer MR, McGowan M, Rees CED
Applied and Environmental Microbiology 73, 2007, 1851-1857


Persistence of Mycobacterium avium subspecies paratuberculosis in rabbits: the interplay between horizontal and vertical transmission
Judge J, Davidson RS, Marion G, White PCL, Hutchings MR
Journal of Applied Ecology 44, 2007, 302-311


Testing the interaction between NOD-2 status and serological response to Mycobacterium paratuberculosis in cases of inflammatory bowel disease
Bernstein CN, Wang MH, Sargent M, Brant SR, Collins MT
Journal of Clinical Microbiology 45, 2007, 968-971


Pulsed-field gel electrophoresis profile homogeneity of Mycobacterium avium subsp paratuberculosis isolates from cattle and heterogeneity of those from sheep and goats
Sevilla I, Garrido JM, Geijo M, Juste RA
Bmc Microbiology 7, 2007, Article Number: 18 Published: MAR 12 2007


Nod1 mediates cytoplasmic sensing of combinations of extracellular bacteria
Ratner AJ, Aguilar JL, Shchepetov M, Lysenko ES, Weiser JN
Cellular Microbiology 9, 2007, 1343-1351


Adherent-invasive Escherichia coli isolated from Crohn's disease patients induce granulomas in vitro
Meconi S, Vercellone A, Levillain F, Payre B, Al Saati T, Capilla F, Desreumaux P, rfeuille-Michaud A, Altare F
Cellular Microbiology 9, 2007, 1252-1261


A lectin array-based methodology for the analysis of protein glycosylation
Rosenfeld R, Bangio H, Gerwig GJ, Rosenberg R, Aloni R, Cohen Y, Amor Y, Plaschkes I, Kamerling JP, Maya RBY
Journal of Biochemical and Biophysical Methods 70, 2007, 415-426


Antigen discovery: A postgenomic approach to paratuberculosis diagnosis
Leroy B, Roupie V, Noel-Georis I, Rosseels V, Walravens K, Govaerts M, Huygen K, Wattiez R
Proteomics 7, 2007, 1164-1176


Relationship between Mycobacterium avium subspecies paratuberculosis, IL-1 alpha, and TRAF1 in primary bovine monocyte-derived macrophages
Chiang SK, Sommer S, Aho AD, Kiupel M, Colvin C, Tooker B, Coussens PM
Veterinary Immunology and Immunopathology 116, 2007, 131-144


Peripheral blood mononuclear cell proliferative responses to soluble and particulate heat shock protein 65 in health and inflammatory bowel disease
Pele LC, Thompson SJ, Kirkham B, Thompson RPH, Powell JJ
Inflammation Research 56, 2007, 143-148


Functional consequences of NOD2/CARD15 mutations in Crohn disease
Quaglietta L, te Velde T, Staiano A, Troncone R, Hommes DW
Journal of Pediatric Gastroenterology and Nutrition 44, 2007, 529-539


Antigenic complementarity in the induction of autoimmunity: A general theory and review
Root-Bernstein R
Autoimmunity Reviews 6, 2007, 272-277


Improved template DNA preparation procedure for detection of Mycobacterium avium subsp paratuberculosis in milk by PCR
Gao A, Mutharia L, Raymond M, Odumeru J
Journal of Microbiological Methods 69, 2007, 417-420


Mycobacterial Hsp65-IgG-expressing tolerogenic B cells confer protection against adjuvant-induced arthritis in Lewis rats
Satpute SR, Soukhareva N, Scott DW, Moudgil KD
Arthritis and Rheumatism 56, 2007, 1490-1496


CARD15 variants determine a disturbed early response of monocytes to adherent-invasive Escherichia coli strain LF82 in Crohn's disease
Peeters H, Bogaert S, Laukens D, Rottiers P, De Keyser F, rfeuille-Michaud A, Glasser AL, Elewaut D, De Vos M
International Journal of Immunogenetics 34, 2007, 181-191


The NOD2-RICK complex signals from the plasma membrane
Lecine P, Esmiol S, Metais JY, Nicoletti C, Nourry C, McDonald C, Nunez G, Hugot JP, Borg JP , Ollendorff V
Journal of Biological Chemistry 282, 2007, 15197-15207


Mycobacteria and Crohn's disease: The endless story
Prantera C
Digestive and Liver Disease 39, 2007, 452-454


Molecular evidence for Mycobacterium avium subspecies paratuberculosis (MAP) in Crohn's disease correlates with enhanced TNF-alpha secretion
Clancy R, Ren Z , Turton J, Pang G, Wettstein A
Digestive and Liver Disease 39, 2007, 445-451


Anti-mycobacterial therapy in Crohn's disease heals mucosa with longitudinal scars
Borody TJ, Bilkey S, Wettstein AR, Leis S, Pang G, Tye S
Digestive and Liver Disease 39, 2007, 438-444


Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide
Windheim M, Lang C, Peggie M, Plater LA, Cohen P
Biochemical Journal 404, 2007, 179-190


How NOD2 mutations predispose to Crohn's disease?
Vignal C, Singer E, Peyrin-Biroulet L, Desreumaux P, Chamaillard M
Microbes and Infection 9, 2007, 658-663


NOD-like receptors and human diseases
Rosenstiel P, Till A, Schreiber S
Microbes and Infection 9, 2007, 648-657


Role of Nods in bacterial infection
Le Bourhis L, Werts C
Microbes and Infection 9, 2007, 629-636


Contribution of the NOD1/CARD4 insertion/deletion polymorphism +32656 to inflammatory bowel disease in northern Europe
Van Limbergen J, Russell RK, Nimmo ER, Torkvist L , Lees CW, Drummond HE, Smith L, Anderson NH, Gillett PM, McGrogan P, Hassan K, Weaver LT, Bisset WM, Mahdi G, Arnott ID, Sjoqvist U, Lordal M, Farrington SM, Dunlop MG, Wilson DC, Satsangi J
Inflammatory Bowel Diseases 13, 2007, 882-889


Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion
Rosenstiel P, Sina C, End C, Renner M, Lyer S, Till A, Hellmig S, Nikolaus S, Folsch UR, Helmke B, Autschbach F, Schirmacher P, Kioschis P, Hafner M, Poustka A, Mollenhauer J, Schreiber S
Journal of Immunology 178, 2007, 8203-8211


Control of T cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis
Grigorian A, Lee SU, Tian WQ, Chen IJ, Gao GY, Mendelsohn R, Dennis JW, Demetriou M
Journal of Biological Chemistry 282, 2007, 20027-20035


Genome and transcriptome scale portrait of sigma factors in Mycobacterium avium subsp paratuberculosis
Sechi LA, Felis GE, Ahmed N, Paccagnini D, Usai D, Ortu S, MoliCotti P, Zanetti S
Infection Genetics and Evolution 7, 2007, 424-432


MDP-induced interleukin-1 beta processing requires Nod2 and CIAS1/NALP3
Pan QL, Mathison J, Fearns C, Kravchenko VV, Correia JD, Hoffman HM, Kobayashi KS, Bertin J, Grant EP, Coyle AJ, Sutterwala FS , Ogura Y, Flavell RA, Ulevitch RJ
Journal of Leukocyte Biology 82, 2007, 177-183


Effective heat inactivation of Mycobacterium avium subsp paratuberculosis in raw milk contaminated with naturally infected feces
Rademaker JLW, Vissers MMM, Giffel MCT
Applied and Environmental Microbiology 73, 2007, 4185-4190


Galectins: matricellular glycan-binding proteins linking cell adhesion, migration, and survival
Elola MT, Wolfenstein-Todel C, Troncoso MF, Vasta GR, Rabinovich GA
Cellular and Molecular Life Sciences 64, 2007, 1679-1700


Prevalence of Mycobacterium avium subspecies paratuberculosis in swiss raw milk cheeses collected at the retail level
Stephan R, Schumacher S, Tasara T, Grant IR
Journal of Dairy Science 90, 2007, 3590-3595


Identification of a QTL on BTA20 affecting susceptibility to Mycobacterium avium ssp paratuberculosis infection in US Holsteins
Gonda MG, Kirkpatrick BW, Shook GE, Collins MT
Animal Genetics 38, 2007, 389-396


Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis
Green RS, Stone EL, Tenno M, Lehtonen E, Farquhar MG, Marth JD
Immunity 27, 2007, 308-320


Influence of Mycobacterium avium subsp paratuberculosis on colitis development and specific immune responses during disease
Singh UP, Singh S, Singh R, Karls RK, Quinn FD, Potter ME, Lillard JW
Infection and Immunity 75, 2007, 3722-3728


New variable-number tandem-repeat markers for typing Mycobacterium avium subsp paratuberculosis and M-avium strains: Comparison with IS900 and IS1245 restriction fragment length polymorphism typing
Thibault VC, Grayon M, Boschiroli ML, Hubbans C, Overduin P, Stevenson K, Gutierrez MC, Supply P, Biet F
Journal of Clinical Microbiology 45, 2007, 2404-2410


Autoreactive antibodies are present in sheep with Johne's disease and cross-react with Mycobacterium avium subsp paratuberculosis antigens
Berger S, Bannantine JP, Griffin JFT
Microbes and Infection 9, 2007, 963-970


Innate immune response triggers lupus-like autoimmune disease
Paulson JC
Cell 130, 2007, 589-591


NOD2 and defensins: translating innate to adaptive immunity in Crohn's disease
Peyrin-Biroulet L, Chamaillard M
Journal of Endotoxin Research 13, 2007, 135-139


The Paneth cell alpha-defensin deficiency of ileal Crohn's disease is linked to Wnt/Tcf-4
Wehkamp J, Wang G, Kubler I, Nuding S, Gregorieff A, Schnabel A, Kays RJ, Fellermann K, Burk O, Schwab M, Clevers H, Bevins CL, Stange EF
Journal of Immunology 179, 2007, 3109-3118


Mycobacterium avium subspecies paratuberculosis and Crohn's disease: a systematic review and meta-analysis
Feller M, Huwiler K, Stephan R, Altpeter E, Shang A, Furrer H, Pfyffer GE, Jemmi T, Baumgartner A, Egger M
Lancet Infectious Diseases 7, 2007, 607-613


Coordinated regulation of toll-like receptor and NOD2 signaling by k63-linked polyubiquitin chains
Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA, Cantley LC
Molecular and Cellular Biology 27, 2007, 6012-6025


Effect of high pressure and pasteurization on Mycobacterium avium ssp paratuberculosis in milk
Donaghy JA, Linton M, Patterson MF, Rowe MT
Letters in Applied Microbiology 45, 2007, 154-159


Cell wall beta-glucan derived from Candida albicans acts as a trigger for autoimmune arthritis in SKG mice
Hida S, Miura NN, Adachi Y, Ohno N
Biological & Pharmaceutical Bulletin 30, 2007, 1589-1592


Non-chemical method of DNA recovery and characterization of Mycobacterium avium subspecies paratuberculosis using IS900PCR
Singh SV, Singh PK, Singh AV, Sohal JS, Subodh S, Narayanasamy K
Indian Journal of Experimental Biology 45, 2007, 812-816


An emerging role for galectins in tuning the immune response: Lessons from experimental models of inflammatory disease, autoimmunity and cancer
Rabinovich GA, Liu FT, Hirashima M, Anderson A
Scandinavian Journal of Immunology 66, 2007, 143-158


MAP-associated Crohn's disease MAP, Koch's postulates, causality and Crohn's disease
Chamberlin W, Borody T, Naser S
Digestive and Liver Disease 39, 2007, 792-794


New serological markers in inflammatory bowel disease are associated with complicated disease behaviour
Ferrante M, Henckaerts L, Joossens M, Pierik M, Joossens S, Dotan N, Norman GL, Altstock RT, Van Steen K, Rutgeerts P, Van Assche G, Vermeire S
Gut 56, 2007, 1394-1403


Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum
Baumgart M, Dogan B, Rishniw M, Weitzman G, Bosworth B, Yantiss R, Orsi RH, Wiedmann M, McDonough P, Kim SG, Berg D, Schukken Y, Scherl E, Simpson KW
Isme Journal 1, 2007, 403-418


Mycobacterium paratuberculosis is recognized by Toll-like receptors and NOD2
Ferwerda G, Kullberg BJ, de Jong DJ, Girardin SE , Langenberg DML, van Crevel R, Ottenhoff THM, van der Meer JWM, Netea MG
Journal of Leukocyte Biology 82, 2007, 1011-1018


The Nodosome: Nod1 and Nod2 control bacterial infections and inflammation
Tattoli I, Travassos LH, Carneiro LA, Magalhaes JG, Girardin SE
Seminars in Immunopathology 29, 2007, 289-301


Early atherosclerosis and autoantibodies to heat-shock proteins and oxidized LDL in systemic sclerosis
Sherer Y, Cerinic MM, Bartoli F, Blagojevic J, Conforti ML, Gilburd B, Ehrenfeld M, Shoenfeld Y
Autoimmunity, Pt D 1108, 2007, 259-267


Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy
Van Limbergen J, Nimmo ER, Russell RK, Drummond HE, Smith L, Anderson NH, Davies G, Arnott ID, Wilson DC, Satsangi J
Human Molecular Genetics 16, 2007, 2175-2186


Mycobacterium avium subspecies paratuberculosis diagnosis and strain typing - Present status and future developments
Sohal JS, Singh SV, Subhodh S, Singh AV, Singh PK, Sheoran N, Sandhu K, Narayansamy K, Maitra A
Indian Journal of Experimental Biology 45, 2007, 843-852


Polymorphisms in gyrA and gyrB subsp paratuberculosis genes among mycobacterium avium type I, II, and III isolates
Castellanos E, Aranaz A, Romero B, De Juan L, Alvarez J, Bezos J, Rodriguez S, Stevenson K, Mateos A, Dominguez L
Journal of Clinical Microbiology 45, 2007, 3439-3442


Comparative evaluation of positive tests to Mycobacterium avium subsp paratuberculosis in clinically healthy sheep and goats in South-West Greece using molecular techniques, serology, and culture
Ikonomopoulos J, Balaskas C, Kantzoura B, Fragiadaki E, Pavlik I, Bartos M, Lukas JC, Gazouli M
Veterinary Journal 174, 2007, 337-343


Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: The role of TLR2 and NOD2
Wu L, Feng BS, He SH, Zheng PY, Croitoru K, Yang PC
Immunology and Cell Biology 85, 2007, 538-545


Innate immunity in inflammatory bowel disease
Yamamoto-Furusho JK, Podolsky DK
World Journal of Gastroenterology 13, 2007, 5577-5580


Intracellular NOD-like receptors in host Defense and disease
Kanneganti TD, Lamkanfi M, Nunez G
Immunity 27, 2007, 549-559


The pathogen recognition sensor, NOD2, is variably expressed in patients with pulmonary tuberculosis
Lala S, Dheda K , Chang JS, Huggett JF, Kim LU, Johnson MA, Rook GAW, Keshav S, Zumla A
Bmc Infectious Diseases 7, 2007, Article Number: 96 Published: AUG 16 2007


Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobactefium tuberculosis
Gandotra S, Jang S, Murray PJ, Salgame P, Ehrt S
Infection and Immunity 75, 2007, 5127-5134


Defining the stressome of Mycobacterium avium subsp paratuberculosis in vitro and in naturally infected cows
Wu CW, Schmoller SK, Shin SJ, Talaat AM
Journal of Bacteriology 189, 2007, 7877-7886


Primer: signal transduction in rheumatic disease - a clinician's guide
Sweeney SE, Firestein GS
Nature Clinical Practice Rheumatology 3, 2007, 651-660


Identification of atherosclerosis-associated conformational heat shock protein 60 epitopes by phage display and structural alignment
Perschinka H, Wellenzohn B, Parson W, van der Zee R, Willeit J, Kiechl S, Wick G
Atherosclerosis 194, 2007, 79-87


Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?
Marik C, Felts PA, Bauer J, Lassmann H, Smith KJ
Brain 130, 2007, 2800-2815


The hygiene hypothesis and the increamng prevalence of chronic inflammatory disorders
Rook GAW
Transactions of the Royal Society of Tropical Medicine and Hygiene 101, 2007, 1072-1074


Epidemiological evidence for Mycobacterium avium subspecies paratuberculosis as a cause of Crohn's disease
Uzoigwe JC, Khaitsa ML, Gibbs PS
Epidemiology and Infection 135, 2007, 1057-1068


NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction
Yang ZQ, Fuss IJ, Watanabe T, Asano N, Davey MP, Rosenbaum JT, Strober W, Kitani A
Gastroenterology 133, 2007, 1510-1521


Microbial mannan inhibits bacterial killing by macrophages: A possible pathogenic mechanism for Crohn's disease
Mpofu CM, Campbell BJ, Subramanian S, Marshall-Clarke S, Hart CA, Cross A, Roberts CL, Mcgoldrick A, Edwards SW, Rhodes JM
Gastroenterology 133, 2007, 1487-1498


T cells against the pathogenic and protective epitopes of heat-shock protein 65 are crossreactive and display functional, similarity: Novel aspect of regulation of autoimmune arthritis
Durai M, Kim HR , Bala K, Moudgil KD
Journal of Rheumatology 34, 2007, 2134-2143


Myobacterium avium subspecies paratubercolusis infects and multiple in enteric glial cells
Sechi LA, Ruehl A, Ahmed N, Usai D, Paccagnini D, Felis GE, Zanetti S
World Journal of Gastroenterology 13, 2007, 5731-5735


The etiology of Mycobacterium avium subspecies paratuberculosis in Crohn's disease
Alluwaimi AM
Saudi Medical Journal 28 , 2007, 1479-1484


Dietary microparticles and their impact on tolerance and immune responsiveness of the gastrointestinal tract
Powell JJ, Thoree V, Pele LC
British Journal of Nutrition 98, 2007, S59-S63


Stress, heat shock proteins, and autoimmunity: How immune responses to heat shock proteins are to be used for the control of chronic inflammatory diseases
Van Eden W, Wick G, Albani S, Cohen I
Stress Responses in Biology and Medicine 1113, 2007, 217-237


Mass spectrometric analysis of intact lipooligosaccharide: Direct evidence for O-acetylated sialic acids and discovery of O-linked glycine expressed by Campylobacter jejuni
Dzieciatkowska M, Brochu D, van Belkum A, Heikema AP, Yuki N, Houliston RS, Richards JC, Gilbert M, Li JJ
Biochemistry 46, 2007, 14704-14714


Chronic stimulation of Nod2 mediates tolerance to bacterial products
Hedl M, Li J, Cho JH, Abraham C
Proceedings of the National Academy of Sciences of the United States of America 104, 2007, 19440-19445


Nod-like receptors in innate immunity and inflammatory diseases
Carneiro LAM, Travassos LH, Girardin SE
Annals of Medicine 39, 2007, 581-593


Mycobacterium avium subspecies paratuberculosis infection in cases of irritable bowel syndrome and comparison with Crohn's disease and Johne's disease: Common neural and immune pathogenicities
Scanu AM, Bull TJ, Cannas S, Sanderson JD, Sechi LA, Dettori G, Zanetti S, Hermon-Taylor J
Journal of Clinical Microbiology 45, 2007, 3883-3890


Nod1 and Nod2 in innate immunity and human inflammatory disorders
Le Bourhis L, Benko S, Girardin SE
Biochemical Society Transactions 35, 2007, 1479-1484


Results of a bulk milk quality assurance programme for paratuberculosis
Weber MF, van Schaik G, van Weering HJ
Cattle Practice 15, 2007, 261-+


A survey to estimate the herd level prevalence of paratuberculosis in the dairy herd of the United Kingdom
Caldow G, Strain SAJ, Chapman Z, Kemp R, Cook AJ
Cattle Practice 15, 2007, 169-171


Heterozygous nucleotide-binding oligomerization domain-2 mutations affect monocyte maturation in Crohn's disease
Granzotto M, Fabbro E, Maschio M, Martelossi S , Quaglia S, Tommasini A, Presani G, Ventura A
World Journal of Gastroenterology 13, 2007, 6191-6196


Scenario and economic analysis of a hypothetical link between MAP and Crohn's disease
Groenendaal H, Zagmutt FZ
Journal of Animal Science 85, 2007, 671-672


The role of microbial agents in the pathogenesis of inflammatory bowel disease
Huda-Faujan N, Mustafa S, Manaf MYA, Yee LY, bu Bakar F
Reviews in Medical Microbiology 18, 2007, 47-53


Visualization of Mycobacterium avium in Crohn's tissue by oil-immersion microscopy
Jeyanathan M, Boutros-Tadros O, Radhi J, Semret M , Bitton A, Behr MA
Microbes and Infection 9, 2007, 1567-1573


Scenario and economic analysis of a hypothetical link between MAP and Crohn's disease
Grocnendaal H, Zagmutt FZ
Poultry Science 86, 2007, 671-672


NOD1 gene E266K polymorphism is associated with disease susceptibility but not with disease phenotype or NOD2/CARD15 in Hungarian patients with Crohn's disease
Molnar T, Hofner P, Nagy F, Lakatos PL, Fischer S, Lakatos L, Kovacs A, Altorjay I, Papp M, Palatka K, Demeter P, Tulassay Z, Nyari T, Miheller P, Papp J, Mandi Y, Lonovics J
Digestive and Liver Disease 39, 2007, 1064-1070


Carboxyl terminus of the 34 kDa protein of Mycobacterium paratuberculosis shares homologous B-cell epitopes with Mycobacterium avium and Mycobacterium intracellulare
Malamo M, Okazaki K, Sakoda Y, Kida H
Veterinary Record 161, 2007, 853-857


Evaluation of in situ methods used to detect Mycobacterium avium subsp paratuberculosis in samples from patients with Crohn's disease
Jeyanathan M, Alexander DC, Turenne CY, Girard C, Behr MA
Journal of Clinical Microbiology 44, 2006, 2942-2950


Mycobacterium avium sub. paratuberculosis in tissue samples of Crohn's disease patients
Sechi LA, Mura M, Tanda E, Lissia A, Fadda G, Zanetti S
New Microbiol. 27, 2004, 75-77